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Plasma neurofilament light in behavioural variant frontotemporal dementia compared to mood and psychotic disorders

Objective: Blood biomarkers of neuronal injury such as neurofilament light (NfL) show promise to improve diagnosis of neurodegenerative disorders and distinguish neurodegenerative from primary psychiatric disorders (PPD). This study investigated the diagnostic utility of plasma NfL to differentiate behavioural variant frontotemporal dementia (bvFTD, a neurodegenerative disorder commonly misdiagnos

Comparing Planning Processes in Smartphone Text Messaging to Traditional Writing

In today’s increasingly digital society, smartphone texting is a common means for written communication. In 2018, over 90% of Swedes reported that they engaged in smartphone text messaging (i.e. texting) on a daily basis (Davidsson, Palm, & Melin Mandre, 2018). The aim of this study is to examine and compare planning processes based on the Hayes (1996) writing model in texting with traditional

Packaging innovation scorecard

Innovation literature shows that the characteristics of a company's innovation processes determine their performance in different areas. In this study, we adopt a general conceptual model from innovation theory and apply it to packaging innovation. This helps identify and describe subprocesses in packaging innovation and how to measure their performance. It also links the packaging innovation proc

Retail returns management strategy : an alignment perspective

This research aims to shed light on the formulation of returns management strategies and to identify key returns management components in developing more effective returns management strategies. Anchored in supply chain orientation and supply chain alignment research, we use a multiple confirmatory case study of six retailers operating in online commerce. Interviews with fifteen managers provided

Lingering challenges in everyday life for adults under age 60 with hip fractures–a qualitative study of the lived experience during the first three years

Purpose: We aimed to illuminate the lived experiences and the path of recovery for adults sustaining a hip fracture before the age of 60. Methods: Participants were purposively sampled from a prospective multicenter cohort study in Sweden and Denmark, and narrative interviews were conducted with 19 individuals 0.7–3.5 years after the fracture. We used a phenomenological hermeneutic method to descr

Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI) : a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study

BACKGROUND: Retrospective studies have shown promising results using artificial intelligence (AI) to improve mammography screening accuracy and reduce screen-reading workload; however, to our knowledge, a randomised trial has not yet been conducted. We aimed to assess the clinical safety of an AI-supported screen-reading protocol compared with standard screen reading by radiologists following mamm

Variation in coparenting quality in relation to child age : Links to coparents' relationship satisfaction and education

Coparenting, denoting shared responsibilities in caring for a child, is a core component of parenthood for most parents. Research has linked quality in the coparenting relationship to several child outcomes as well as parent relationship satisfaction and mental health, yet whether and how these links may differ depending on child age is unclear. Here, we investigated links between coparenting qual

Agreement between rapid antigen detection test and culture for group A streptococcus in patients recently treated for pharyngotonsillitis - a prospective observational study in primary care

Objective: The aim was to compare rapid antigen detection test (RADT) and throat culture for group A streptococci (GAS) among patients recently treated with penicillin V for GAS pharyngotonsillitis. Design and setting: The study was a secondary analysis within a randomized controlled trial comparing 5 versus 10 days of penicillin V for GAS pharyngotonsillitis. Patients were recruited at 17 primary

Fatal infective endocarditis caused by Aerococcus sanguinicola : a case report and literature review

Aerococcus sanguinicola is a bacterium that can cause urinary tract infections and on rare occasions infective endocarditis (IE). The prognosis of IE caused by aerococci is generally favourable despite that the patients are typically old and have multiple comorbidities. Here we report a case of A. sanguinicola native valve aortic IE in a 68-year-old man with an underlying urinary tract condition.

Mapping of referral patterns for undescended testes – Risk factors for referral of children with normal testes

Background: Accurate referral of boys with suspected undescended testes (UDT) is of importance to preserve fertility and reduce risk of future testicular cancer. While late referral is well studied, there is less knowledge about incorrect referrals, hence, referral of boys with normal testes. Objective: To evaluate the proportion of UDT referrals that did not lead to surgery or follow-up, and to a

Time to Blood Culture Positivity: An Independent Predictor of Mortality in Streptococcus Pyogenes Bacteremia

BackgroundStreptococcus pyogenes bacteremia is a severe condition with high mortality. Time to blood culture positivity (TTP) is known to predict the outcome in bacteremia with other pathogens. This study aimed to determine the association between TTP and outcome in S pyogenes bacteremia.MethodsThis retrospective observational cohort study comprised adults with S pyogenes bacteremia, identified thBackgroundStreptococcus pyogenes bacteremia is a severe condition with high mortality. Time to blood culture positivity (TTP) is known to predict the outcome in bacteremia with other pathogens. This study aimed to determine the association between TTP and outcome in S pyogenes bacteremia.MethodsThis retrospective observational cohort study comprised adults with S pyogenes bacteremia, identified th

Time to positivity of blood cultures in bloodstream infections with Streptococcus dysgalactiae and association with outcome

PurposeInvasive infections with Streptococcus dysgalactiae predominantly occur in persons of older age with substantial morbidity and mortality. Time to positivity from blood cultures (TTP) has been shown to be a prognostic indicator in bloodstream infections caused by other beta-haemolytic streptococci. This study aimed to determine any possible association between TTP and outcome in invasive infPurposeInvasive infections with Streptococcus dysgalactiae predominantly occur in persons of older age with substantial morbidity and mortality. Time to positivity from blood cultures (TTP) has been shown to be a prognostic indicator in bloodstream infections caused by other beta-haemolytic streptococci. This study aimed to determine any possible association between TTP and outcome in invasive inf

Fracture Characterization of Wood Adhesive Joints

Failure in wood is commonly considered as a sign of properly chosen adhesive for wood adhesive joints. It is argued that as the adhesive is stronger than the surrounding wood material, no concern has to be given to the adhesive properties in joint design. However, by means of theoretical arguments in combination with experimental experience in the present study, it is stated that local bond line p

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Abstract in French:Cet article contribue à la recherche sur la géopolitique urbaine par une théorisation « extrospective » du pouvoir local sur la scène internationale – c’est-à-dire une orientation du développement socio-économique qui encourage tant la concurrence que la coopération entre les entités métropolitaines au-delà des frontières de l’État-nation. Empiriquement, l’article se concentre sThis article contributes to research on urban geopolitics through an extrospective theorization of local territorial influence on the international stage. Empirically, the article focuses on a comparative study of extrospective development initiatives from Malaga (Spain) and Mazara del Vallo (Sicily) that have recently emerged in response to the effects of the Great Recession. We examine the symbo