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Clinical system for non-invasive in situ monitoring of gases in the human paranasal sinuses

We present a portable system for non-invasive, simultaneous sensing of molecular oxygen (O-2) and water vapor (H2O) in the human paranasal cavities. The system is based on high-resolution tunable diode laser spectroscopy (TDLAS) and digital wavelength modulation spectroscopy (dWMS). Since optical interference and non-ideal tuning of the diode lasers render signal processing complex, we focus on Fo

Effects of neurokinin receptor antagonists on L-dopa induced bladder hyperactivity in normal conscious rats.

PURPOSE: The urodynamic effects of intrathecal neurokinin (NK) receptor blockade on L-dopa-induced bladder hyperactivity were investigated in a rat model. MATERIALS AND METHODS: Continuous cystometry was performed in normal, conscious, female Sprague-Dawley rats. RESULTS: In rats pretreated with intraperitoneal carbidopa 50 mg./kg., intraperitoneal L-dopa 50 mg./kg. caused bladder hyperactivity th

Determining Heart Activity Present in the Pressure Sensors of a Dialysis Machine

Determination of heart status during dialysis can im- prove patient monitoring. Pressure sensors in the dialysis machine measures the heart pulses that propagates in the body and enter the extracorporeal blood circuit. A peri- staltic blood pump, located in the same circuit, introduces strong periodic pressure pulses that interfere with the much weaker cardiac component. These signal characteristi

Knee laxity after complete anterior cruciate ligament tear: a prospective study over 15 years.

There is limited knowledge of knee laxity in the long term after a complete anterior cruciate ligament (ACL) tear treated without ACL reconstruction. The aim of this study was (1) to describe the clinical course of knee laxity after a complete ACL tear over 15 years, and (2) to study the association between knee laxity and meniscal injuries and the development of knee osteoarthritis (OA). We studi

Reduced iNOS expression in adenoids from children with otitis media with effusion.

Granath A, Norrby-Teglund A, Uddman R, Cardell L-O. Reduced iNOS expression in adenoids from children with otitis media with effusion. Pediatr Allergy Immunol 2010: 21: 1151-1156. © 2010 John Wiley & Sons A/S Nitric oxide (NO) is a key mediator in the local immune response of human airways. Inducible NO-synthases (iNOS), and endothelial NO-synthases (eNOS) are two enzymes known to regulate its

Situated research and design for everyday life

This paper elaborates theoretical and methodological aspects of design processes in a disability context and aims to relate them to other sciences. It particularly emphasizes situated aspects of research: the need for being there, with the users in their

Gender differences in implicit moral orientation associations: The justice and care debate revisited

Employing new measures (Implicit Association Test) to study the classic issue of moral orientations, we predicted and found gender differences in implicit associations to the concepts of justice and care. Specifically, we found that men more strongly associate justice vs. care with importance and with themselves than women. However, participants’ explicit ratings did not reveal any clear patterns

Climbing Fiber Regulation of Spontaneous Purkinje Cell Activity and Cerebellum-Dependent Blink Responses(1,2,3).

It has been known for a long time that GABAergic Purkinje cells in the cerebellar cortex, as well as their target neurons in the cerebellar nuclei, are spontaneously active. The cerebellar output will, therefore, depend on how input is integrated into this spontaneous activity. It has been shown that input from climbing fibers originating in the inferior olive controls the spontaneous activity in