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Free testing of Flow Induced Dispersion Analysis now at LP3

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 29 October 2024 LP3 now has a demo unit of Fidabio (Fida Neo instrument) for Flow Induced Dispersion Analysis for protein sample quality, which is available for evaluation purposes the next 3 months. The analysis of sample gives an indication of the protein's health, oligomeric state/complex formation, if it

https://www.lp3.lu.se/article/free-testing-flow-induced-dispersion-analysis-now-lp3 - 2025-02-21

LP3 at the first SciLifeLab Lund retreat

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 18 November 2024 Four of LP3’s staff participated in the first SciLifeLab Lund retreat in Båstad, 14 to 15th November 2024 with the theme: “Achieving Excellence Together”. The retreat was focused on giving the staff from all SciLifeLab site platforms the opportunity to get to know each other through presenta

https://www.lp3.lu.se/article/lp3-first-scilifelab-lund-retreat - 2025-02-21

Cell-free protein synthesis workshop January 2025

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 21 November 2024 The Swedish NMR Centre in Gothenburg will host a workshop on cell-free protein synthesis, with special focus on applications in NMR spectroscopy. The workshop, which is held in Gothenburg 21-23 Jan 2025 will entail both lectures and practical wet lab work. The idea is that participants bring

https://www.lp3.lu.se/article/cell-free-protein-synthesis-workshop-january-2025 - 2025-02-21

Open post-doctoral position at ESS and Lund University

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 4 December 2024 Do you have strong competence in neutron reflectometry and cancer membrane models? Then this is a great opportunity for you! It's a 3-year MSCA position for research in lipid interactions in cancer involving cell membrane imaging using neutron scattering techiques, with focus on detecting cha

https://www.lp3.lu.se/article/open-post-doctoral-position-ess-and-lund-university - 2025-02-21

Welcome to SciLifeLab seminars!

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 21 January 2025 SciLifeLab Lund, which Lp3 is part of, arranges interesting seminars with presentations of its different units and local core facilities together with user presentations. So please take the opportunity to learn more of our different services which could be useful in you research. The SciLifeL

https://www.lp3.lu.se/article/welcome-scilifelab-seminars - 2025-02-21

LP3 at the 36th MAX IV user meeting

By cob-ars [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 23 January 2025 LP3 was presented at the yearly meeting for MAX IV synchrotron users held in January 2025. Dr. Celeste Sele presented two posters about LP3's capabilities within protein crystallisation/biophysics and structure determination as well as protein production within the national research infrastructure Protein

https://www.lp3.lu.se/article/lp3-36th-max-iv-user-meeting - 2025-02-21

Heads up! Next P4EU meeting will be in Gothenburg 25th-27th August 2025!

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 17 February 2025 You don't want to miss this! PPS is hosting, and more info on registration will come later! Please follow our PPS linkedin for releases of the preliminary program and registration details-coming soon.Alternatively, see www.pps.gu.se/en or www.p4eu.org For urgent enquiries please contact e-ma

https://www.lp3.lu.se/article/heads-next-p4eu-meeting-will-be-gothenburg-25th-27th-august-2025 - 2025-02-21

Collaborative research project on corona virus proteins

Published 18 July 2020 3D structure of Nsp10 from the new corona virus SARS-cov-2. An international collaboration between the Lund Protein Production Platform (LP3), the UCL School of Pharmacy and ESS, through its DEMAX platform, has initiated biophysical and structural studies of three non-structural proteins from the novel coronavirus, SARS CoV-2, the causative agent of COVID-19. Recently we man

https://www.lp3.lu.se/article/collaborative-research-project-corona-virus-proteins - 2025-02-21

FragMAX awarded funding from the Swedish Research council

Published 29 March 2019 FragMAX, a project run in collaboration between LP3, MAXIV, Astra Zeneca and SARomics Biostructures, has been awarded funding from the Swedish Research Council. The project aims to establish a fragment based screening facility, enabling scientists and small companies to screen low molecular weight fragments for binding to target proteins using X-ray crystallography.Read mor

https://www.lp3.lu.se/article/fragmax-awarded-funding-swedish-research-council - 2025-02-21

Renewal of beamtime access at BioMAX and allocated time at SciLifeLab Cryo-EM facility

Published 31 December 2018 LP3 was successful in its application for renewal of beamtime access at BioMAX (the X-ray macromolecular crystallography beamline of MAX IV). The protein structure pipeline at LP3 is now established. Users can get their protein samples crystallised and the resulting crystals can on a regular basis be evaluated for diffraction and data can be collected. Processing of X-ra

https://www.lp3.lu.se/article/renewal-beamtime-access-biomax-and-allocated-time-scilifelab-cryo-em-facility - 2025-02-21

More for Less: Low-Cost, High-Yield Protein Deuteration for Neutron Crystallography

Published 30 December 2018 A team from the Lund Protein Production Platform, Karolinska Institute, and the European Spallation Source have published an optimized approach to high-yield protein deuteration at low cost, for neutron protein crystallography in Archives of Biochemistry and Biophysics (external website). 

https://www.lp3.lu.se/article/more-less-low-cost-high-yield-protein-deuteration-neutron-crystallography - 2025-02-21

Baculovirus-driven protein expression in insect cells: A benchmarking study

Published 29 December 2018 The baculovirus-insect cell expression system has become one of the most widely used eukaryotic expression systems for heterologous protein production in many laboratories. To date, limited data has been presented in the literature to benchmark the protocols used for baculovirus vectors, and this study facilitates the selection of a system for optimal production of targe

https://www.lp3.lu.se/article/baculovirus-driven-protein-expression-insect-cells-benchmarking-study - 2025-02-21

Beamtime at BioMAX

Published 28 December 2018 LP3 has been granted beamtime at the X-ray macromolecular crystallography beamline of MAX IV, BioMAX. This allows users to have their crystals rapidly evaluated for diffraction. With funding from BioCARE (a governmental supported strategic research area in cancer (external website)) the Lund Protein Production Platform, LP3, can also offer the possibility to process data

https://www.lp3.lu.se/article/beamtime-biomax - 2025-02-21

Protein Production Network Sweden launches new website

Published 30 December 2017 The Lund Protein Production Platform is one of several protein production facilities in Sweden that form the Protein Production Network Sweden (PPNS), each with its own specialties and focus. PPNS is an informal network formed in 2013 between protein production facilities at Swedish universities. The overall aim is to make competence and protein production methodologies

https://www.lp3.lu.se/article/protein-production-network-sweden-launches-new-website - 2025-02-21

Partnership between LP3 and DEMAX

Published 29 December 2017 The DEuteration and MAcromolecular Xtallization (DEMAX) platform of the European Spallation Source ERIC (ESS) moved into Biology House A at Lund University and is now co-localized with the Lund Protein Production Platform (LP3). DEMAX (external website) and LP3 are collaborating to coordinate their efforts to develop cost-effective production of deuterated biomaterials (

https://www.lp3.lu.se/article/partnership-between-lp3-and-demax - 2025-02-21

Protein Production Network Sweden pilot expression screen completed

Published 30 December 2014 LP3 is part of the Protein Production Network Sweden (PPNS) that aims to make multiple protein expression hosts, methodologies and competence in protein production available to the Swedish academic life science community. Collaboration between Swedish protein production sites is crucial in order to solve complex scientific questions and in a pilot effort to test a new jo

https://www.lp3.lu.se/article/protein-production-network-sweden-pilot-expression-screen-completed - 2025-02-21

A network of Swedish protein production facilities

Published 30 December 2014 LP3 is taking part in the formation of a network of Swedish protein production facilities together with Protein Science Facility at Karolinska Institutet/SciLifeLab (external website) Mammalian Protein Expression at Göteborg University (external website) Protein Expertise Platform at Umeå University (external website) Drug Discovery and Development platform at SciLifeLab

https://www.lp3.lu.se/article/network-swedish-protein-production-facilities - 2025-02-21