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Analysis of ball carrier head motion during a rugby union tackle without direct head contact: A case study : A case study

Rugby union players can be involved in many tackles per game. However, little is known of the regular head loading environment associated with tackling in rugby union. In particular, the magnitude and influencing factors for head kinematics during the tackle are poorly understood. Accordingly, the goal of this study was to measure head motion of a visually unaware ball carrier during a real game t

The Macrophage-Specific Role of Protein Tyrosine Phosphatase Non- receptor 23 in Intestinal Inflammation

Behandling av kroniska tarmsjukdomar Är PTPN23 lösningen vi har väntat på? Alla har vi sannolikt någon gång lidit av magproblem i form av smärta eller diarré. Att drabbas av kroniska tarmsjukdomar där besvären utgör en vardag är ett globalt problem, och trots att sjukdomarna är vanliga finns idag inget botemedel. I den här studien har vi undersökt om en eliminering av molekylen PTPN23 från makrofThe gastrointestinal tract encounters foreign antigens, commensal bacteria and nutrients on a daily basis. Under steady state conditions, a regulatory immune system maintains gut homeostasis. However, disruption of the balance between regulatory components and defeating invading pathogens leads to overshooting inflammatory reactions that can culminate in chronic and relapsing intestinal inflammati

Towards computational modelling of active response in cyclist falls from in-the-wild footage

The self-protective effects of active response in unplanned falls is a well-established, yet under-researched area. Our recent study demonstrated how single cyclist falls are prevalent (i.e., cyclist road traffic collisions not involving another road user), and that active response is of particular importance in these cases. This phenomenon has not been considered in previous computational modelli

Streamlined and abundant bacterioplankton thrive in functional cohorts

While fastidious microbes can be abundant and ubiquitous in their natural communities, many fail to grow axenically in laboratories due to auxotrophies or other dependencies. To overcome auxotrophies, these microbes rely on their surrounding cohort. A cohort may consist of kin (ecotypes) or more distantly related organisms (community) with the cooperation being reciprocal or nonreciprocal and expe

Strategic Communication of Trustworthiness in Autonomous Systems, Machine Learning, & AI

Autonomous systems, machine learning, and artificial intelligence are continuously integrated into our everyday lives. Accompanying this trend is a renewed distrust and concern that technological development may outpace creator control with deleterious results for society. The trustworthiness of the systems and the organisations that operate them is gaining greater attention in public discourse, m

Alignment of Strategic Communication for International Organisations with Diverse Multiple Country Branches

The purpose of this paper is to analyse the phenomenon of country branch’s communication alignment between the corporate and country-specifics, based on the example of the German development organisation GIZ and its country branch GIZ Pakistan. This includes how the communication strategy and concepts are aligned and how the alignment is negotiated and decided. The analysis is guided by the interp

Creation of identity value in video advertising: Performing identity myths of stigmatized groups of society

Brands have changed their approach to advertising, instead of offering products, nowadays they offer ways of living and seeing the world. To do so, they own a symbolic language which is embodied in advertising discourse. Brands aim to create more profound relationships with consumers and to concretise it, they have a variety of strategies at hand. The most common is through brand personification,

Discovery of a novel methanogen prevalent in thawing permafrost

Thawing permafrost promotes microbial degradation of cryo-sequestered and new carbon leading to the biogenic production of methane, creating a positive feedback to climate change. Here we determine microbial community composition along a permafrost thaw gradient in northern Sweden. Partially thawed sites were frequently dominated by a single archaeal phylotype, Candidatus 'Methanoflorens stordalen

Methane dynamics regulated by microbial community response to permafrost thaw

Permafrost contains about 50% of the global soil carbon. It is thought that the thawing of permafrost can lead to a loss of soil carbon in the form of methane and carbon dioxide emissions. The magnitude of the resulting positive climate feedback of such greenhouse gas emissions is still unknown and may to a large extent depend on the poorly understood role of microbial community composition in reg

Characterization of the Corynebacterium pseudotuberculosis enzyme CP40

Amazing scissors or revolutionizing treatments? Autoimmune diseases, cancer and allergies are something that is on the rise in the Western world and can cause major problems in everyday life, in the worst case even death. In addition to that, we have a growing problem with antibiotic-resistant bacteria and increased complications for both healthy people, and especially for those who already have

Role of TSLP signaling in airway structural cells during rhinovirus infection in regard to asthma

Asthma is a chronic inflammatory condition caused by a complex interaction between genetic and environmental factors. The immune response to various environmental triggers is thought to play a major role in driving the chronic inflammation in asthma. The most common trigger related to asthma exacerbations are infections with rhinovirus (RV). RV triggered bronchial epithelial cells (BECs) have show

A Psychometric Evaluation of the Expanded Version of the Inventory of Depression and Anxiety Symptoms (IDAS-II) in Children and Adolescents

The expanded version of the Inventory of Depression and Anxiety Symptoms (IDAS-II) is a self-report measure of 18 empirically derived internalizing symptom dimensions. The measure has shown good psychometric properties in adults but has never been evaluated in children and adolescents. A Swedish version of the IDAS-II was administered to 633 children and adolescents (Mage =16.6 [SD = 2.0]) and 203

Experience without self : Phenomenology and neural correlates of selflessness

Det här avhandlingsprojektet handlar om självmedvetande och hur det förhåller sig till medvetande i stort. Mer specifikt handlar det om jagupplevelse, känslan av att vara ett jag, och om denna känsla med nödvändighet finns med i alla våra upplevelser eller inte. Vad betyder det då att ha en känsla av att vara ett jag? Det kan betyda flera saker, exempelvis känslan av att vara samma person över tidThe present dissertation project concerns the relationship between self and consciousness. Specifically, it concerns the phenomenal sense of self and if this is a necessary component of all experience or not. What is it to have a sense of self? This can refer to several things, such as the sense of being a continuous person through time, the sense of having a body, the sense of being in control of

Postoperative three-dimensional endoanal ultrasound findings and relation to anal fistula plug failure

ObjectivesTo explore the utilization of three-dimensional (3D) endoanal ultrasound (EAUS) for the follow-up of the anal fistula plug (AFP), describe morphological findings in postoperative 3D EAUS, and evaluate if postoperative 3D EAUS combined with clinical symptoms can predict AFP failure.Materials and methodsA retrospective analysis of 3D EAUS examinations performed during a single-centre study

Concordance between the Stockholm Workshop Scale and the International Consensus Criteria for grading the severity of neurosensory manifestations in hand-arm vibration syndrome in a Swedish clinical setting

OBJECTIVES: Occupational exposure to vibration using hand-held tools may cause hand-arm vibration syndrome (HAVS). Correct diagnosis and grading of severity are crucial in protecting the individual's health and for workers' compensation claims. The International Consensus Criteria (ICC) has been suggested to replace the widely used Stockholm Workshop Scale (SWS). The aims were to, in a clinical se

Spherical White with Diamond

A stereo work, part of the site-specific public work, 'Spherical White with Diamond' commissioned by NATUR North Atlantic Tales/Curated Place in collaboration with National Trust Formby. Voice: Jez Dolan.

ABCC3 is a novel target for the treatment of pancreatic cancer

Pancreatic Ductal Adenocarcinoma (PDAC) is a very aggressive disease, lacking effective therapeutic approaches and leaving PDAC patients with a poor prognosis. The life expectancy of PDAC patients has not experienced a significant change in the last few decades with a five-year survival rate of only 8%. To address this unmet need, novel pharmacological targets must be identified for clinical inter

The role of tradesmen and craftsmen in Mersin urban economics : an analysis of institutional, sectoral-based and location of activity

Urbanization is not only a concentration of humans in city areas but also, the consumption and production activities that are comprised in urban space. In this sense, goods and services are developed through the urban economic actors, through labor, economic diversity, and prosperity. This article reviews the relationship between urban economics and tradesmen & craftsmen (TC). The focus is on

Digital Disruption and Rethinking the ‘Script’ of Peace Mediation

This article focuses on the quest for digitalisation in peace mediation and to the extent to which digital disruption is reshaping its practices. While digitalisation in the wider field of diplomacy has seen dramatic changes in its practices, peace mediation is a ‘latecomer’. The article explores the constitutive effects on specific norms and practices of peace mediation and identifies opportuniti