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Background: In Sierra Leone persons with disabilities are at higher risk of living in poverty and have poor access to a fragile healthcare and rehabilitation services. The aim was to explore stakeholders’ perceptions of access to health and rehabilitation services for persons with disabilities in Sierra Leone. Methods: Seven focus group discussions, including stakeholders working within the field

EBLM J0113+31 is a moderately bright (V = 10.1), metal-poor ([Fe/H] ≈-0.3) G0V star with a much fainter M dwarf companion on a wide, eccentric orbit (= 14.3 d). We have used near-infrared spectroscopy obtained with the SPIRou spectrograph to measure the semi-amplitude of the M dwarf's spectroscopic orbit, and high-precision photometry of the eclipse and transit from the CHEOPS and TESS space missi

The present article describes a study of the effects of alpha-amylase (α-amylase) on the human neuroblastoma (NB) cell lines SH-SY5Y, IMR-32, and LA-N-1. NB is the most common malignancy diagnosed in infants younger than 12 months. Some clinical observations revealed an inverse association between the risk of NB development and breastfeeding. α-Amylase which is present in breast milk was shown to

Purpose: The purpose of this study is to conduct a systematic literature review that illuminates the current state of knowledge regarding the specific approaches by which multinational corporations (MNCs) implement corporate social responsibility (CSR) on the subsidiary level in developing countries. Design/methodology/approach: Even though substantial scholarly work has been made to outline MNCs'

Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard approaches of PRS construction. Here, we implemented computationally efficient, penalized, logistic regression models (lasso, elastic net, stepwise) to individ

Discrepancies in views of the Self are suggested to be negatively related to well-being (Higgins, 1987). In the present study, we used a novel concept, Personality Estimation Discrepancy (PED), to test this classic idea. PED is defined as the computed difference between how one view oneself (Self-Perceived Personality) and a standard Big Five test (IPIP-NEO-30). In a pre-registered (osf.io) UK onl

We consider a numerical approximation of a linear quadratic control problem constrained by the stochastic heat equation with nonhomogeneous Neumann boundary conditions. This involves a combination of distributed and boundary control, as well as both distributed and boundary noise. We apply the finite element method for the spatial discretization and the linear implicit Euler method for the tempora

Ramjet propulsion is commonly preferred to power supersonic and hypersonic vehicles for cruising faster than Mach 3. This is an elegant solution owing to the lean architecture which does not embody any rotating parts. Although the geometry of the engine is simple as compared to turbine based configurations, the flow physics through the engine duct is quite complex and the flow speeds modulate betw

We describe the design and implementation of a new constraint programming solver that can produce an auditable record of what problem was solved and how the solution was reached. As well as a solution, this solver provides an independently verifiable proof log demonstrating that the solution is correct. This proof log uses the VeriPB proof system, which is based upon cutting planes reasoning with

Social norms guide humans’ everyday behavior, and previous research has shown that social norms consistently predict some forms of political participation. Failure to conform to norms may lead to deviation and possible rejection, which humans innately seek to avoid since it threatens their need for belongingness. Following an episode of rejection, individuals are therefore likely to become increas

In particle collider experiments, elementary particle interactions with large momentum transfer produce quarks and gluons (known as partons) whose evolution is governed by the strong force, as described by the theory of quantum chromodynamics (QCD)1. These partons subsequently emit further partons in a process that can be described as a parton shower2, which culminates in the formation of detectab

Background: Pancreatic ductal adenocarcinoma is a highly fatal malignancy. The aim was to identify preoperative factors for early mortality in up-front resectable patients following pancreatoduodenectomy (PD) and develop an early mortality risk score. Methods: Patients registered in the Swedish National Registry for Pancreatic and Periampullary Cancer were included. Relevant preoperative factors (

The historical subclassification of diabetes into predominantly types 1 and 2 is well appreciated to inadequately capture the heterogeneity seen in patient presentations, disease course, response to therapy and disease complications. This review summarises proposed data-driven approaches to further refine diabetes subtypes using clinical phenotypes and/or genetic information. We highlight the bene

A new combination, Nephromopsis annae (Oxner) A.Thell & Divakar is proposed and the basionym Cetrariasubalpina Imshaug is preferred over the combination in Nephromopsis.

The COVID-19 pandemic, climate crisis, and a shifting geopolitical landscape present us with strategic, ethical and planetary dilemmas that demand more reflective action on behalf of actors at every level. The identified challenges of the not-so-distant future require a fundamental transformation of how companies do business, and the role of business schools in shaping the business practices of th

Encounters between patients in homecare and nursing students are cultural events where students, in principle, are in unknown territory. This study illuminated how nursing students recount (inter)actions in social relations in Danish homecare settings, illustrated by students with a self-appointed immigrant background. The study consisted of semi-structured interviews with eight nursing students.