By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 14 December 2022 In substantia nigra, neurons expressing Calretinin seem to be more resistant to damage. Photo: Lautaro Belfiori. MultiPark’s new special interest groups (SIGs) address essential scientific and technological needs and provide opportunities for professional development and network formation to our yo

https://www.multipark.lu.se/article/molecular-signaling-neurodegenerative-disorders-special-interest-group - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 13 January 2023 Keivan Javanshiri defends his thesis 20 January 2023. Profile photo:Tove Smeds. Keivan Javanshiri’s Ph.D. project explores cardiac and vascular pathologies in Lewy body dementia and Alzheimer's disease. January 20, he defends his thesis. Here, he shares the most important findings and why sudden car

https://www.multipark.lu.se/article/cognitive-disease-beyond-brain-phd-interview-keivan-javanshiri - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 21 December 2022 We ended the MultiPark year in December as we started it in January: with a MultiPark Retreat! The December retreat was our first big meeting IRL after the pandemic, and it turned out to be a much appreciated event. Thank you to all participants, and thank you once again to the retreat organizing c

https://www.multipark.lu.se/article/multipark-closing-circle-2022-and-looking-forward-2023 - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 10 January 2023 Katrine Skovgård defends her thesis 19 January 2023. Katrine Skovgård’s Ph.D. project sheds light on the dysfunctions in the brain through which dopaminergic pharmacotherapies for Parkinson’s disease affect motor behaviors. January 19, she defends her thesis. She explains how better experimental mod

https://www.multipark.lu.se/article/why-dopamine-receptor-type-matters-phd-interview-katrine-skovgard - 2025-01-07

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 12 January 2023 Dopamine-producing neurons that researchers from Lund University have grown in the laboratory from human embryonic stem cells. Photo: Agnete Kirkeby. At the end of October 2022, the Swedish Medical Products Agency gave the go-ahead for a clinical trial of the stem cell-based therapy STEM-PD for the treatment of

https://www.multipark.lu.se/article/nerve-cells-could-transform-treatment-parkinsons - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 3 February 2023 Elna Dickson defends her thesis 17 February 2023. Huntington's disease is known as the "dance disease" due to the patient's characteristic motor symptoms. However, Elna Dickson's Ph.D. project shows that the disease also leads to pathological changes outside the brain. February 17, she defends her t

https://www.multipark.lu.se/article/huntingtons-metabolic-dysfunctions-phd-interview-elna-dickson - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 10 February 2023 Tomas Roos defends his thesis 17 February 2023. The aggregation of the protein Amyloid-beta (Abeta) into plaques outside the nerve cells has been recognized in patients with Alzheimer’s disease since 1905. But eliminating the plaques has not helped patients so far. Still, Tomas Roos thinks that Abe

https://www.multipark.lu.se/article/does-alzheimers-disease-start-inside-neurons-phd-interview-tomas-roos - 2025-01-07

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 28 February 2023 The milestone transplant was performed at Skåne University Hospital in February. On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund University and it is now being tested in

https://www.multipark.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-01-07

By press [at] liu [dot] se (Mikael Sönne) - published 8 March 2023 With the injectable gel the researchers were able to grow electrodes in living tissue. Here it is tested on a microfabricated circuit. Photo: Thor Balkhed/Linköpings universitet The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully

https://www.multipark.lu.se/article/electrodes-grown-brain - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 20 March 2023 Kajsa Brolin defends her thesis 27 March 2023. Photo: Kennet Ruona Kajsa Brolin explores how our genes and environment affect the risk of developing Parkinson’s disease. March 27, she defends her Ph.D. project partly based on MultiPark’s biobank sample collection. Here, she tells about the newly disco

https://www.multipark.lu.se/article/genes-and-environment-pd-phd-interview-kajsa-brolin - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 13 March 2023 After a decade of protocol development and preparations, MultiPark researchers have finally launched the clinical trial. Recently, dopamine-producing cells generated from embryonic stem cells were transplanted into the first Parkinson's patient at Skåne University Hospital. During the autumn 2022, the

https://www.multipark.lu.se/article/stem-pd-bench-bedside-story-multipark-researchers-0 - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 16 March 2023 Looking for the next step in your career? In need of some scientific inspiration? Or are you just curious about what MultiPark´s senior researchers are doing and their professional journey? Listen to MultiPark’s new podcast series “Meet our scientists”! In a newly launched podcast, young MultiPark res

https://www.multipark.lu.se/article/meet-our-scientists-new-podcast-young-multipark-researchers - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 April 2023 Behind the ongoing clinical trials are years of basic research in the lab where the new generation of researchers continues where the previous one handed over. Photo: Kenneth Ruona. In the early 1950s, no one knew what caused Parkinson's disease. Then, Arvid Carlsson's discovery of dopamine opened the

https://www.multipark.lu.se/article/world-parkinsons-day-transplantations-parkinsons-disease-time-travel - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 28 March 2023 Genetics are one of the keys to understanding neurodegenerative disease. That is why MultiPark researchers with expertise in genetics gather across research groups. Genetics of neurodegenerative diseases is a new special interest group (SIG) addressing scientific and technological needs to unravel the

https://www.multipark.lu.se/article/genetics-neurodegenerative-diseases-special-interest-group - 2025-01-07

By katrin [dot] stahl [at] med [dot] lu [dot] se (Lund University) - published 13 April 2023 Sara Linse and Oskar Hansson. Three researchers at Lund University, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. Two of them are MultiPark research leaders. They do resea

https://www.multipark.lu.se/article/double-success-multipark-research-groups-prestigious-eu-grant-round - 2025-01-07

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 17 May 2023 Several Nobel laureates, renowned scientists, and successful biotech entrepreneurs are coming to Lund in May to participate in the Lund Spring Symposium, an international pharmaceutical symposium sponsored by MultiPark. Sarah Tabrizi, a high profile Huntington researcher, and some of MultiPark's own researc

https://www.multipark.lu.se/article/superstars-coming-lund-pharmaceutical-symposium-sponsored-multipark - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 29 May 2023 A 7 Tesla MRI of a human brain. Picture: Tekla Kylkilahti, Lundgaard group. Recent studies indicate that acquired brain injuries, such as traumatic brain injury, trigger potentially harmful responses that may lead to neurodegenerative pathology. “Acquired brain injuries and their links to neurodegenerat

https://www.multipark.lu.se/article/acquired-brain-injuries-special-interest-group - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 7 June 2023 Thanks to the recent development of diagnostic tools based on blood biomarkers linked to Alzheimer’s, it is possible to predict whether an individual will develop the disease. Therefore, MultiPark researchers gather across groups to investigate hidden opportunities and develop implementable tools also f

https://www.multipark.lu.se/article/fluid-biomarkers-special-interest-group - 2025-01-07

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 2 June 2023 Microglial immune cells around the area of a human embryonic stem cell transplant to treat Parkinson’s Disease in a rat brain. In April, the young MultiPark working group organized a photo competition entitled "Brain in Picture". The external jury has had a hard time choosing, but now, they have appoint

https://www.multipark.lu.se/article/brain-picture-winning-photo - 2025-01-07

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 27 June 2023 Postdoctoral researcher Vivien Horvath investigates X-Linked Dystonia-Parkinsonism (XDP), a rare neurodegenerative disorder. New research is underway at Lund University, led by Dr. Vivien Horvath, a postdoctoral researcher at Lund Stem Cell Center. Supported by a new grant from the Collaborative Center for

https://www.multipark.lu.se/article/exploring-role-jumping-genes-x-linked-dystonia-parkinsonism - 2025-01-07