Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to retreatment present continuing areas for research. The disease and its effective treatment are associa

An important issue in clinical neural grafting is whether a second instriatial allograft can survive well in a patient who has received an allograft before. In this study, the survival, immunogenicity and function of intrastriatal grafts of allogeneic or syngeneic embryonic dopamine-rich tissue in rats which had previously received either an intrastriatal allo- or syn-graft or sham injections were

Fetal mesencephalic mouse tissue, rich in dopamine neurons, was xenografted as a dissociated cell suspension into the striatum of rats with unilateral 6-hydroxydopamine induced lesions of the mesostriatal pathway. The rats were either assigned to a 10-day, 21-day or 42-day Cyclosporin A (CyA) immunosuppression scheme, or given no immunosuppression. The functional effects of the grafts were followe

Acute lymphoblastic leukemia (ALL) is classified as B-lineage ALL (B-ALL) and T-lineage ALL (T-ALL). The incidence of ALL is almost three times higher in white than black children. Among adults, ALL is more frequent in younger patients, with a median age of less than 30 years. The morphology-immunology-cytogenetics (MIC) subgroups are associated with nonrandom karyotypic abnormalities in a manner

Valentinus av Alexandria var en teolog och predikant vars verksamhet under det andra århundradet fick stort genomslag. Valentinianernas evangelium – den världsbild och teologi som kan knytas till Valentinus och hans efterföljare – var intimt förknippat med fenomenet gnosticism. Men vad är egentligen gnosticism och hur hänger den ihop med kristendom? Den här boken är en introduktion till antik gnos

The language of newspapers in the public sphere has a crucial impact on how the public perceives and participates in society. It can serve to encourage or counteract active and informed citizens; in fact, it is a crucial element in democratisation processes. The purposes of the present study are to elucidate what means of persuasion are used to support theses on politics in newspaper discours

The TIMESAT software package has been developed to enable monitoring of dynamic land surface processes using remotely sensed data. The monitoring capability is based on processing of time-series for each image pixel using either of three smoothing methods included in TIMESAT: asymmetric Gaussian fits, doublelogistic fits, and Savitzky-Golay filtering. The methods have different properties and are

To demonstrate and support sustainability of large-scale infrastructure projects, life cycle assessment (LCA) has become a common tool used in the evaluation of environmental impact. However, LCA includes a number of phases, which are all associated with uncertainties. Decisions made without regard to these uncertainties may be suboptimal and/or misleading. The current paper discusses some importa