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Fibrinogen can support host antimicrobial containment/clearance mechanisms, yet selected pathogens appear to benefit from host procoagulants to drive bacterial virulence. Here, we explored the hypothesis that host fibrin(ogen), on balance, supports Staphylococcus aureus infection in the context of septicemia. Survival studies following intravenous infection in control and fibrinogen-deficient mice

During adult neurogenesis, newly formed olfactory bulb (OB) interneurons migrate radially to integrate into specific layers of the OB Despite the importance of this process, the intracellular mechanisms that regulate radial migration remain poorly understood. Here, we find that microRNA (miRNA) let-7 regulates radial migration by modulating autophagy in new-born neurons. Using Argonaute2 immunopre

Hur kan juridiken användas för att motverka strukturell diskriminering. Det är en av de många frågor som ställs i "Att förstå lagstiftning om diskrimineirng och mänskliga rättigheter". Syftet med boken är att ge kunskap och verktyg för rörelse ock aktivitet. I sju kapitel tas frågor upp genom exempel som handlar om bland annat anställning, rätten till bostad, löner och åldersdiskrimineirng. Gränse

Den svenska arbetsdomstolen har visat en stor motvilja mot att använda diskrimineringslagen och dess föregångare mot arbetsgivare som följer den svenska arbetsmarknadsmodellen. Detta belyses med rättsfallen AD 2005 nr 69 och 2013 nr 64. I båda dessa rättsfall hade fackföreningen valt att gå domstolsvägen utan att först ha använt alla verktyg som deras kollektivavtal gav. Något som ska vara tillåte

Aims: Pain and anxiety are commonly reported among those undergoing orthopaedic surgery. Improvement in anxiety and pain control might be achieved by supplementing standard care with psychological interventions. However, the effectiveness of adjunctive psychosocial interventions in anxiety and pain control have not been addressed sufficiently by previous systematic reviews in orthopaedic surgeries

Measuring hypnotizability is an integral part of hypnosis research and is also relevant for predicting effectiveness of hypnosis-based therapies. The Elkins Hypnotizability Scale (EHS) was designed to meet the needs of modern hypnosis research and clinical practice. Reliability, validity, and normative data were explored by subjecting 230 participants to the EHS and Stanford Hypnotic Susceptibilit

Health related quality of life (HRQoL) is negatively impacted in patients suffering from Parkinson's disease (PD). For the specific components that comprise HRQoL, the relationship between clinical variables, such as disease duration, is not fully characterized. In this cross-sectional study (n = 302), self-reported HRQoL on the Parkinson's Disease Questionnaire (PDQ-39) was evaluated as a global

Objective To explore the factor structure of the Maternal–Fetal Attachment Scale (MFAS) and investigate its psychosocial and demographic correlates in a Hungarian sample. Design Cross-sectional survey. Setting Sonography clinic in a metropolitan area. Participants One hundred fourteen women over the age of 18 years in the second or third trimesters of pregnancy. Methods Participants completed the

Clinical evidence for the effectiveness of hypnosis in the treatment of acute procedural pain was critically evaluated based on reports from randomized controlled clinical trials (RCTs). Results from the 29 RCTs meeting inclusion criteria suggest that hypnosis decreases pain compared to standard care and attention control groups and that it is at least as effective as comparable adjunct psychologi

Exploring autonomic nervous system (ANS) changes during hypnosis is critical for understanding the nature and extent of the hypnotic phenomenon and for identifying the mechanisms underlying the effects of hypnosis in different medical conditions. To assess ANS changes during hypnosis, electrodermal activity and pulse rate variability (PRV) were measured in 121 young adults. Participants either rec

In this pilot study, the authors introduce a new system to assess hypnosis style. The Feature-Based Coding System (FBCS) comprises 24 standard individual hypnosis sessions, which were videotaped and coded according to both a previous and the new coding system. In addition, both subjects and hypnotists filled the Archaic Involvement Measure (AIM), the Phenomenology of Consciousness Inventory (PCI),

Since the discovery of the mirror neuron system, it has been proposed that the automatic tendency to copy observed actions exists in humans and that this mechanism might be responsible for a range of social behavior. A strong argument for automatic behavior can be made when actions are executed against motivation to do otherwise. Strategic games in which imitation is disadvantageous serve as ideal

This paper argues that studying why and when people call certain actions stupid should be the interest of psychological investigations not just because it is a frequent everyday behavior, but also because it is a robust behavioral reflection of the rationalistic expectations to which people adjust their own behavior and expect others to. The relationship of intelligence and intelligent behavior ha

Objective: This paper describes a randomized controlled single blind study testing the effects of a patient education intervention combined with positive therapeutic suggestions on anxiety for cataract surgery patients. Methods: 84 patients participated in the study. Physiological and behavioral indicators of anxiety were compared between a regularly treated control and an intervention group recei

Changes in oxytocin and cortisol levels were tested in healthy volunteers during hypnotic interactions in standardized laboratory sessions. Preto posthypnosis changes of oxytocin and cortisol were related to the hypnotic susceptibility of subjects and the relational experiences reposted by subjects and hypnotists on several paper-and-pencil tests. Results show that the changes in oxytocin are not

BACKGROUND: Suggestive interventions such as hypnosis and therapeutic suggestions are frequently used to alleviate surgical side effects; however, the effectiveness of therapeutic suggestion intervention has not yet been systematically evaluated. In the present study, we tested the hypotheses that (1) suggestive interventions are useful for reducing postoperative side effects; (2) therapeutic sugg

Introduction: There is an ever reoccurring question in medical practice: Does the positive attitude and communication of the medical staff make any diff erence Aim: Our aim is to present a comprehensive overview of the medically relevant eff ects of positive suggestions by reviewing the recent literature. Methods: We will review the studies measuring the eff ects of suggestive communication of the