Intervening on modifiable risk factors to prevent dementia is of key importance, since progress-modifying treatments are not currently available. Education is inversely associated with dementia risk, but causality and mechanistic pathways remain unclear. We aimed to examine the causality of this relationship in Sweden using, as a natural experiment, data on a compulsory schooling reform that exten

Diagnostic imaging often outperforms the surgeon's ability to identify small structures during therapeutic procedures. Smart soft tissue markers that translate the sensitivity of diagnostic imaging into optimal therapeutic intervention are therefore highly warranted. This paper presents a unique adaptable liquid soft tissue marker system based on functionalized carbohydrates (Carbo-gel). The liqui

Speech is both dynamic and distinctive at the same time. This implies a certain contradiction which has entertained researchers in phonetics and phonology for decades. The present dissertation assumes that articulation behaves as a function of time, and that we can find phonological structures in the dynamical systems. EMA is used to measure mechanical movements in Swedish speakers. The results sh

Sociodemographic inequalities in the occurrence of low back pain (LBP) are well-studied. This study aimed to examine complex sociodemographic inequalities in the risk LBP consultation in the population from a socioeconomical intersectional perspective. Using register data, we identified 458,852 individuals aged 35-75 years residing in Skåne in 2013, with no previous LBP consultation since 2006. We

This book presents multidisciplinary research that expands our understanding of the innovation system (IS) and the entrepreneurial ecosystem (EE) perspectives on regional economic development. It critically reviews the two concepts and explores the promise and the limits of bridging IS and EE, particularly as applied outside of the bubbling global hubs or to the types of entrepreneurship different

This is an annotated checklist of all the recognized and named taxa of freshwater fishes in Iran. It documents recent changes and controversies in the nomenclature and includes primary synonyms updated from the Jouladeh-Roudbar et al. (2015b) checklist. We provide an updated comprehensive listing of taxonomy, diagnostic and meristic characters, names, and conservation status, including detailed di

This introductory chapter sets the scene for the book theme and presents the main book contributions and take-aways. It first briefly overviews the entrepreneurial ecosystems and the innovation systems frameworks focusing on their central topics, evolution and practical applications. It proceeds to highlight the ways the two concepts can (and in many cases should) learn from each other. This discu

The epilogue synthesizes the main conclusions from the book. Keeping practical applications in mind, it argues that the entrepreneurial ecosystems (EE) and the innovation systems (IS) frameworks can be enriched not only by cross-fertilization but also by extending to incorporate a range of underexplored issues and by being applied in unconventional contexts. The chapter concludes by highlighting s

In this short paper we introduce a research project currently underway exploring the industrial development, and accompanying socio-economic changes, in an industrial town in Sweden: Karlskoga. Here we consider specifically the confluence of factors and issues around economic development on the one hand, and population and migration on the other hand. We illustrate, through the Karlskoga case of a

The human Transient Receptor Potential A1 (hTRPA1) ion channel, also known as the wasabi receptor, acts as a biosensor of various potentially harmful stimuli. It is activated by a wide range of chemicals, including the electrophilic compound N-methylmaleimide (NMM), but the mechanism of activation is not fully understood. Here, we used mass spectrometry to map and quantify the covalent labeling in

Bio-based 5-hydroxymethylfurfural (5-HMF) and its derivatives have attracted enormous attention due to their valuable market potential. Production of pure 5-HMF is challenging owing to the high reactivity of its functional groups and formation of by-products. In this study, an efficient continuous process for 5-HMF production in a biphasic system and its recovery at high yield and selectivity was

We present a three-year multidisciplinary research project that started in 2019 and is funded by FORTE (Swedish Research Council for Health, Working Life and Welfare). The theoretical aim of the project is to gain a better understanding of the principles that underlie successful communication between the sighted and the blind via audio description (AD). The aim of a series of experiments is to ideWe present a three-year multidisciplinary research project that started in 2019 and is funded by FORTE (Swedish Research Council for Health, Working Life and Welfare). The theoretical aim of the project is to gain a better understanding of the principles that underlie successful communication between the sighted and the blind via audio description (AD). The aim of a series of experiments is to ide

Climate change has the potential to alter hydrological regimes and to expand saturated areas in permafrost environments, which are important sources of organic carbon. The sources, transfer zones, and delivery mechanisms of carbon into the stream network are controlled by the morphometric properties of the catchment; however, the utility and limitations of these properties as predictors of dissolv

Streptococcus pneumoniae is a major cause of community acquired pneumonia and septicaemia in humans. These diseases are frequently associated with thromboembolic cardiovascular complications. Pneumococci induce the exocytosis of endothelial Weibel-Palade Bodies and thereby actively stimulate the release of von Willebrand factor (VWF), which is an essential glycoprotein of the vascular hemostasis.

In this thesis I conducted numerical simulations to study the flow behavior of dense particle flows composed of hard particles under planar shear using the discrete element method. The simulations were carried out in two dimensional systems, where the particles are modelled as circular discs. The discs are non-Brownian and neutrally buoyant. The granular flows can be either dry or immersed in a Ne