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Clinical frailty scale – skörhet är ett sätt att skatta biologisk ålder

The term frailty denotes a multi-dimensional syndrome characterised by reduced physiological reserves and increased vulnerability. Frailty may be used as a marker of biological age, distinct from chronological age. There are several instruments for frailty assessment. The Clinical Frailty Scale (CFS) is probably the most commonly used in the acute care context. It is a 9-level scale, derived from

The Chick Embryo As A Model to Study The Initiation And Growth Of Neuroblastoma

Neuroblastoma is pediatric cancer of the sympathetic nervous system which originates from the trunk neural crest cell population during embryonic development. Clinical representation of neuroblastoma ranges from a spontaneous regression to metastatic disease with only about 50% survival rate. Molecular events which turn normal development of sympathetic nervous system to tumorigenic has not been f

The European Spallation Source neutrino super-beam conceptual design report

A design study, named $${\text {ESS}}\nu {\text {SB}}$$for European Spallation Source neutrino Super Beam, has been carried out during the years 2018–2022 of how the 5 MW proton linear accelerator of the European Spallation Source under construction in Lund, Sweden, can be used to produce the world’s most intense long-baseline neutrino beam. The high beam intensity will allow for measuring the neuA design study, named ESSνSB for European Spallation Source neutrino Super Beam, has been carried out during the years 2018–2022 of how the 5 MW proton linear accelerator of the European Spallation Source under construction in Lund, Sweden, can be used to produce the world’s most intense long-baseline neutrino beam. The high beam intensity will allow for measuring the neutrino oscillations nea

Invasive Streptococcal Infection Can Lead to the Generation of Cross-Strain Opsonic Antibodies

The human pathogen Streptococcus pyogenes causes substantial morbidity and mortality. It is unclear if antibodies developed after infections with this pathogen are opsonic and if they are strain specific or more broadly protective. Here, we quantified the opsonic-antibody response following invasive S. pyogenes infection. Four patients with S. pyogenes bacteremia between 2018 and 2020 at Skåne Uni

Core Lab Adjudication of the ACURATE neo2 Hemodynamic Performance Using Computed-Tomography-Corrected Left Ventricular Outflow Tract Area

(1) Background: Hemodynamic assessment of prosthetic heart valves using conventional 2D transthoracic Echocardiography-Doppler (2D-TTE) has limitations. Of those, left ventricular outflow tract (LVOT) area measurement is one of the major limitations of the continuity equation, which assumes a circular LVOT. (2) Methods: This study comprised 258 patients with severe aortic stenosis (AS), who were t

Distriktssköterskors erfarenheter och upplevelser av att arbeta med psykisk ohälsa hos äldre personer inom hemsjukvård under COVID-19 pandemin

Bakgrund: Under COVID-19 pandemin rekommenderades äldre personer att isolera sig från andra människor då denna grupp hade störst risk att drabbas av svår sjukdom och död till följd av COVID-19. Till följd av dessa rekommendationer ökade den psykiska ohälsan bland äldre personer. Distriktssköterskan har en nyckelroll för att identifiera psykisk ohälsa men det saknas kunskap om hur distriktsskötersk

Comparing the efficacy of algorithmic approaches to the functional annotation of proteins in Trichomonad parasites

How useful are algorithms when studying the genetics of non-model organisms? Metamonada is a group of eukaryotic single-celled organisms called protists that live in different environments using varied metabolic pathways. One unifying characteristic of the supergroup is their incredibly functionally reduced mitochondria. This group of organisms is worth studying because they are a mixture of free

Distriktsköterskors och Sjuksköterskors erfarenheter av följsamhet till basala hygientuiner i hemsjukvården innan och under Covid-19 pandemin.

Bakgrund: Distriktssjuksköterskan i hemsjukvården har en stor utmaning och ansvar att förhindra att äldre patienter som är mer känsliga för att drabbas av infektioner till följd av bristande hygien. Tidigare studier beskriver brister i följsamheten av basala hygienrutiner i hemsjukvården. Under den första vågen av Covid-19 pandemin var det äldre sårbara människor som drabbades i högsta grad av all

Möten mellan distriktssköterskor och patienter när ett gemensamt språk saknas

Språkförbistringar i vårdmötet påverkar distriktssköterskan, patienten och anhöriga i patientmötet. Studier om distriktssköterskors perspektiv på vårdmötet är begränsad, dessutom har tidigare forskning främst studerat fenomenet inom slutenvården. Syftet med studien var att belysa distriktssköterskans perspektiv av mötet mellan patient och distriktssköterska när de inte talar samma språk. Det utför