Våra celler kommer ihåg SARS-CoV-2 Hjärt- och kärlsjukdomar är en av de ledande dödsorsakerna i världen. Ateroskleros, ett tillstånd där fett ansamlas i kärlen, har visats orsaka hjärt- och kärlsjukdomar. Flera delar av vårt immunförsvar har även visats ha ett samband med ateroskleros. En av dessa delar är det adaptiva immunförsvaret, där så kallade B- och T-celler finns. B- och T-celler ingår iAdaptive immunity has been implicated in cardiovascular diseases, but the relationship between immune capacity or immune function in these diseases has yet to be established. I optimized a method to screen for immune capacity using immune responsiveness against the SARS-CoV-2 spike protein as a proxy. This method screens for markers upregulated during activation on lymphocytes using fluorescent an

Children of prisoners have increasingly been touted as the silent victims of incarceration due to the emotional and mental distress that often occurs following a parent's incarceration. Unfortunately, these children have not been met with much academic interest in Iceland. This thesis thus seeks to provide insight into how parental incarceration affects children in Iceland. Here, the character

Bakgrund Fysisk aktivitet är ett effektivt sätt att undvika flera negativa konsekvenser som ett stillasittande liv kan leda till. Under det senaste årtiondet har stillasittande hos universitetsstudenter ökat mer jämfört med unga vuxna generellt. För att utföra en handling eller förändring av en livsstil krävs motivation som kan grunda sig i inre eller yttre vinning. Syfte Syftet med studien var at

Människor som drabbats av stroke eller traumatiska hjärnskador (TBI) får ofta balanssvårigheter som kan påverka aktivitet och delaktighet negativt. Mini-Balance Evaluation Systems Test (Mini-BESTest) är ett mätinstrument som kan användas för att utvärdera balansförmågan, men dess reliabilitet och validitet är inte helt klarlagt efter stroke och TBI. Syfte Syftet med studien var att undersöka inter

Diabetic peripheral neuropathy (DPN) is a serious complication of diabetes, where skin biopsy assessing intraepidermal nerve fiber density (IENFD) plays an important diagnostic role. In vivo confocal microscopy (IVCM) of the corneal subbasal nerve plexus has been proposed as a noninvasive diagnostic modality for DPN. Direct comparisons of skin biopsy and IVCM in controlled cohorts are lacking, as

BACKGROUND: Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disabling stroke or death. Comparison of their long-te

BACKGROUND: Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in

Capturing how organizations build and maintain long-term and mutual beneficial relationships with influencers is an urgent quest by both, communication practitioners and scholars. In the ever-evolving context of digitalization, navigating influencer communication remains to be a major challenge, as the concept of an authentic partnership is constantly adapting in the fast-paced social media realm.

The purpose of this thesis was to analyze how disinformation narrative techniques are applied by actors during an organizational crisis to construct a narrative about Sweden. To achieve this goal, a qualitative content analysis method has been utilized on Twitter posts. By applying disinformation narrative techniques, the study examined which narrative techniques were used to link a public organiz

This paper is the first exhaustive investigation of a single kanji component: the ito element. Although, this element generally refers to thread or textile, the study examined this relationship and found a strong relationship to silk, cocoons, and craft—particularly weaving. A surprising find was the connection to dyeing/colour, which might not be obvious to the average student of Japanese. Moreov

Yatsu has both been described as an ‘abusive’ version of the nominaliser mono, as well having properties not shared with mono. In this paper, the Japanese nominaliser yatsu was examined using the written corpus Balanced Corpus of Contemporary Written Japanese (BCCWJ) created by the National Institute for Japanese Language and Linguistics (NINJAL). The research questions were as follows: “To what e

Context: Software selection in large-scale software development continues to be ad hoc and ill-structured. Previous proposals for software component selection tend to be technology-specific and/or do not consider business or ecosystem concerns.Objective: Our main aim is to develop an industrially relevant technology-agnostic method that can support practitioners in making informed decisions when s

Denna uppsats har diskuterat hur man i ett socialt fält samlar in kulturellt kapital och framförallt hur vingårdar inom det svenska vinlandskapet använder sig av renhet, smak och exklusivitet för att samla kulturellt kapital. Uppsatsen visar att man kan generera status och respekt genom att ha högt fokus på socialt och ekologisk hållbarhet inom produktionen och i kommunikationen mot sina gäste

BACKGROUND: Clinical Record (CR) writing is a fundamental skill for healthcare professionals, but the best e-learning methods for teaching it remain unstudied. Therefore, we investigated speech therapy students' differences in the quality production of CR at the placement and their experience after following asynchronous or synchronous e-learning courses.METHODS: A multi-method randomised controll

Background: Predicting a challenging clot when performing mechanical thrombectomy in acute stroke can be difficult. One reason for this difficulty is a lack of agreement on how to precisely define these clots. We explored the opinions of stroke thrombectomy and clot research experts regarding challenging clots, defined as difficult to recanalize clots by endovascular approaches, and clot/patient f

This article examines the functions of feminism in the critical reception of Kristina Sandberg’s Maj-Trilogy, published 2010-2014. Detailing the evaluative patterns of reviews, it is shown that critics’ increased attention to feminist politics and women’s history in the novels was tied to a de-aestheticizing rhetoric, exemplifying gender hierarchies on the literary field. However, the trilogy’s cr

Rökextrakt och dess negativa påverkan på återvinningsprocesser i lungceller från KOL-patienter Kroniskt obstruktiv lungsjukdom (KOL) är en global folksjukdom och den tredje största dödsorsaken i världen. Den kan kopplas till en mängd andra sjukdomar och tillstånd som också ofta ökar risken för att utveckla KOL, t ex hög ålder, kardiovaskulära och neurosjukdomar. Men den största och mest välkända Chronic obstructive pulmonary disease (COPD) is the third largest cause of death worldwide, with its most prominent risk factor being inhalation of smoke and pollutants. In this project, we studied two processes that are involved in COPD: autophagy and cellular senescence. Using primary human bronchial epithelial cells (HBECs) from healthy and COPD donors, we aimed to show that cigarette smoke ext