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Impact of Human Papillomavirus (HPV)-6/11/16/18 Vaccine on All HPV-Associated Genital Diseases in Young Women.

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

Objectively measured daily physical activity related to cardiac size in young children.

Training studies in children have suggested that endurance training can give enlargement of cardiac dimensions. This relationship has not been studied on a population-based level in young children with objective methods. A cross-sectional study was made of 248 children (140 boys and 108 girls), aged 8-11 years, from a population-based cohort. Left ventricular end-diastolic diameter (LVDD) and left

A Profession in Change : A Development Ecology Perspective

Popular Abstract in French Un Etat-providence se compose d’une variété d’organisations clientes dans lequel, parmi d’autres professions, les universitaires et les travailleurs sociaux sont actifs. Le travail social comme une profession s’est développé dans un contexte de bien-être où les changements à différents niveaux de l’individu, de l’organisation et la société pose de nouveaux défis pour la A welfare state consists of a variety of client organisations withinwhich, among other professions, academics and social workers areactive. Social work as a profession has developed in a welfare contextwhere changes at the different levels of the individual, organisationand society constantly pose new challenges to the profession.When a society undergoes a total transformation, this also affectshi

Development of the 3-SET 4P questionnaire for evaluating former ICU patients' physical and psychosocial problems over time: A pilot study.

BACKGROUND: Current studies reveal a lack of consensus for the evaluation of physical and psychosocial problems after ICU stay and their changes over time. OBJECTIVES: The aim was to develop and evaluate the validity and reliability of a questionnaire for assessing physical and psychosocial problems over time for patients following ICU recovery. PATIENTS: Thirty-nine patients completed the questio

The Effects of Financial Risks on Inventory Policy

The effect of financial risks on (R, Q) inventory policies is analyzed in a real options framework. Simple adjustments of the usual formulas for R and Q are suggested and tested. Stochastic demand and purchase costs are considered, both with known systematic (business-cycle-related) risk. The systematic risk of stochastic demand has typically a negligible effect on the optimal values of R and Q, a

Dual mechanisms of action of the RNA-binding protein human antigen R explains its regulatory effect on melanoma cell migration.

Overexpression of wingless-type MMTV integration site family 5A (WNT5A) plays a significant role in melanoma cancer progression; however, the mechanism(s) involved remains unknown. In breast cancer, the human antigen R (HuR) has been implicated in the regulation of WNT5A expression. Here, we demonstrate that endogenous expression of WNT5A correlates with levels of active HuR in HTB63 and WM852 mel

Cost of Illness from the Public Payers' Perspective in Patients with Ankylosing Spondylitis in Rheumatological Care.

OBJECTIVE: To estimate the incremental costs to public payers for patients with ankylosing spondylitis (AS) of working age compared with reference subjects from the general population. METHODS: We investigated total costs for 3 years (2005-2007) in 116 outpatients under 66 years of age with AS attending rheumatological care in Malmö, Sweden. Mean (SD) age was 46 (11) years and mean (SD) disease du

Influence of naloxone infusion on analgesia and respiratory depression following epidural morphine.

The influence of two different concentrations of iv naloxone infusion on the analgesia and adverse effects of epidural morphine were compared in a double-blind, placebo-controlled study. Forty-five patients undergoing gallbladder surgery were provided postoperative analgesia by 4 mg epidural morphine; they then received an iv infusion over a 12-h period consisting of either 5 micrograms X kg-1 X h

Fibrillatory rate response to candesartan in persistent atrial fibrillation.

Introduction Angiotensin-receptor blockers may exert favourable anti-arrhythmic effects in atrial fibrillation (AF), but their mechanisms are not fully understood. In this study, we tested the hypotheses that (i) candesartan reduces atrial fibrillatory rate and (ii) fibrillatory rate and its response to candesartan are related with the outcome of cardioversion. For this purpose, a post hoc subanal