AD730® is a new type of nickel-based superalloy, developed by Aubert & Duval, with high temperature properties exceeding conventional superalloys such as Alloy 718. This paper presents the tool life model for this superalloy for the purpose of process optimization and manufacturing cost estimation. The tool life modelling is based on comprehensive machining tests, using the Colding model. The

This chapter deals with ways in which digital technologies can be utilized to work with moving media in hybrid ways. It will resonate with practices of ethnographic film, but it will also attempt to move beyond traditional, representational notions of this practice, very much in line with the ideas of the “new world of ethnographic film and video” that Phillip Vannini outlines in the introduction

The proton has a substructure in terms of parton cascades, which in a high energy collision fills the whole rapidity range between projectile and target. In the Good–Walker formalism the fluctuations in the cascades will give rise to diffractive excitation. Within the Lund Dipole Cascade model, it is in this way possible to reproduce diffractive excitation in pp collisions and DIS. In central pp c

This is the report of the work for project Dagsljuskrav i miljöcertifierade byggnader" of the Swedish Energy Agency, project number: 39682-1. The study was focused on the energy use and daylight conditions in the multi-family building Greenhouse located in Malmö, Sweden. The aim of the study was first to analyze and develop innovative design solutions for multi-family dwellings with good daylighti

This is the report of the work carried out for project "Dagsljusanvändning i byggnader" of the Swedish Energy Agency, project number 41816-1. This research provides background scientific information on the daylight performance of multi family apartment blocks located in Stockholm, and Örebro, Sweden. A sample of 54 buildings that consist of 10 888 individual rooms was evaluated using advanced dayl

What can we learn from embryogenesis to increase our understanding of how regeneration of damaged adult lung tissue could be induced in serious lung diseases such as chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and asthma? The local tissue niche determines events in both embryogenesis and repair of the adult lung. Important constituents of the niche are extrace

The glycosaminoglycan dermatan sulfate (DS) is a well-known activator of heparin cofactor II-dependent inactivation of thrombin. In contrast to heparin, dermatan sulfate has never been prepared recombinantly from material of non-animal origin. Here we report on the enzymatic synthesis of structurally well-defined DS with high anticoagulant activity. Using a microbial K4 polysaccharide and the reco

Non-typeable Haemophilus influenzae (NTHi) is a Gram-negative human commensal commonly residing in the nasopharynx of preschool children. It occasionally causes upper respiratory tract infection such as acute otitis media, but can also spread to the lower respiratory tract causing bronchitis and pneumonia. There is increasing recognition that NTHi has an important role in chronic lower respiratory

myo-Inositol hexaphosphate, the salt of myo-inositol hexaphosphoric acid (IP6), is a common constituent of many plant foods, such as cereals and legumes. IP6 interacts with mineral elements, influencing their bioavailability. Processed foods contain a mixture of different inositol phosphates, i.e., IP6 and its degradation products with five or less phosphate groups (IP5-IP1). The interaction of th

PURPOSE: Disruption of splicing motifs by genetic variants can affect the correct generation of mature mRNA molecules leading to aberrant transcripts. In some cases, variants may alter the physiological transcription profile composed of several transcripts, and an accurate in vitro evaluation is crucial to establish their pathogenicity. In this study, we have characterized a novel PALB2 variant c.