The interaction between nitrogen monoxide (NO) and organic peroxy radicals (RO2) greatly impacts the formation of highly oxygenated organic molecules (HOM), the key precursors of secondary organic aerosols. It has been thought that HOM production can be significantly suppressed by NO even at low concentrations. Here, we perform dedicated experiments focusing on HOM formation from monoterpenes at l

Interferons (IFNs) are secreted cytokines with the ability to activate expression of IFN stimulated genes that increase resistance of cells to virus infections. Activated transcription factors in conjunction with chromatin remodelers induce epigenetic changes that reprogram IFN responses. Unexpectedly, 8-oxoguanine DNA glycosylase1 (Ogg1) knockout mice show enhanced stimuli-driven IFN expression t

This article presents a search for new resonances decaying into a Z or W boson and a 125 GeV Higgs boson h, and it targets the νν¯ bb¯ , ℓ+ℓ−bb¯ , or ℓ±νbb¯ final states, where ℓ = e or μ, in proton-proton collisions at s = 13 TeV. The data used correspond to a total integrated luminosity of 139 fb−1 collected by the ATLAS detector during Run 2 of the LHC at CERN. The search is conducted by examin

Introduction: Treatment persistence is a proxy for efficacy, safety and patient satisfaction, and a switch in treatment or treatment discontinuation has been associated with increased indirect and direct costs in inflammatory arthritis (IA). Hence, there are both clinical and economic incentives for the identification of factors associated with treatment persistence. Until now, studies have mainly

Cities need to take swift action to deal with the impacts of extreme climate events. The co-production of positive visions offers the potential to not only imagine but also intervene in guiding change toward more desirable urban futures. While participatory visioning continues to be used as a tool for urban planning, there needs to be a way of comparing and evaluating future visions so that they c

I want to suggest that it would be bad if compatibilism were true, and that this gives us good reason to think that it isn't. This is, you might think, an outlandish argument, and the considerable burden of this paper is to convince you otherwise. There are two key elements at stake in this argument. The first is that it would be - in a distinctive sense to be explained - bad if compatibilism were

The first measurements of elliptic flow of π ±, K ±, p + p ¯ , KS0 , Λ + Λ ¯ , ϕ, Ξ −+ Ξ ¯ + , and Ω −+ Ω ¯ + using multiparticle cumulants in Pb–Pb collisions at sNN = 5.02 TeV are resented. Results obtained with two- (v 2{2}) and four-particle cumulants (v 2{4}) are shown as a function of transverse momentum, p T, for various collision centrality intervals. Combining the data for both v 2{2} and

Emerging studies suggest a correlation between elevated plasma homocysteine (hcy) levels and the risk of atherosclerosis, vascular disorders, and neurodegenerative diseases, including Parkinson's disease (PD). This narrative review delves into the intricate relationships between Hcy, vitamin B metabolites, dopamine-substituting compounds, and various symptoms of PD. Patients undergoing a long-term

This chapter overviews migration management across Africa, arguing with Vigneswaran and Quirk (2015) that postcolonial African states prevent, promote, and channel migration for myriad political and economic purposes. While breaking from Eurocentric bias obsessed with Africa to Europe migration, we balance the view of African states not as dysfunctional European prototypes, nor as incomparable and

Background: Chondrocytes are the primary cells responsible for maintaining cartilage integrity and function. Their role in cartilage homeostasis and response to inflammation is crucial for understanding the progression and potential therapeutic interventions for various cartilage-related disorders. Developing an accessible and cost-effective model to generate viable chondrocytes and to assess thei

Immersing a user in life-like extended reality (XR) scenery using a head-mounted display (HMD) with a constrained form factor and hardware complexity requires remote rendering on a nearby edge server or computer. Millimeter-wave (mmWave) communication technology can provide sufficient data rate for wireless XR content transmission. However, mmWave channels exhibit severe sparsity in the angular do

Background: In microscopic colitis (MC), the incidence has increased over the last decades. The aim of the present study was to determine the incidence of lymphocytic (LC) and collagenous colitis (CC) in the county Skåne (Scania), southern Sweden, during the period 2010–20 with focus both on the temporal and spatial variations. Methods: The MC diagnosis was retrieved from the biopsy registries at

Aim: We aimed to describe clinical practices and criteria for discharge of very preterm infants in Nordic neonatal units. Methods: Medical directors of all 89 level-2 and level-3 units in Denmark, Finland, Iceland, Norway and Sweden were invited by e-mail to complete a web-based multiple-choice survey with the option to make additional free-text comments. Results: We received responses from 83/89

Children continue to experience harm when undergoing clinical procedures despite increased evidence of the need to improve the provision of child-centred care. The international ISupport collaboration aimed to develop standards to outline and explain good procedural practice and the rights of children within the context of a clinical procedure. The rights-based standards for children undergoing te

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of brain regions. This approach, first, disregards the exquisite spatial detail manifested by fMRI due to working on average regional activities, se

Ultralow-temperature refrigeration faces significant issues linked to the security of the cold chain for the production, storage, transportation, and distribution of COVID-19 vaccines. The use of environmentally friendly refrigerants in cascade refrigeration systems (CRS) to provide low-temperature range is motivated by the high demand for ultralow-temperature refrigeration units. In the current s