Electrification of many industries using off-road high power machines presents several problems. In order to analyse the viability of different solutions the logistics, machine operation and power management have to be analysed. In this paper a model is presented that in a novel way combines these problems into a complete system model that can be optimized on several levels. Complex charging schem

Borrowing hydrogen (BH) reactions are very useful for the sustainable synthesis of C−C and C−N bonds. They generally operate with transition metal-based catalysts along with stoichiometric/catalytic amounts of added base. Here we report that two catalytic transformations, generally carried out with the BH methodology, i. e. N-alkylation of amines with alcohols and β-alkylation of secondary alcohol

The extent to which genetic variations contribute to interindividual differences in weight loss and metabolic outcomes after bariatric surgery is unknown. Identifying genetic variants that impact surgery outcomes may contribute to clinical decision making. This review evaluates current evidence addressing the association of genetic variants with weight loss and changes in metabolic parameters afte

Precision cancer medicine is a multidisciplinary team effort that requires involvement and commitment of many stakeholders including the society at large. Building on the success of significant advances in precision therapy for oncological patients over the last two decades, future developments will be significantly shaped by improvements in scalable molecular diagnostics in which increasingly com

Agricultural extension, or advisory services, have a key role to play in supporting farmers’ learning and adoption of new practices and technologies. This paper analyses gaps and needs which require addressing in order for extension systems to more effectively contribute to the upscaling of ecological intensification approaches in East African smallholder agriculture. Our starting point is the pus

Background: Fibrotic atrial cardiomyopathy plays an important role in determining the outcome of ablation in patients with atrial fibrillation (AF). Two main methods are being used for the evaluation of fibrosis: voltage-based high-density (HD) electroanatomical mapping (EAM) and late gadolinium enhancement MRI (LGE-MRI). The comparability between both methods in detecting fibrosis has not been sy

We consider Toeplitz determinants whose symbol has: (i) a one-cut regular potential, (ii) Fisher-Hartwig singularities and (iii) a smooth function in the background. The potential is associated with an equilibrium measure that is assumed to be supported on the whole unit circle. For constant potentials, the equilibrium measure is the uniform measure on the unit circle and our formulas reduce to we

The field of (im)politeness studies has been steadily growing and developing but the role of conventionality and the type of semiotic system (e.g., language vs. gesture) for impoliteness perception has not been sufficiently explored. We used a cognitive-semiotic framework combining a reaction-time experiment and in-depth interviews with sixty participants to explore how Russian and Swedish native

COVID-19 was first identified in Wuhan City in December 2019 and spread throughout Hubei Province and other parts of China. After causing significant morbidity and mortality in China, by February 2020, it had spread to numerous other countries, infecting millions of people and causing a large number of deaths across the world. The COVID-19 pandemic put a burden on almost all areas of the world inc

Epidemics and pandemics are associated with a variety of life-threatening conditions and have serious effects on physical as well as mental wellbeing. The Covid-19 pandemic raised the same difficulties for public and private sectors including schools, businesses, healthcare sectors, etc. The disease, which originated in Wuhan, China in December 2019, has ravaged nearly every country in the world.

Background/Objective: Growth and obesity have been associated with increased risk of islet autoimmunity (IA) and progression to type 1 diabetes. We aimed to estimate the effect of energy-yielding macronutrient intake on the development of IA through BMI. Research Design and Methods: Genetically at-risk children (n = 5,084) in Finland, Germany, Sweden, and the USA, who were autoantibody negative at

Mitral valve prolapse (MVP) is a heart valve disease that is often familial, affecting 2%–3% of the general population. MVP with or without mitral regurgitation can be associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD). Research on familial MVP has specifically focused on genetic factors, which may explain the heritable component of the disease estimated to

In this work, we consider the problem of estimating the directions of arrival of far-field sources impinging on a sensor array using a computationally efficient approach. A novel adaptive grid selection technique is employed to reduce the dimensionality of the used dictionary matrix. The method further makes use of a SPICE-inspired dictionary to adaptively select an appropriate regularization para

BACKGROUND: Early conduct problems and school failure are prominent risk factors for several adverse outcomes in later life. With the potential of reaching many children at early stages of their life, school-based interventions constitute a valuable approach to universal prevention. Good behavior game (GBG) is a promising school-based behavior management program, having shown immediate reductions

This is the ninth yearly article in the Tourette Syndrome Research Highlights series, summarizing selected research reports from 2022 relevant to Tourette syndrome. The authors briefly summarize reports they consider most important or interesting.

We formulate a version of the low-scale Majoron model equipped with an inverse seesaw mechanism featuring lepton-number preserving dimension-6 operators in the scalar potential. Contrary to its dimension-4 counterpart, we find that the model can simultaneously provide light and ultralight Majorons, neutrino masses and their mixing, while featuring strong first-order cosmological phase transitions