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Acute myeloid leukemia in patients we judge as being older and/or unfit

Definition of older age in AML is arbitrary. In the context of the clinical studies, it starts with age ≥ 60 or ≥65 years and in recent years ≥70 or 75, depending on the selection of the studied population. In clinical practice, with older age we often mean that the patient is unfit for intensive chemotherapy. Higher age overlaps with categories such as worse performance status, unfitness, co-morb

Improved low-frequency performance of cross-laminated timber floor panels by informed material selection

The paper demonstrates improved structural low-frequency vibroacoustic performance of cross-laminated timber (CLT) floor panels by informed selection of the wood material. The use of wood species and strength classes that are not traditionally assigned to CLT panels was investigated in order to study their influence on dynamic characteristics and vibroacoustic response metrics. The potential of ea