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NSAID visar övertygande effekt vid postoperativ smärta

Non-steroidal antiinflammatory drugs (NSAID) are increasingly being included in the management of postoperative pain as part of a multimodal therapeutic approach. However, there is an ongoing debate among clinicians as to the perioperative use of NSAID's as many authors have cautioned against their use in this setting. Concerns about their impact on coagulation and renal function as well as a risk

Lactobacilli attenuate bacteremia and endotoxemia associated with severe intra-abdominal infection

Background. Systemic administration of antibiotics or selective decontamination is frequently used in the prophylaxis and treatment of infections originating from the gastrointestinal flora. In this study, we wanted to compare. the protective effect of enteral administration of lactobacilli to gentamicin against severe intra-abdominal infection. Methods. Male Sprague Dawley rats underwent cecal li

Photoinduced ultrafast dynamics of Ru(dcbpy)(2)(NCS)(2)-sensitized nanocrystalline TiO2 films: The influence of sample preparation and experimental conditions

In most of the previous ultrafast electron injection studies of Ru(dcbpy)(2)(NCS)(2)-sensitized nanocrystalline TiO2 films, experimental conditions and sample preparation have been different from study to study and no studies of how the differences affect the observed dynamics have been reported. In the present paper, we have investigated the influence of such modifications. Pump photon density, e

Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes

Anti-C1q autoantibodies are present in sera of patients with several autoimmune diseases, including systemic lupus erythematosus (SLE). Strikingly, in SLE the presence of anti-C1q is associated with the occurrence of nephritis. We have generated mouse anti-mouse C1q mAb's and used murine models to investigate whether anti-C1q autoantibodies actually contribute to renal pathology in glomerular immu

Health-related quality of life and radiographic vertebral fracture

Background: Vertebral fractures are associated with back pain and disability; however, relatively little is known about the impact of radiographic vertebral fractures on quality of life in population samples. The aim of this study was to determine the impact of a recent radiographic vertebral fracture on health-related quality of life (HRQoL). Methods: Men and women aged 50 years and over were rec

In-vivo effects of endothelin-1 and ETA receptor blockade on arterial, venous and capillary functions in skeletal muscle

Results from in vitro studies have indicated that endothelin-1 is a main candidate for endothelium-derived contracting factors. The aim of this in vivo study was to describe in quantitative terms the effects of endothelin-1 (ET-1), and of ETA receptor blockade, on vascular tone (resistance) in large-bore arterial resistance vessels (> 25 microns), small arterioles (< 25 microns) and the veins, as

Calculation of glomerular filtration rate expressed in mL/min from plasma cystatin C values in mg/L

The Cockcroft-Gault formula is often used to calculate the glomerular filtration rate (GFR) from plasma creatinine results. In Sweden this calculation is not usually done in the laboratory, but locally in the wards. These manual calculations could cause erroneous results. In several studies plasma cystatin C has been shown to be superior to plasma creatinine for estimation of GFR. One limitation o

Breaking the boundaries of careers. A study of the mobility effects of a program for career councelling

In this paper a study of a career planning project launched by the Swedish National Tax Board is reported. The project, named Propeller, was initiated in 1998 as a joint endeavour among three agencies: the Swedish National Tax Board, the Regional Stockholm Tax Office and the Enforcement Authority. The intention was to create a common micro labour market in order to encourage employees to become mo

Klimatdata för fuktberäkningar - Fuktsäkerhet i byggnader

Syftet med denna skrift är att exemplifiera hur man kan välja klimatdata för olika beräkningar som bör genomföras vid en fuktdimensionering. Klimatparametrarna finns sammanställda i ett PC-program som heter KLIMATDATA. Programmet är fritt tillgängligt att hämta hem. Värdena på de olika klimatparametrarna är sammanställda från tio olika meteorologiska mätstationer i Sverige för 30-årsperioden 1961-

Galerkin/Runge-Kutta discretizations of nonlinear parabolic equations

Global error bounds are derived for full Galerkin/Runge-Kutta discretizations of nonlinear parabolic problems, including the evolution governed by the p-Laplacian with p >= 2. The analysis presented here is not based on linearization procedures, but on the fully nonlinear framework of logarithmic Lipschitz constants and an extended B-convergence theory. The global error is bounded in L-2 by Delta