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Effect of encapsulated protein on the dynamics of lipid sponge phase: a neutron spin echo and molecular dynamics simulation study

Lipid membranes are highly mobile systems with hierarchical, time and length scale dependent, collective motions including thickness fluctuations, undulations, and topological membrane changes, which play an important role in membrane interactions. In this work we have characterised the effect of encapsulating two industrially important enzymes, β-galactosidase and aspartic protease, in lipid spon

Health care professionals' experiences of screening immigrant mothers for postpartum depression-a qualitative systematic review

INTRODUCTION: Postpartum depression is considered a major public health problem, which immigrant mothers are at particular risk of being affected by, but it can also have long-lasting traumatic effects on the child's health and development. The Edinburgh Postnatal Depression Scale is the world's most commonly employed screening instrument for postpartum depression, used in connection with a clinic

Sex-limited chromosomes and non-reproductive traits

Sex chromosomes are typically viewed as having originated from a pair of autosomes, and differentiated as the sex-limited chromosome (e.g. Y) has degenerated by losing most genes through cessation of recombination. While often thought that degenerated sex-limited chromosomes primarily affect traits involved in sex determination and sex cell production, accumulating evidence suggests they also infl

Partnering for Transformation - exploring the concept of Transformative Academic Institutions

Academic institutions are frequently called on to evidence the impact they have on their regional ecosystems whilst at the same time respond to the expectations that they produce globally significant research. This often results in tensions because of the different drivers and rewards of these dual ambitions.This exploratory research project describes how international academic partners across fiv

Evidencing the benefits of cluster policies: towards a generalised framework of effects

Regions around the world employ cluster-based policies as part of their industrial, innovation and development policy mixes. They have become a key tool in smart specialisation strategies and are increasingly used to address societal challenges. Given their popularity and longevity, there is significant demand to better measure and understand the impacts of cluster policies. Yet the diversity of cRegions around the world employ cluster-based policies as part of their industrial, innovation and development policy mixes. They have become a key tool in smart specialisation strategies and are increasingly used to address societal challenges. Given their popularity and longevity, there is significant demand to better measure and understand the impacts of cluster policies. Yet the diversity of c

Prediction of soil cation exchange capacity using enhanced machine learning approaches in the southern region of the Caspian Sea

Cation exchange capacity (CEC) has a key role in soil studies such as agriculture, energy balance, characteristics of the soil for food, maintaining water in the soil as well as soil pollution management. Its measurement is difficult and time-consuming. So, its prediction using artificial intelligent (AI) models with soil readily available properties can be the proper solution. In this study, the

Identification of a Catalytic Nucleophile-Activating Network in the endo - α -N- Acetylgalactosaminidase of Family GH101

Bifidobacterium longum endo-α-N-acetylgalactosaminidase (GH101), EngBF, is highly specific toward the mucin Core 1 glycan, Galβ1-3GalNAc. Apart from the side chains involved in the retaining mechanism of EngBF, Asp-682 is important for the activity. In the crystal structures of both EngBF and EngSP (from Streptococcus pneumoniae), we identified a conserved water molecule in proximity to Asp-682 an

Quantitative evaluation of the tibiofemoral joint cartilage by T2 mapping in patients with acute anterior cruciate ligament injury vs contralateral knees : results from the subacute phase using data from the NACOX study cohort

Objective: Immediate cartilage structural alterations in the acute phase after an anterior cruciate ligament (ACL) rupture may be a precursor to posttraumatic osteoarthritis (PTOA) development. Our aim was to describe changes in cartilage matrix in the subacute phase of the acutely ACL-injured knee compared to the contralateral uninjured knee. Design: Participants (n = 118) aged 15–40 years with a

Malaria and Helminthic Co-Infection during Pregnancy in Sub-Saharan Africa : A Systematic Review and Meta-Analysis

Malaria and helminthic co-infection during pregnancy causes fetomaternal haemorrhage and foetal growth retardation. This study determined the pooled burden of pregnancy malaria and helminthic co-infection in sub-Saharan Africa. CINAHL, EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were used to retrieve data from the literature, without restricting language and publication ye

Participation in exercise-based cardiac rehabilitation is related to reduced total mortality in both men and women : Results from the SWEDEHEART registry

Aims: Participation in exercise-based cardiac rehabilitation (exCR) increases aerobic capacity and improves outcomes in patients following myocardial infarction (MI) and is therefore universally recommended. While meta-Analyses consistently report that participation in exCR reduces cardiovascular mortality, there are conflicting results regarding effects on total mortality. Presently, many eligibl

Small angle X-ray scattering from MCM-41 and its synthesis gels : optimisation of the synthesis parameters

We have found optimised conditions for alkaline synthesis of the large pore molecular sieve, MCM-41, by determining small angle X-ray scattering and adsorption isotherms from materials at various stages of the preparation. The presence of highly curved surfaces, sealed structures, and quasicrystalline hexagonal products coexisting with true MCM-41 are all detected by transmission electron microsco