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Background: Hemophilia B is a genetic bleeding disorder caused by a deficiency of clotting factor IX, which presents unique challenges in clinical management. Advances in therapeutic strategies for hemophilia B have significantly improved patient outcomes but have also necessitated ongoing education for healthcare professionals. This illustrated review provides an overview of the challenges and op
Two new endemic species from Bolivia, Gomphrena vallegrandensis T. Ortuño & S. Lozada-Gobilard and Gomphrena palmariensis T. Ortuño, J. Gutiérrez. & Montesinos, are described and illustrated. The former only occurs in the native open natural grassland close to the Tucuman forest (Prov. Vallegrande), and the latter is restricted to the areas with rock outcrops in the subpuna close to the in
The circular economy constitutes a paradigm shift which has proven to be both engaging and unrealistic. While scholars and practitioners have started to advocate for a move toward the circular economy, promising a full reconfiguration of underlying practices and processes, many have become disillusioned about the lack of traction and progress. The circular economy transition has fallen between uto
The package ParSeq is a Python software library for Parallel execution of Sequential data analysis. It implements a general analysis framework that consists of transformation nodes - intermediate stops along the analysis propagation to visualize data, display status and provide user input - and transformations that connect the nodes. ParSeq imports data into an adjustable data model - a collection
Obesity represents a global health challenge, with a critical and urgent need for long-term, sustainable management strategies. Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. At first approved for the treatment of type 2 diabetes mellitus, tirzepatide represents one of the latest clinically approved and commercia
In this paper, we study the function spaces D(μ) by Richter (1991) and Aleman (1993), and Dμ→ by Rydhe (2019). It is known that the forward shift Mz is bounded and expansive on D(μ), and therefore D(μ) coincides with a de Branges-Rovnyak space H[B]. We show that such a B is rational if and only if μ is finitely atomic, and this happens exactly when the corresponding defect operator has finite rank
This study examined Poles’ acculturation preferences profiles toward two groups: people from Ukraine and the Middle East, and their relation to perceived cultural distance. The study framework emphasizes the juxtaposition of media and political narratives surrounding migrants arriving in Poland. Representative data from 924 participants was analysed. Regarding the preference toward individuals fro
Glioblastoma (GBM), the most aggressive brain tumor in adults, is characterized by its infiltrative growth along the perivascular space. Mural cells (MCs), encompassing pericytes and smooth muscle cells, are multifunctional perivascular cells implicated in GBM progression. MCs not only facilitate vascular co-option but have also been suggested to contribute to the immunosuppressive tumor microenvi
In packaging, the structural integrity of paperboard under complex stresses is essential. This study examines the delamination behavior of paperboard under normal and shear loading modes, which are the base for developing mixed-mode models. Four commercial paperboard grades, sourced from fibers across three geographical regions, are investigated using Double Cantilever Beam (DCB) and Split Double
In light of the escalating global polycrisis—a convergence of environmental, social, and mental health crises—this paper explores the potential of mindfulness-based approaches for fostering human and planetary wellbeing and sustainability. We specifically investigate the linkages between Mindfulness-Based Stress Reduction (MBSR) and sustainability, and how they can be strengthened to support trans
Portable optically stimulated luminescence (pOSL) analysis allows rapid relative dating of sediments that potentially can be calibrated against known OSL ages to provide an age estimate for landforms across a large area. This study uses 186 pOSL measurements and 20 OSL ages to investigate the postglacial landscape evolution inside the Younger Dryas moraines in NE Finnmark and Finnish Lapland. Aeol
ImportanceThe management of complications following oral cavity squamous cell carcinoma (OCSCC) surgery can be challenging. Previous studies show conflicting results on complication risks after preoperative radiotherapy (RT), necessitating a randomized controlled trial (RCT).ObjectiveTo compare early complications during hospitalization for OCSCC surgery between patients receiving preoperative acc
Education for sustainability is widely recognised as a critical pathway for driving the transformations needed to address today’s polycrisis. Despite growing theoretical and conceptual advancements in sustainability education, current approaches have not achieved the deep systemic changes required. While university networks and individual institutions increasingly integrate sustainability into the
