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BACKGROUND: Bladder cancers have high total mutation burdens resulting in genomic diversity and intra-and inter-tumor heterogeneity that may impact the diversity of gene expression, biologic aggressiveness, and potentially response to therapy. To compare bladder cancers among patients, an organizational structure is necessary that describes the tumor at the histologic and molecular level. These 'm
Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasound-guided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrosp
Background: Patients in intensive care units (ICUs) are among the most vulnerable, and they require support to start their recovery. The design of the patient area in the ICU can play a prominent role in both the quality of care and patients’ recovery. The lighting environment has the opportunity to restore and strengthen the natural human circadian rhythm and health. Aim: To evaluate patients’ se
Purpose: To evaluate urinary continence (UC) recovery and oncological outcomes in different risk-groups after robot-assisted radical prostatectomy (RALP) and open retropubic radical prostatectomy (RRP). Patients and methods: We analysed 2650 men with prostate cancer from seven open (n = 805) and seven robotic (n = 1845) Swedish centres between 2008 and 2011 in a prospective non-randomised trial, L
Dagens situation med begränsad kapacitet i elnätet kan leda till allvarliga problem. Eftersom ”först-till-kvarn” gäller finns det risk för att internationella företag konkurrerar ut lokala verksamheter.
Background: Infertility is a well-known sequela of cancer treatment. Despite guidelines recommending early discussions about risk of fertility impairment and fertility preservation options, not all patients of reproductive age receive such information. Aims: This study aimed to investigate young adult cancer patients’ receipt of fertility-related information and use of fertility preservation, and
The benefit of surgery in high-grade gastroenteropancreatic neuroendocrine neoplasms (GEP NEN) and mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) is uncertain. The present study aimed to investigate outcomes after tumour surgery in patients with high-grade (Ki-67 > 20%) GEP NEN or MiNEN stage I-III or stage IV. We analysed data from patients treated in the period 2007-2015 at eight Nord
Crocodilians are the closest living relatives of birds and share many ecological challenges with mammalian apex predators. They evolved perception pathways that share similarities with both taxa, birds and mammals. Due to their position in the tree of life, crocodilians therefore represent a promising intermediate model for comparative research. In this review, the different modalities of percepti
With global efforts in reducing energy consumption, house manufacturers are seeking use of new materials and design solutions. However, some believe this will increase the risk of mould. One way to assess the mould risk is to use a hygrothermal software for simulating the climate envelopes’ moisture performance. But as with all simulation, the quality of the output can never be better than the qua
987/5000En omfattande ram för en hållbar renoveringsprocess med en helhetssyn på renovering har utvecklats med beaktande av områdena: teknik, miljö, ekonomi, sociala värden och arkitektur och kulturhistorisk miljö. Ramverket beskriver aktiviteter som ska genomföras i olika steg i processen, samt kartlägger vem som kommer att ansvara för och utföra dessa aktiviteter. Ramverket hänvisar till tillgänA comprehensive framework for a sustainable renovation process with a holistic approach to renovation has been developed, taking into consideration the areas: technology, environment, economy, social values, and architecture and cultural historical environment. The framework describes activities that should be carried out at different stages of the process, as well as charting who will be responsi
In Europe, all new houses built require an energy declaration showing the expected energy consumption during use. However, there is often a discrepancy between the calculated and the actual energy consumption. Some claim that in general the difference is on the positive side for wooden buildings, with real energy consumption being lower than predicted. This could be an effect of thorough and long-
Inom byggsektorn måste byggnader vara mer energieffektiva än någonsin tidigare. Tuffare byggregler kräver allt mer exakta energibehovsberäkningar för att säkerställa byggnadens operativa prestanda. Överföringsvärmeöverföringsförluster genom byggnadens kuvert spelar en nyckelroll i byggnadens totala energiprestanda. Att underskatta dessa förluster kan leda till att energikraven inte uppfylls. För nWithin the construction sector buildings are required to be more energy efficient than ever before. Tougher building regulations require ever more accurate energy demand calculations to ensure a building’s operational performance. Transmission heat transfer losses through a building’s envelope play a key role in the overall energy performance of the building. Underestimating these losses may lead
This article explores municipal variation in the implementation of a Danish educational reform. The aim of the reform was to increase the assimilation of immigrants, and removing mother-tongue training for first- and second-generation immigrants was believed to increase their proficiency in Danish. This article uses a difference-in-differences method to explore the effect of this removal on childr
The major softwood hemicellulose is galactoglucomannan (GGM), an abundant polysaccharide which constitutes up to 25% of the dry weight of wood, much of which is discarded in current refinery practices. Among the enzymes responsible for the degradation of this hemicellulose are the β-mannanases. Apart from their natural hydrolytic action, some β-mannanases have the ability to catalyse the synthesis
Pickering emulsions are emulsions stabilized by solid particles. Particles with optimal dual wettability toward both of the oil and water phases, can be adsorbed onto the interface, thereby providing the stability of the emulsions. Starch granules have attracted attention due to their positive characteristics, such as being widely available, inexpensive, biodegradable, and non-allergenic. Due to a
I denna studie genomförs en uppdaterad analys av potentialen för en ökad tillförsel av biomassa från skog, jordbruk och akvatiska system i Sverige till 2030 respektive 2050. Studien tar sin utgångspunkt i en tidigare potentialstudie från 2016 men där potentialen för respektive biomassakategori justerats efter de omvärldsförändringar som skett och ny kunskap som tagits fram under de senaste fem åreThis study include an updated analysis of the potential increase in the supply of biomass from forest, agriculture and aquaculture in Sweden until 2030 and 2050, respectively. The study is based on a previous assessment from 2016 but where the potential of different categories of biomass feedstocks is revised according to new knowledge and changed conditions during the last five years. The estimat
