Published 30 June 2016 Researchers at Lund University in Sweden have discovered that the appetite hormone CART is regulated by glucose and is found in greater quantity in people with type 2 diabetes. “This could be the body’s own defence mechanism to lower blood sugar levels in case of type 2 diabetes”, says Associate Professor Nils Wierup, in charge of the study. The study shows that the appetite

https://www.ludc.lu.se/article/antidiabetic-effects-discovered-appetite-hormone-cart - 2025-03-06

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 3 July 2024 Jan Nilsson's research group has identified a substance that stimulates the repair capacity and growth of vascular cells. Biomedical analyst Filiz Serifler has contributed to the project. Photo: Petra Olsson Heart attack and stroke are common complications of diabetes, as the body's ability to repair and form v

https://www.ludc.lu.se/article/new-peptide-may-reduce-risk-diabetes-complications - 2025-03-06

By press [at] med [dot] lu [dot] se (The Faculty of Medicine at Lund University) - published 19 July 2024 An international consortium presents new guidelines that may increase the clinical relevance of precision medicine research. Photo: istock.com/xubingruo Precision medicine seeks to reduce errors and improve accuracy in medical and health recommendations, but better evidence is needed to fulfil

https://www.ludc.lu.se/article/new-guidelines-aim-increase-accuracy-precision-medicine-research - 2025-03-06

By noomi [dot] egan [at] fsi [dot] lu [dot] se (Noomi Egan) - published 19 September 2024 Åke Lernmark's studies of diabetes-related autoantibodies have contributed to increasing knowledge about type 1 diabetes so that it may become possible to start screening children for the disease. Photograph: Kennet Ruona During his more than 50-year career, diabetes researcher Åke Lernmark has made several s

https://www.ludc.lu.se/article/scientist-who-paving-way-screening-type-1-diabetes - 2025-03-06

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 10 December 2024 Isabel Gonçalves and Andreas Edsfeldt have analysed atherosclerotic plaques from patients who have type 2 diabetes and patients who do not have the disease. Photo: Petra Olsson People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis.

https://www.ludc.lu.se/article/new-explanation-dangerous-atherosclerotic-plaques-type-2-diabetes - 2025-03-06

By anna [dot] hellgren [at] med [dot] lu [dot] se (Anna Hellgren) - published 24 October 2024 Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. Photo: iStock/Suriyawut Suriya Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers

https://www.ludc.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-03-06

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 1 November 2024 Joao Duarte's research group is investigating how the brain is affected by diabetes. Photograph: Petra Olsson Diabetes researcher Joao Duarte specialices in studying what happens in the brain in diabetes. In his research, he is also investigating how diet changes can improve brain function in connection wit

https://www.ludc.lu.se/article/praised-research-diabetes-and-dementia - 2025-03-06

By petra [dot] olsson [at] med [dot] lu [dot] se (Petra Olsson) - published 5 November 2024 Research nurse Jessica Melin takes as blood sample from a participant. Åke Lernmark, principal investigator of the TEDDY study in Sweden, gives examples of important lessons from the study in the video. In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, F

https://www.ludc.lu.se/article/new-knowledge-about-type-1-diabetes-large-scale-teddy-study-will-soon-be-completed - 2025-03-06

By Olle [dot] dahlback [at] med [dot] lu [dot] se (Olle Dahlbäck) - published 17 February 2021 A recent study indicates that there is a correlation between the number of people spend on the internet and problematic and addictive games. Photo: Mostphotos Low age, the number of hours spent on the internet/social media, feelings of loneliness and thoughts about seeking treatment for mental illness. A

https://www.medicine.lu.se/article/study-screen-games-mental-illness-and-addiction - 2025-03-06

By Agata [dot] Garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 3 March 2021 Mikael Dolsten, the celebrated head of research at Pfizer and visiting professor of Pharmacology at the Faculty of Medicine, tells the story of how his company developed a COVID-19 vaccine in just nine months. Photo: Agata Garpenlind. It’s Friday night in Lund and soon Mikael Dolsten, acclaimed head of

https://www.medicine.lu.se/article/our-visiting-professor-tells-astonishing-story-vaccine-can-save-world-pandemic - 2025-03-06

By olle [dot] dahlback [at] med [dot] lu [dot] se (Olle Dahlbäck) - published 15 March 2021 Lars Edvinsson. Foto: Tove Smeds In the early 1970s, Lars Edvinsson stepped through the doors of Lund University for the first time. More than 50 years later, he is awarded the world's most prominent prize in brain research, "The Brain Prize", which is awarded annually by the Lundbeck Foundation. He receive

https://www.medicine.lu.se/article/migraine-pioneer-awarded-prestigious-brain-prize - 2025-03-06

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 15 March 2021 The structure of an antibody. In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers at Lund University in Sweden have developed a new, efficient method based on the genetic scissors CRISPR-Cas9, that facilitates antibody development. The

https://www.medicine.lu.se/article/new-method-facilitates-development-antibody-based-drugs - 2025-03-06

Published 21 January 2021 Countries with the highest burden of maternal and newborn deaths and stillbirths often have little information on these deaths. Since over 81% of births worldwide now occur in facilities, using routine facility data could reduce this data gap. We assessed the availability, quality, and utility of routine labour and delivery ward register data in five hospitals in Banglade

https://www.lupop.lu.se/article/labour-and-delivery-ward-register-data-availability-quality-and-utility-every-newborn-birth - 2025-03-06

Published 21 January 2021 We reweighted the Malmö Diet and Cancer (MDC) study based on population register data on background variables, including socio-demographics and hospital admissions for both participants and the background population. Following individuals from baseline in 1991-1996 and at most until 2016, we studied mortality (all-cause, cancer, and CVD), incidences (cancer and CVD), and

https://www.lupop.lu.se/article/can-validity-cohort-be-improved-reweighting-based-register-data-evidence-swedish-mdc-study - 2025-03-06

Published 9 April 2018 A project jointly conducted by the Nordic national statistical institutes and funded by NordForsk was initiated in 2015. The project, Nordic Microdata Access Network (NordMAN), seeks to establish a single pan-Nordic solution to facilitate researchers' access to the Nordic metadata compiled for statistical purposes, and to provide an overview of the existing Nordic registers.

https://www.lupop.lu.se/article/nordman-facilitates-researchers-access-nordic-microdata-and-provides-metadata-existing-nordic - 2025-03-06

Published 22 January 2021 Data from population-based cancer registries are often used to compare cancer survival between countries or regions. The ICBP SURVMARK-2 study is an international partnership aiming to quantify and explore the reasons behind survival differences across high-income countries. However, the magnitude and relevance of differences in cancer survival between countries have been

https://www.lupop.lu.se/article/exploring-impact-cancer-registry-completeness-international-cancer-survival-differences-simulation - 2025-03-06

Published 22 January 2021 We propose combining population-based register data with a nested clinical cohort to correct misclassification and unmeasured confounding through probabilistic quantification of bias. We have illustrated this approach by estimating the association between knee osteoarthritis and mortality. We used the Swedish Population Register to include all persons resident in the Skån

https://www.lupop.lu.se/article/probabilistic-quantification-bias-combine-strengths-population-based-register-data-and-clinical-0 - 2025-03-06

Published 22 January 2021 Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009– 2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, with

https://www.lupop.lu.se/article/validity-intracerebral-hemorrhage-diagnoses-danish-patient-registry-and-danish-stroke-registry - 2025-03-06

Published 22 January 2021 Participants are members of the Maccabi Health Services, 40–65 years of age, with exquisitely detailed laboratory, medical diagnoses and medication data available in the Maccabi electronic medical records since 1998. Data collected through IRAP include genetic, sociodemographic, cognitive, brain imaging, lifestyle, and health-related characteristics at baseline and every

https://www.lupop.lu.se/article/israel-registry-alzheimers-prevention-irap-study-design-and-baseline-characteristics - 2025-03-06

Published 23 January 2021 Large prospective cohort studies may offer an opportunity to study the etiology and natural history of rare cancers. Cancer diagnoses in observational cohort studies are often self-reported. Little information exists on the validity of self-reported cancer diagnosis, especially rare cancers, in Canada. This study evaluated the validity of self-reported cancer diagnosis in

https://www.lupop.lu.se/article/importance-cancer-registry-linkage-studying-rare-cancers-prospective-cohorts - 2025-03-06