Published 29 December 2018 The baculovirus-insect cell expression system has become one of the most widely used eukaryotic expression systems for heterologous protein production in many laboratories. To date, limited data has been presented in the literature to benchmark the protocols used for baculovirus vectors, and this study facilitates the selection of a system for optimal production of targe

https://www.lp3.lu.se/article/baculovirus-driven-protein-expression-insect-cells-benchmarking-study - 2025-01-09

Published 28 December 2018 LP3 has been granted beamtime at the X-ray macromolecular crystallography beamline of MAX IV, BioMAX. This allows users to have their crystals rapidly evaluated for diffraction. With funding from BioCARE (a governmental supported strategic research area in cancer (external website)) the Lund Protein Production Platform, LP3, can also offer the possibility to process data

https://www.lp3.lu.se/article/beamtime-biomax - 2025-01-09

Published 30 December 2017 The Lund Protein Production Platform is one of several protein production facilities in Sweden that form the Protein Production Network Sweden (PPNS), each with its own specialties and focus. PPNS is an informal network formed in 2013 between protein production facilities at Swedish universities. The overall aim is to make competence and protein production methodologies

https://www.lp3.lu.se/article/protein-production-network-sweden-launches-new-website - 2025-01-09

Published 29 December 2017 The DEuteration and MAcromolecular Xtallization (DEMAX) platform of the European Spallation Source ERIC (ESS) moved into Biology House A at Lund University and is now co-localized with the Lund Protein Production Platform (LP3). DEMAX (external website) and LP3 are collaborating to coordinate their efforts to develop cost-effective production of deuterated biomaterials (

https://www.lp3.lu.se/article/partnership-between-lp3-and-demax - 2025-01-09

Published 30 December 2016 A Bioscreen C system for microbiological growth studies is now available at LP3. The Bioscreen C (external website) can incubate, shake, and measure the turbidity (OD) of up to 200 samples simultaneously. 

https://www.lp3.lu.se/article/new-system-microbiological-growth-monitoring - 2025-01-09

Published 30 December 2014 LP3 is part of the Protein Production Network Sweden (PPNS) that aims to make multiple protein expression hosts, methodologies and competence in protein production available to the Swedish academic life science community. Collaboration between Swedish protein production sites is crucial in order to solve complex scientific questions and in a pilot effort to test a new jo

https://www.lp3.lu.se/article/protein-production-network-sweden-pilot-expression-screen-completed - 2025-01-09

Published 30 December 2014 LP3 is taking part in the formation of a network of Swedish protein production facilities together with Protein Science Facility at Karolinska Institutet/SciLifeLab (external website) Mammalian Protein Expression at Göteborg University (external website) Protein Expertise Platform at Umeå University (external website) Drug Discovery and Development platform at SciLifeLab

https://www.lp3.lu.se/article/network-swedish-protein-production-facilities - 2025-01-09

Published 29 December 2014 Right now LP3 is in the process of establishing the Baculovirus Expression Vector System (BEVS) – a system for expression of recombinant proteins in insect cells. This system will complement the current LP3 capabilities to express proteins in bacteria and yeast. The BEVS, being a eukaryotic expression system, has its strength in producing proteins from higher eukaryotic

https://www.lp3.lu.se/article/eukaryotic-expression-system - 2025-01-09

Published 25 March 2021 Under den pågående CoViD-19 pandemin har förståelsen för virusets proteiner varit en central del i forskningen om SARS-CoV-2, eftersom det är genom proteinkontakter som viruset invaderar människans celler. På flera universitet i Sverige finns faciliteter som producerar proteiner för olika forskningsprojekt och som ingår i ett nätverk kallat Protein Produktion Sverige (PPS).

https://www.lp3.lu.se/article/med-proteiner-som-nycklar-till-sars-cov-2-sa-har-vi-lart-oss-mer-om-viruset - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 25 October 2021 By fragment screening using x-ray crystallography we identified four ligands revealing ligand-binding sites in conserved interfaces between SARS-CoV-2 nsp10 and nsp14/nsp16. The nsp14/10 interaction is weak and therefore could be disrupted by small molecules. In a collaborative effort, the Lu

https://www.lp3.lu.se/article/fragmax-library-identifies-ligand-binding-sites-nsp10-and-nsp1416-interfaces-sars-cov-2 - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 25 October 2021 The new protein production platform will start in the beginning 2022 and is a co-operation between five Swedish universities. A new nationally distributed infrastructure - Protein Production Sweden or Proteinproduktion Sverige (PPS) in Swedish, will start up in the beginning of 2022. This is

https://www.lp3.lu.se/article/new-national-infrastructure-protein-production-sweden-pps - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 12 April 2022 LP3 extends its portfolio of machines available for biophysical analysis by welcoming the OMNISEC system from Malvern Panalytical. Thanks to a grant from Olle Engkvisits foundation to Prof. Anders Malmström (Experimental Medical Sciences, Lund University), we now host a state of the art multi-d

https://www.lp3.lu.se/article/now-lp3-absolute-molecular-weight-determination-proteins - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 5 December 2022 Wolfgang Knecht, head of LP3 presented the capabilities of LP3 in biophysics and protein structure determination at the first Swedish national PI-meeting in Biochemistry, Biophysics and Molecular Biology (external webpage). The meeting was jointly organized by the Swedish Society for Biochemi

https://www.lp3.lu.se/article/lp3-presented-swedish-national-pi-meeting-biochemistry-biophysics-and-molecular-biology - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 20 January 2023 To strengthen the engagement of the Swedish scientific community in ESS, Sweden has now officially become part of the ESS in-kind community with four projects selected by ESS and the Swedish Research Council. To strengthen the engagement of the Swedish scientific community in the European Spa

https://www.lp3.lu.se/article/sweden-enters-kind-agreement-ess-lp3-contributes-deuteration-lab-services - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 5 April 2023 The Deuteration Network (DeuNet) is an international network which aims to facilitate access to deuteration services. The Deuteration Network (DeuNet) (external webpage) is an international network of deuteration facilities and laboratories which aims to facilitate access to deuteration services

https://www.lp3.lu.se/article/new-deunet-webpage-now-launched - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 4 October 2023 All staff from LP3, which is one out of five nodes in the PPS national infrastructure, participated. The distributed national research infrastructure Protein Production Sweden (PPS, https://pps.gu.se/en, external webpage) did meet for its second annual staff retreat at Ljunglöfska slottet in S

https://www.lp3.lu.se/article/annual-pps-retreat-stockholm - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 23 October 2023 Recently, a book chapter with protocols for the Baculovirus Expression Vector System in insect cells was published by LP3. Lund Protein Production Platform (LP3) has recently published its standard operating procedures for recombinant protein expression using the Baculovirus Expression Vector

https://www.lp3.lu.se/article/new-publication-about-bevs-lp3 - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 7 November 2023 Members of the board and scientific committee of PPS, Sabine Suppmann and Kim Remans, respectively are among the authors of a new review in Star Protocols about expression systems for recombinant protein production. The overview is based on a survey with 60 leading experts in protein producti

https://www.lp3.lu.se/article/guide-choosing-expression-system-recombinant-proteins - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 20 December 2023 Lund Protein Production Platform (LP3) is featured in EUGLOHRIA Talks and EUGLOHRIA Virtual Tours approaching audiences with interactive and innovative content and an interview with the head of LP3, Dr. Wolfgang Knecht, is now available on the EUGLOHRIA homepage. The European University Alli

https://www.lp3.lu.se/article/lund-protein-production-platform-featured-euglohria-talks-and-euglohria-virtual-tours - 2025-01-09

By anna [dot] rasmussen [at] biol [dot] lu [dot] se (Anna Andersson Rasmussen) - published 17 January 2024 At the first 2024 management meeting, SciLifeLab Lund welcomed LP3 as a new local core facility. The aim of the local SciLifeLab sites in Umeå, Linköping, Gothenburg and Lund is to bring national infrastructure activities closer to the research communities at these locations, and to contribut

https://www.lp3.lu.se/article/lp3-newest-local-core-facility-scilifelab-lund - 2025-01-09