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Popular Abstract Våra celler presenterar med hjälp av protein på sina ytor korta peptidfragment härrörande från intracellulära proteiner med syfte att signalera till utsidan om hur cellen mår. Är cellen sjuk ändras peptidrepertoaren, dvs de peptidfragment som uppvisas, vilket direkt upptäcks av kroppens cirkulerande T-celler som då förstör cellen. En viktig del i processen är att välja vilka små fTapasin is a membrane protein, which plays a crucial role involved antigen presentation for certain MHC alleles in antigen presentation. Tapasin acts as a link between Transported Associated with antigen Processing (TAP) and MHC class l by. It acts as quality control in choosing high affinity peptides to be presented. Refolding conditions for the N-­terminal region of tapasin have here been invest

Analysing eye movements recorded with mobile eye-tracking devices is difficult since the eye-tracking signals are severely affected by simultaneous head and body movements. The automatic analysis methods developed for static eye-tracking systems do not take this into account and are therefore not suitable for application to data which also contains head and body movements. As a result, data record

IT ses ofta som en del av lösningen för att uppnå ett hållbart samhälle genom till exempel minskat resande, optimering av industri- och jordbruksprocesser, intelligenta elmätare och smarta hem. Något man sällan reflekterar över är att ITbranschen själv också bidrar till elanvändningen. Ett nytt fenomen inom IT-världen är molnet som ger möjlighet till som det verkar outtömliga resurser i form av laInformation and communication technology (ICT) is often seen as part of the solution for a sustainable society, for example through reduced travel, optimization of industrial and agricultural processes, smart meters and smart homes. However, something usually left unconsidered is the electricity consumption of ICT itself. A new phenomenon of the ICT industry is the Cloud that enables seemingly ine

The purpose of this paper is to perform a new study to add support for one of the three explanations of the Great Moderation; the explanation based on a change in monetary policy. The study focuses on the U.S., the U.K., and Australia during the period 1970 Q1-2013 Q3. The study is performed by exploring whether the Moderation (persistent decline in output volatility) was caused by volatility beha

In my thesis I have been exploring the opportunities and possibilities in developing new concepts for mobile communication device for younger kids. The project has been commissioned through Designit with the purpose to further explore and investigate how to tap into the market of mobile communication for young users. The project at hand is interesting because we are looking at a situation where t

This study implements a quantitative approach. For calculating excess cash we use Opler et al. (1999) approach. For bid premia model we use Alexandridis et al. (2013) approach. Testing our hypothesis we use regression analysis. We also include a survivorship bias approach. Public acquisitions by firms in the S&P 500 index; we also include dropped firms to bypass survivorship bias. Henceforth w

Radon (222Rn) är en naturligt förekommande radioaktiv gas som i höga doser visat sig vara dödlig. Det handlar främst om de solida radondöttrarna som fäster på aerosolpartiklar vilka vi andas in och kan på så vis deponeras i näsa eller svalg, medan fria joner lägger sig på lungornas bronker och avger joniserande strålning. Epidemiologiska studier har visat att rökare löper högre risk än icke rökareRadon (222Rn) is a naturally occurring radioactive gas that can be fatal in high doses. It is primarily the solid radon daughters that attach to aerosol particles, which we inhale and can thus be deposited in our nose or throat, while free ions settles on pulmonary bronchi and emits ionizing radiation. Epidemiological studies have shown that smokers are at higher risk than non-smokers to contract

The paper looks at books that have been adapted from games to see how a relationship between these two medias have changed how the book are portrayed on their cover. To investigate how the covers have been portrayed it looks at several books that have been adapted from a game. The covers are then analyzed based on, how much they limit themselves to their targeted audience, how strong position they

This study examines the representation of everyday lives of men and women in a popular Swedish magazine, Husmodern, in the 1950s. The ”small history” of the 1950s is a relatively forgotten part of modern history and the era is often reduced to nostalgia in popular culture, but rarely researched through a thorough, theoretical lense. By applying the theory of R.W. Connell about Hegemonic Masculinit

When costumers look for a robot for their factory two things are important. The robot should be as efficient as possible, but still be cheap. In order to make the robot efficient the robot-controller has to know the dynamics of the robot and its limits. Based on these it can then generate a time-optimal plan (trajectory) for each movement. The standard way of generating a time-optimal trajectory w

The purpose of this thesis is to investigate how the latency in mobile networks affect the quality of highly demanding and sensitive applications running on it. Furthermore, this thesis will provide some information to what is going on in the field of Cloud Computing and the Internet of Things. It will hopefully spark a discussion about what possibilities will come with the development of the Clou

Population growth, infrastructure and economy puts pressure and demand on the existing power supplies. It puts strains on the current power systems which causes instabilities in the systems. This is an ongoing challenge which needs an immediate solution. The objective of this thesis is voltage stability. This is examined with the help of constructing a small power system using a programming langua

The goal of this study is to find out if participation in an Internet forum can help participants in that Internet forum justify an illegal use of cannabis. Today the most commonly used narcotic in Sweden is Cannabis (CAN 2012). Still, the drug has remained illegal over many years and the Swedish drug policy remains restrictive towards drug use. This paper uses Howard S. Bcker’s three forms of soc

Distriktssköterskan har en nyckelroll i hälsofrämjande arbete med helhetssyn på vårdtagare. Studier har visat att distriktssköterskans roll idag är otydlig och att utbildningen till distriktssköterska är ospecifik. Genom denna otydlighet blir distriktssköterskan utbytbar. Syftet med studien var att beskriva distriktssköterskors erfarenheter av arbete som specialistsjuksköterska på vårdcentral. Stu

In contrast to the Western ideal of secularization, religion has in some cultures maintained its important role in nationalist undertakings. This is the case in Myanmar, a country that is currently in the midst of a state transformation towards democracy after more than fifty years of authoritarian, military rule. This religious nationalism has been taken to a higher level of chauvinism and violen

Syftet med detta examensarbete var att skapa en modell för sambandet mellan absorbans och koncentrationen av sam-eluerurande proteiner. Med jonbyteskromatografi systemet ÄKTA från GE-Healthcare utfördes en separation mellan de tre proteinerna BSA, Lysozyme och IgG. Absorbansen mättes med en UV-mätare vid tre våglängder. Eftersom de nämnda proteinerna inte sameluerar i ett neuturalt pH-värde utfördThe aim of this thesis is to create a model of the correlation between absorbance and concentration of co-eluting proteins. A separation using the chromatograph system ÄKTA from GE-Health care of BSA,Lysozyme and IgG was performed. Absorbance was measured at three different wave lengths. Since the mentioned proteins do not co-elute in a neutral pH the experiments were performed at a high pH-level

Hybrid 56 (H56) is a new vaccine candidate against pulmonary tuberculosis (TB) developed by Staten Serum Institut (SSI) and currently being tested in clinical trial phase IIa. The vaccine consists of three mycobacterial proteins ESAT-6, Ag85B, and Rv2660c that are fused together in a poly-protein. When formulated in a cationic adjuvant (CAF01), Hybrid56 has shown consistent protective efficacy in

I dagens barnhälsovård möter BVC-sjuksköterskan allt fler familjer med samkönade föräldrar. Forskningen antyder att samkönade föräldrar generellt får ett övervägande bra bemötande inom hälso- och sjukvården. Dock tycks forskning kring bemötandet av dessa individer inom barnhälsovården i dag vara begränsad. Syftet med studien var att belysa hur samkönade föräldrar upplever bemötandet från BVC-sju

As hybrid vehicles are growing more popular, new challenges for manufacturers arise to achieve good NVH. This master thesis analyzes an electric motor installation at the rear axle on the Volvo V60 Plug-in Hybrid with the goal to lower the noise level in the vehicle compartment. Measurements are combined with CAE-analyses to understand the problem areas and the behavior of the existing installatio