Filetype
Chronic exposure of pancreatic islets to elevated levels of palmitate leads to beta-cell dysfunction. We examined possible involvement of mitogenactivated protein kinases (MAPKs) and caspase-3 in palmitate-induced beta-cell dysfunction and tested the influence of the anti-diabetic drug rosiglitazone (ROZ). Palmitate amplified glucose-stimulated augmentation of intracellular free calcium ([Ca(2+)](
By means of scanning tunneling microscopy/spectroscopy (STM/STS), photoelectron spectroscopy, and first-principles calculations, we have studied the bismuth (Bi) adsorbate-stabilized InSb(100) substrate surface which shows a c(2X6) low-energy electron diffraction pattern [thus labeled Bi/InSb(100)c(2X6) surface] and which includes areas with metallic STS curves as well as areas with semiconducting
Background and purpose - Childhood fractures are associated with lower peak bone mass (a determinant of osteoporosis in old age) and higher adult fracture risk. By examining time trends in childhood fracture epidemiology, it may be possible to estimate the vector of fragility fracture risk in the future. Patients and methods - By using official inpatient and outpatient data from the county of Skån
The effect of intensive smoking cessation programs on postoperative complications has never before been assessed in soft tissue surgery when smoking cessation is initiated on the day of surgery.
Context. The Gaia-ESO Public Spectroscopic Survey will observe a large sample of clusters and cluster stars, covering a wide age-distance-metallicity-position-density parameter space. Aims. We aim to determine C, N, and O abundances in stars of Galactic open clusters of the Gaia-ESO survey and to compare the observed abundances with those predicted by current stellar and Galactic evolution models.
The purpose of this article is to examine the impact of organisational structure and hoteliers’ risk proclivity on innovativeness in the context of the Japanese hotel industry. Survey questionnaires were used to collect relevant data from 115 hotels in Japan. Using a multiple regression analysis, the antecedents of innovativeness in the hotel industry are been examined. The findings are mixed with
Chemical plasmid DNA (pDNA) gels were prepared by a cross-linking reaction with ethylene glycol diglycidyl ether (EGDE). Fluorescence microscopy (FM) and scanning electron microscopy (SEM) images of pDNA gels are reported. For the first time, the pDNA gels have been investigated with respect to their swelling in aqueous solution containing different additives, such as metal ions, polyamines, polyc
Popular Abstract in Uncoded languages Kronična upala je u podlozi mnogih bolesti modernog čovjeka kao što su djiabetes, astma, ateroskleroza itd. Upalu predvode različiti tkivni makrofagi. Proteini iz porodice galektina, proizvedeni u makrofagima, dodatno pridonose razvoju bolesti, stoga je od velikog interesa odgonetnuti različite funkcije galektina. Ovaj rad nastoji identificirati specifične uloContemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. The aim of this thesis was to pin-point specific galectin-3 roles in
Popular Abstract in Danish Summary in Danish Patientsikkerhed på hospital – forebyggelse af uventede dødsfald via systematisk anvendelse af et Early Warning Score system På hospitaler i den vestlige del af verden sker det, på trods af store indsatser for at øge patientsikkerheden, at indlagte patienters tilstand forværres alvorligt, og at nogle af disse patienter i værste tilfælde dør, som konsekAbstract In-hospital patient safety is at times hampered, leaving general ward patients at considerable risk of gradual, even life-threatening, deterioration. In many European clinical settings, inappropriate nursing practice of bedside monitoring and management has recently been addressed as impending to in-hospital patient safety. Vital parameters have for two decades been known to deviate in in
The "type" DeKalb mounds of northeastern Illinois, USA (42.0 degrees N, -88.7 degrees W), are formed of basal sand and gravel overlain by rhythmically bedded fines, and weathered sand and gravel. Generally from 2 to 7 m thick, the fines include abundant fossils of ostracodes and uncommon leaves and stems of tundra plants. Rare chironomid head capsules, pillclam shells, and aquatic plant macrofossi
Experimental models implicate protease activated receptors (PARs) as important sensors of the proteolytic tumor microenvironment during breast cancer development. However, the role of the major PARs, PAR-1 and PAR-2, in human breast tumors remains to be elucidated. Here, we have investigated how PAR-1 and PAR-2 protein expression correlate with established clinicopathological variables and patient
To improve population health, it is important to create environments that support activity, participation and health. One crucial aspect concerns the degree to which the built environment is accessible for all people including those with reduced functional capacity. The overarching objective of this thesis was to explore and further develop methodology for accessibility assessments based on the no
Current trends in industrial automation are the need for customizable production, vertical integration, more advanced sensors and actuators, and shorter time to market. The currently used control systems and languages for control were developed with a more static production in mind. More flexible languages and tools are needed to get a more flexible production. The flexible graphical programming l
Purpose – The purpose of this paper is to explore the relationship between sustainability adoption and internal legitimacy construction. Design/methodology/approach – The paper is designed as a critical inquiry into existing research and practice on sustainability adoption, illustrated by two corporate vignettes. Findings – Prior studies tend to assume that awareness raising is a sufficient means
Previous research has shown that a less positive emotional tone in adolescents’ relationships to parents, but not in their relationships to peers, predicts more of behaviour problems and substance use. The purpose of the present study was to replicate these findings, and to extend this research to deliberate self-harm. In a first study with a variable-oriented approach, correlations were analysed
We evaluated the antagonistic effects of newly identified lactic acid bacteria (LAB) in the genera Lactobacillus and Bifidobacterium, originating from the honey stomach, on the honey bee pathogen, Paenibacillus larvae. We used inhibition assays on agar plates and honey bee larval bioassays to investigate the effects of honey bee LAB on P. larvae growth in vitro and on AFB infection in vivo. The in
