Literature on familial risk of carcinomas in situ (CISs) is limited because many cancer registries do not collect information on CIS. In Sweden CISs are collected, and we used these data to analyze familial relative risks (RRs) for concordant (CIS-CIS) types of anogenital (cervical, other female and male genital and anal) and skin squamous cell CIS; additionally RRs were assessed between CIS types

Plasma accelerators present one of the most suitable candidates for the development of more compact particle acceleration technologies, yet they still lag behind radiofrequency (RF)-based devices when it comes to beam quality, control, stability and power efficiency. The Horizon 2020-funded project EuPRAXIA ("European Plasma Research Accelerator with eXcellence In Applications") aims to overcome t

We hope to design a study on the development of a course on our master’s program. The course has been developed over two years in order to address two fundamental problems in the ten year old program: students from Asian and African countries were often unable to complete the program. The hitch seemed to be writing and discussing in an independent, critical and reflective way. The aim of this semi

Många vill nu överge överskottsmålet i det finanspolitiska ramverket. Men det är riskfyllt. Efter den internationella finanskrisen 2008 saknade många länder med hög statsskuld utrymme för en tillräckligt expansiv finanspolitik och tvingades till den hårda åtstramningspolitik som ligger bakom de populistiska strömningarna i Europa, skriver Fredrik N G Andersson och Lars Jonung.

Inkludering har kommit att betraktas som ett viktigt egenvärde i politiska sammanhang. Inkluderande samhällen ses som progressiva och välfungerande. Exkludering och exkluderande praktiker anses däremot påverka samhället negativt. Men kan det vara så att inkludering är bra i många sammanhang men inte i alla? Och är möjligtvis det som brukar betraktas som inkluderingens motsats, exkludering, i vissa

The Copenhagen Food Coop (CFC) is an alternative food community in Copenhagen that provides locally grown organic vegetables and fruits to its members. It also disseminates knowledge on organic and sustainable food production, distribution, and consumption and aims to develop a participatory and inclusive community organisation. Some scholars see such alternative food networks as having great pote

Black hole binary systems with companion stars are typically found via their x-ray emission, generated by interaction and accretion. Noninteracting binaries are expected to be plentiful in the Galaxy but must be observed using other methods. We combine radial velocity and photometric variability data to show that the bright, rapidly rotating giant star 2MASS J05215658+4359220 is in a binary system

Co-housing is an emerging housing form in Spain, where many pioneering initiatives are found in Catalonia and the Barcelona area. Using the La Borda project as a recurring illustration, but also drawing on other examples and developments, the chapter seeks to contextualize this nascent but noticeable interest in co-housing in and around Barcelona. Starting at the scale of the crisis-ridden Spanish

The development of Pt(IV) anticancer prodrugs to overcome the detrimental side effects of Pt(II)-based anticancer drugs is of current interest. The kinetics and reaction mechanisms of the reductive activation of the carboplatin Pt(IV) prodrug cis,trans-[Pt(cbdca)(NH3)2Cl2] (cbdca = cyclobutane-1,1-dicarboxylate) by the major small-molecule reductants in human plasma were analyzed in this work. The

The report draws on socio-legal theory in relation to growing concerns over fairness, accountability and transparency of societally applied artificial intelligence (AI) and machine learning. The purpose is to contribute to a broad socio-legal orientation by describing legal and normative challenges posed by applied AI. To do so, the article first analyses a set of problematic cases, e.g. image rec

The ecology and biogeochemistry of lakes in the subarctic region are particularly sensitive to changes in the abundance and optical properties of dissolved organic matter (DOM). External input of colored DOM to these lakes is an extensively researched topic, but little is known about potential reciprocal feedbacks between the optical properties of DOM and internal microbial processes in the water.

“Garden phlox ‘Alma Jansson’ comes from a smallholding in Roslagen. It has been on the farm at least since 1939 when Stina Jansson moved in. It was her mother-in-law, Alma Jansson, who took care of the plants in the garden. ‘Everything comes from Grandma. She had such beautiful flowers’, said Stina. We do not know where she received or bought this variety, but it was not newly planted in 1939.” Th

Amyloid fibril formation is a hallmark of neurodegenerative disease caused by protein aggregation. Oligomeric protein states that arise during the process of fibril formation often coexist with mature fibrils and are known to cause cell death in disease model systems. Progress in this field depends critically on development of analytical methods that can provide information about the mechanisms an

Objective: To estimate inappropriate opioid dispensing in patients with knee or hip osteoarthritis (OA) defined as (1) dispensing of opioids within the first year of diagnosis or (2) long-term opioid use. Design: Data from Skåne Healthcare Register was linked with the Swedish Prescribed Drug Register. Incidence proportion of dispensed opioids within first year of incident knee or hip OA diagnosis