With the move to a hydrogen-based primary steel production envisioned for the near future in Europe, existing regional industrial clusters loose major assets. Such a restructuring of industries may result in a new geographical distribution of the steel industry and also to another quality of vertical integration at sites. Both implications could turn out as drivers or barriers to invest in new tec

The wall flameholder is one of the credible alternatives to realize pilot ignition in augmented/ramjet combustors. To overcome the ablation for a long-term operation, two types of jet cooling, external-inhaled air and pressure-driven jet cooling, are proposed for the wall flameholder. In this work, the flow and combustion process in a laboratory scale rig is studied for different cooling schemes a

In recent years, the Icelandic dairy product skyr has been transformed from an everyday staple to a national food heritage. Skyr is high in protein and low in fat, and its nutritional value accounts for its international success. However, the domestic and international marketing of skyr glide effortlessly from medieval literature to modern healthy living in promoting skyr as a unique, wholesome, a

Marine reptiles constitute a diverse group of secondarily aquatic tetrapods that have inhabited the world’s oceans for the greater part of the last 250 million years. While certain large-scale anatomical changes have been observed through progressive alterations of their skeletal morphology (e.g., the evolution of fin-like limbs), little is known about those changes that have occurred in the integ

Warmer or cooler spring in northern high latitudes will, for the most part, directly impact gross primary productivity (GPP) of ecosystems, but also carry consequences for the upcoming seasonal GPP. Spatiotemporal patterns of these legacy effects are still largely unknown but important for improving our understanding of how plant phenology is associated with vegetation dynamics. In this study, imp

Background: Whole-body bone scintigraphy is a clinically useful non-invasive and highly sensitive imaging method enabling detection of metabolic changes at an early stage of disease, often earlier than with conventional radiologic procedures. Bone scintigraphy is one of the most common nuclear medicine methods used worldwide. Therefore, it is important that the examination is implemented and perfo

The favorable pharmacokinetics of MMC, used during intraperitoneal chemotherapy, has been reported in several studies [11-19]. A major safety issue in studies using intraperitoneal chemotherapy perfusion is the resulting systemic drug exposure. The AUCplasma is determined by the dose, the clearance, and the fraction absorbed from the peritoneal cavity. The reported mean plasma peak concentrations

Background: HIPEC has been proposed as an addition in the treatment of ovarian cancer. The purpose of this review was to evaluate the evidence and use of HIPEC after cytoreductive surgery as up-front therapy for inpatients with primary ovarian cancer. Methods: We performed a search on PubMed and Web of Science. Additional studies were identified by cross-referencing past reviews and published stud

A 54-year-old male with colorectal cancer was treated with cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC) because of peritoneal carcinomatosis. A left hemicolectomy was performed with creation of a colostomy and closure of rectal stump and two more small bowel resections. Postoperative course was complicated by anastomotic leakage, following two r

Background and objectives For unresectable peritoneal carcinomatosis (PC) median overall survival (OS) is 5-6 months. This article analyzes patients with PC from colorectal cancer (CRC) uneligible for debulking and hyperthermic intra-peritoneal chemotherapy, describing patient-and tumor-related factors possibly affecting survival. Patients and Methods From 2005 to 2009, 43 patients presented with

Introduction: The treatment of peritoneal carcinomatosis is based on cytoreduction followed by hyperthermic intraperitoneal chemotherapy and combined with adjuvant chemotherapy. In 2003, a randomized trial was finished comparing systemic chemotherapy alone with cytoreduction followed by hyperthermic intraperitoneal chemotherapy and systemic chemotherapy. This trial showed a positive result favorin

Convergent evidence associates exposure to endocrine disrupting chemicals (EDCs) with major human diseases, even at regulation-compliant concentrations. This might be because humans are exposed to EDC mixtures, whereas chemical regulation is based on a risk assessment of individual compounds. Here, we developed a mixture-centered risk assessment strategy that integrates epidemiological and experim

Infective endocarditis (IE) is a serious infection of the inner surface of heart, resulting from minor lesions in the endocardium. The damage induces a healing reaction, which leads to recruitment of fibrin and immune cells. This sterile healing vegetation can be colonized during temporary bacteremia, inducing IE. We have previously established a novel in vitro IE model using a simulated IE vegeta

OBJECTIVES: To investigate and characterize the influence of sex, age, muscle strength, and cardiovascular fitness on manual lifting patterns using exposure variation analysis (EVA) during a full working day among blue-collar workers.METHODS: Muscular activity (surface electromyography [sEMG]) of the thigh, low-back, and shoulder was measured throughout the working day in 173 employees with manual

Previous research has paid little attention to the multiple meanings of the concept of forest restoration. To gain a more comprehensive view of forest restoration, this paper compares the US forest restoration debate of the 1940s and 1990s, in the disciplines of ecology and forestry. The paper focuses on historical approaches to pasts and futures, and on “sociotechnical imaginaries” providing soci

Den antiamerikanska vänstern har fått en märklig ny sängkamrat efter Rysslands invasion av Ukraina: den ”realistiska” skolan inom internationella relationer, företrädd av den amerikanske professorn John Mearsheimer. Detta trots att realismen visat sig usel som prognosverktyg och att tron på den starkes rätt över den svage är något som annars brukar leda till protester – åtminstone mot USA, skriverDen antiamerikanska vänstern har fått en märklig ny sängkamrat efter Rysslands invasion av Ukraina: den ”realistiska” skolan inom internationella relationer, företrädd av den amerikanske professorn John Mearsheimer. Detta trots att realismen visat sig usel som prognosverktyg och att tron på den starkes rätt över den svage är något som annars brukar leda till protester – åtminstone mot USA, skriver

Boken är en analys av den normandiska erövringen av England, med fokus på slaget vid Hastings, men med utförliga redogörelser för tiden före och efter drabbningen.

Context: Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. Objectives: To evaluate the reliability and validity of symptom self-report in cancer outpatients with and without mild to moderate cognitive impairment. Methods: This was an analysi

Tissue turnover, especially in the skin, is altered in systemic sclerosis (SSc), leading to tissue accumulation. The objective was to examine type III, IV, and VI collagens turnovers in SSc and investigate longitudinal alterations in relation to modified Rodnan Skin Score (mRSS). We included patients fulfilling the 2013 ACR/EULAR criteria for SSc (limited cutaneous [lcSSc, n = 20], diffuse cutaneo

Optimum operating conditions of a fuel cell will provide its maximum efficiency and the operating cost will be minimized. Thus, operation optimization of the fuel cell is essential. Neural networks can simulate systems without using simplifying assumptions. Therefore, the neural network can be used to simulate complex systems. This paper investigates the effects of important parameters, i.e., temp