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Digital holographic microscopy for non-invasive monitoring of cell cycle arrest in l929 cells.

Digital holographic microscopy (DHM) has emerged as a powerful non-invasive tool for cell analysis. It has the capacity to analyse multiple parameters simultaneously, such as cell- number, confluence and phase volume. This is done while cells are still adhered and growing in their culture flask. The aim of this study was to investigate whether DHM was able to monitor drug-induced cell cycle arrest

Plaque-associated lipids in Alzheimer's diseased brain tissue visualized by nonlinear microscopy.

By simultaneous coherent anti-Stokes Raman scattering (CARS) and 2-photon fluorescence microscopy of Thioflavin-S stained Alzheimer´s diseased human brain tissues, we show evidence of lipid deposits co-localizing with fibrillar β-amyloid (Aβ) plaques. Two lipid morphologies can be observed; lamellar structures and coalescing macro-aggregates of sub-micron sizes to ~25 μm. No significant lipid depo

Yeast "make-accumulate-consume" life strategy evolved as a multi-step process that predates the whole genome duplication.

When fruits ripen, microbial communities start a fierce competition for the freely available fruit sugars. Three yeast lineages, including baker's yeast Saccharomyces cerevisiae, have independently developed the metabolic activity to convert simple sugars into ethanol even under fully aerobic conditions. This fermentation capacity, named Crabtree effect, reduces the cell-biomass production but pro

Functional text geometry: The essentials of Perspective Text Analysis

The production of string rotation and pattern dynamics through the generation of text must build on the presence of a reversible rotary motor which has a synthesizing capacity. This is the discovered AaO-mechanism, which has the power to capture synthesis through emerging AaO-rings. Further, the transcription through the Functional Clause (FC) provides the foundation for their differentiation and

Replication of genomewide associations with allergic sensitization And allergic rhinitis

Background: Three genomewide metastudies have recently reported associations with self-reported allergic rhinitis and allergic sensitization. The three studies together identified a set of 37 loci but showed low concordance. This study investigates the reproducibility of the detected single nucleotide polymorphism (SNP) associations in an extensively characterized longitudinal cohort, BAMSE. Metho

"I wouldn't call them Muslims!": Constructing a Respectable Islam

This article addresses the understanding of Islam of nine young adult Muslims living in the Malmo and Copenhagen region. 1 Throughout the interviews with the young adults, they mark their distance from what they perceive as unacceptable forms of Islamic ideas and practices, labeling these ideas as extremist and inconsistent. They develop discursive techniques of distancing themselves from the medi

Selective reduction of nitroaromatic compounds on silver nanoparticles by visible light

For the first time, we report experimentally and theoretically that nitroaromatic compounds, 2,4-dinitrobenzenethiol and 4-chloro-2-nitrobenzenethiol, on silver sols can be selectively reduced to 2-amino-4-nitrobenzenethiol and 2-amino-4-chlorobenzenethiol simply by irradiating with a visible light in ambient conditions, and the selective photoreduction is a very facile process. The results of qua

Body Mass Index Is Associated with Impaired Semen Characteristics and Reduced Levels of Anti-Müllerian Hormone across a Wide Weight Range.

There is still controversy as to how body mass index (BMI) affects male reproduction. We investigated how BMI is associated with semen quality and reproductive hormones in 166 men, including 38 severely obese men. Standard semen analysis and sperm DNA integrity analysis were performed, and blood samples were analysed for reproductive hormones. Adjusted for age and time of abstinence, BMI was negat

Berättelser om adoption

Popular Abstract in SwedishI avhandlingen undersöks adoptionsberättelser i en svensk kontext. Syftet är tvåfaldigt: För det första, hur adoption beskrivs av vuxna adopterade, för det andra, hur adoption konstrueras i dagspress. Adopterades sätt att skapa mening kring att ”vara adopterad” är i fokus, så är även dessa personliga berättelsers samspel med kulturellt gångbara diskurser på adoptionsområThis dissertation explores adoption stories in a Swedish context. The aim is two-fold: First, how adoption is presented by adopted adults; second, how adoption is constructed in the press. The way adoptees create meaning of “being adopted” is investigated; the way those stories are shaped culturally is also explored. The study was conducted in a qualitative tradition with a constructionist and nar

Clonal Evolution through Loss of Chromosomes and Subsequent Polyploidization in Chondrosarcoma.

Near-haploid chromosome numbers have been found in less than 1% of cytogenetically reported tumors, but seem to be more common in certain neoplasms including the malignant cartilage-producing tumor chondrosarcoma. By a literature survey of published karyotypes from chondrosarcomas we could confirm that loss of chromosomes resulting in hyperhaploid-hypodiploid cells is common and that these cells m

A dominant suppressive MHC class II haplotype interacting with autosomal genes controls autoantibody production and chronicity of arthritis

Objective To investigate the genetic control of chronic arthritis and collagen epitope specific antibody responses in an experimental model for rheumatoid arthritis. Methods The chronic collagen induced arthritis (CCIA) model was used, induced with collagen type II (CII) in mineral oil lacking mycobacterium in BALB/c (n=24), B10.Q (n=44), (BALB/c x B10.Q) F1 (n=85) and B10.Q x (BALB/c x B10.Q) N2

Search for second generation scalar leptoquarks in pp collisions at root s=7 TeV with the ATLAS detector

The results of a search for the production of second generation scalar leptoquarks are presented for final states consisting of either two muons and at least two jets or a muon plus missing transverse momentum and at least two jets. A total of 1.03 fb(-1) integrated luminosity of proton-proton collision data produced by the Large Hadron Collider at root s = 7 TeV and recorded by the ATLAS detector

Reflection and transmission properties of a wall-floor building element: comparison between finite element model and experimental data.

Changes in the Swedish construction code introduced in 1994 enabled the construction of wooden multi-storey buildings. The main issue in those is disturbing vibrations and noise propagating throughout the construction. Therefore, gaining knowledge about their behavior is of crucial importance for the industry. In this study, a mockup of a wall/floor junction was investigated by comparing both expe