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Global real interest rate dynamics from the late 19th century to today

There is a long-standing economic debate to what extent interest rates are determined by domestic versus international forces. Using a time series factor model, we estimate two common global factors for the short-term real interest rate for a panel of 17 advanced economies from 1871 to 2013. Our analysis shows that more than 50% of the variation in national real interest rates can be explained by

Paradigm Found? Immanent Critique to Tackle Interdisciplinarity and Normativity in Science for Sustainable Development

The ambition of this two-part article is to argue for immanent critique as a research strategy in sustainability studies. We do this by picking up and developing two central, cross-cutting themes in sustainability research, namely interdisciplinarity and normativity. It is widely suggested that the problem-driven and solution-focused orientation in sustainability studies necessitates interdiscipli

Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

Back pain is the #1 cause of years lived with disability worldwide, yet surprisingly little is known regarding the biology underlying this symptom. We conducted a genome-wide association study (GWAS) meta-analysis of chronic back pain (CBP). Adults of European ancestry were included from 15 cohorts in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, and from th

Gender differences in early systemic sclerosis patients : a report from the EULAR scleroderma trials and research group (EUSTAR) database

METHODS: A cross-sectional analysis of the prospective EULAR Scleroderma Trial and Research database (EUSTAR) was performed. Patients fulfilling preliminary ACR 1980 classification criteria for SSc, with less than 3 years from the first non-Raynaud's symptom at first entry, were selected. A group of patients with less than 3 years from the first SSc symptom, including Raynaud's phenomenon, was als

Being Nassau : Nassau family histories and Dutch national discourse from 1541 to 1616

William I of Nassau, Prince of Orange, and his sons Maurice and Frederick Henry were seen in their own time as the protectors of the new Dutch nation. As such, they play a significant role in the formation of a Dutch national identity. This essay addresses the question in what measure this sentiment was returned: did the Nassaus feel Dutch? An analysis of dynastic arguments used in the Apology (15

Implementing a salutogenic treatment model in a clinical setting of emergency child and adolescent psychiatry in Sweden

Problem: Emergency care in child and adolescent psychiatry often lacks a coherent treatment model. This study reports on the development and implementation of a salutogenic treatment model at the Child & Adolescent Psychiatric Emergency Unit in Malmö, Sweden. Methods: The development and implementation involved all staff categories and was guided by a recognized authority on salutogenesis. Gen

Operation and performance of the ATLAS Tile Calorimeter in Run 1

The Tile Calorimeter is the hadron calorimeter covering the central region of the ATLAS experiment at the Large Hadron Collider. Approximately 10,000 photomultipliers collect light from scintillating tiles acting as the active material sandwiched between slabs of steel absorber. This paper gives an overview of the calorimeter’s performance during the years 2008–2012 using cosmic-ray muon events an

Heat release and flame spread assessment of insulation in External Thermal Insulation Composite System (ETICS) facades

External Thermal Insulation Composite Systems (ETICS) represent a popular modern facade for reducing energy consumption, particularly in retrofit applications. Insulation - typically in the form of either EPS (expanded polystyrene) or mineral wool - is applied to the exterior of buildings using mortar adhesive, and then coated with a final layer of sand-cement render and glass fibre reinforcement.

The molecular clutch model for mechanotransduction evolves

Many biological processes are influenced by the mechanical rigidity of surrounding tissues. Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.

A multicenter evaluation of the safety and effectiveness of a 0h/1h protocol in the assessment of emergency department chest pain patients.

BackgroundIn emergency department (ED) chest pain patients, the European Society of Cardiology recommends the use of a 0h/1h high-sensitivity cardiac Troponin (hs-cTn) protocol. However, the recommendation is based on observational studies and the effects of the protocol when implemented in routine care is unknown. The aim of this study is to determine the safety and effectiveness of the ESC 0h/1h

Search for new phenomena using the invariant mass distribution of same-flavour opposite-sign dilepton pairs in events with missing transverse momentum in √s=13 Te pp collisions with the ATLAS detector

A search for new phenomena in final states containing an e+e- or μ+μ- pair, jets, and large missing transverse momentum is presented. This analysis makes use of proton–proton collision data with an integrated luminosity of 36.1fb-1, collected during 2015 and 2016 at a centre-of-mass energy s=13TeV with the ATLAS detector at the Large Hadron Collider. The search targets the pair production of super

Differences in ultrasound features of papillations in unilocular-solid adnexal cysts : a retrospective international multicenter study

Objectives: To identify ultrasound features of papillations or of the cyst wall that can discriminate between benign and malignant unilocular-solid cysts with papillations but no other solid components. Methods: From the International Ovarian Tumor Analysis (IOTA) database derived from seven ultrasound centers, we identified patients with an adnexal lesion described at ultrasonography as unilocula

Mapping of quick clay using sounding methods and resistivity in the Gota River valley

For a long time, the predominant method for detection of quick clay in Sweden has been to take undisturbed samples and to perform fall-cone tests on the clay in its undisturbed and remoulded state. In connection with a large stability investigation covering both sides of the Gota River, from the lake Vanern to the city of Gothenburg, the usefulness of CPTu and static pressure sounding for mapping

Catch Me if You Can : Streptococcus pyogenes Complement Evasion Strategies

The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for combatting bacterial infection. Complement permits the efficient labelling of bacteria with opsonins, supports phagocytosis, and facilitates phag

Data quality quantification for time domain IP data acquired at a former waste deposit in Lund

Tests were done measuring resistivity and time domain induced polarisation using standard multi-core cable spreads and a special layout with separate cable spreads for transmitting current and measuring potentials. For both types of cables spreads both normal and reciprocal measurements were done in order to estimate the measurement errors. The tests were done on a former landfill in Lund in Swede

Safavid Cousins on the Verge of Extinction : Dynastic Centralization in Central Asia and the Bahrāmī Collateral Line (1517-1593)

The Bahrāmī Safavids, a relatively unknown collateral branch of the Safavid dynasty, active in Iran from 1517 to 1593, played a crucial role in dynastic developments in Safavid Iran. This essay examines the dynastic developments of the Safavid rulers and their contemporaries to argue that they embarked on a process of dynastic centralization, presenting themselves increasingly as the only holder

Climate Science for Policy? The knowledge politics of the IPCC after Copenhagen

Klimatförändringarna kommer att påverka ekosystem och samhällen över hela världen. Det är ett problem som kräver drastiska och omedelbara förändringar av vårt sätt att leva och av våra samhällsstrukturer, och därmed politiskt engagemang av aldrig tidigare skådat slag. Under de senaste 30 åren, sedan bildandet av Förenta Nationernas ramkonvention om klimatförändringar (Klimatkonventionen; UNFCCC) åThe rise of climate change as an issue of global concern has rested on scientific representation and understanding of the causes and impacts of, and responses to climatic change. The Intergovernmental Panel on Climate Change (IPCC), in particular, has been central to how climate change has become known as a global political problem. This thesis aims to critically examine the production, negotiatio