Background: Atherosclerotic plaque ruptures, triggered by blood flow–associated biomechanical forces, cause most myocardial infarctions and strokes. Objectives: This study aims to investigate the exact location and underlying mechanisms of atherosclerotic plaque ruptures, identifying therapeutic targets against cardiovascular events. Methods: Histology, electron microscopy, bulk and spatial RNA se

This paper discusses the relationship between the Sustainable Development Goals (SDGs) and the long-standing human rights system of the United Nations. Thematically, these two modes of global governance strongly overlap. Several SDGs are in line with human rights obligations. At the same time, the SDGs and human rights are based on divergent logics and constructed very differently. After capturing

The Syrian civil war has been described as a first example of the conflicts expected in the wake of climate change. The conflict, which started in 2011, was preceded by a severe drought in 2007–2009 that hit agriculture and the rural population hard. But what do we really know about what happened to Syria’s climate and agriculture before and after the start of the conflict? In this article, I summ

Public transport systems in different parts of the world are currently undergoing a change characterised by the introduction of battery-powered electric buses in everyday operations. The introduction of electric buses brings new challenges such as high investment costs and technology concerns, as well as new forms of collaboration between both established and new actors. The aim of this paper is t

The medial temporal lobe (MTL) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as Alzheimer's disease neurofibrillary tau tangles. The MTL cortex is composed of several subregions which differ in their functional and cytoarchitectonic features. As neuroanatomical schools rely on different cytoarchitectonic definition

A piece of lead with imprints from a coin die and the early minting in Lund. At an archaeological excavation in central Lund in the early 1970s a very unusual find was retrieved: a piece of lead with several imprints from a coin die. The motif and the runic inscription on the lead plate indicate that the die derives from Sven Estridsen’s minting during his late years as king of Denmark. The find i

We apply the statistical sparse jump model, a recently developed, interpretable and robust regime-switching model, to infer key features that drive the return dynamics of the largest cryptocurrencies. The algorithm jointly performs feature selection, parameter estimation, and state classification. Our large set of candidate features are based on cryptocurrency, sentiment and financial market-based

Perovskite solar cells (PSCs) have demonstrated rapid advancements in power conversion efficiency (PCE) in recent years, reaching 25.7% within a decade. However, the stability of PSCs lags behind in comparison, with short lifetimes being a major obstacle to commercialization. The various layers and interfaces within PSCs play a significant role in both PCE and stability. Spiro-OMeTAD is the most c

Lead halide perovskites (LHPs) photoelectrodes for photoelectrochemical (PEC) water splitting are promising candidates for solar-to-fuel conversion. However, the poor stability of LHPs in aqueous electrolyte media, together with the toxicity of lead, restricts the practical application of LHP photoelectrodes. Herein, we report the first-ever colloidal synthesis of quaternary Cu1.4Ag0.6BiI5 nanocry

As the adverse impacts of hydrological extremes increase in many regions of the world, a better understanding of the drivers of changes in risk and impacts is essential for effective flood and drought risk management and climate adaptation. However, there is currently a lack of comprehensive, empirical data about the processes, interactions, and feedbacks in complex human-water systems leading to

We coordinate interconnected agents where the control input of eachagent is limited by the control input of others. In that sense, the sys-tems have to share a limited resource over a network. Such problems canarise in different areas and it is here motivated by a district heating ex-ample. When the shared resource is insufficient for the combined needof all systems, the resource will have to be s

BACKGROUND: Patients with chronic respiratory failure treated with long-term oxygen therapy (LTOT) often have severe breathlessness, impaired exercise performance, and high but variable mortality that is difficult to predict. We aimed to evaluate breathlessness and exercise performance upon starting LTOT as predictors of overall and short-term mortality.METHODS: This was a longitudinal, population