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Intake of Coffee, Decaffeinated Coffee, or Tea Does Not Affect Risk for Pancreatic Cancer: Results From the European Prospective Investigation into Nutrition and Cancer Study

BACKGROUND & AIMS: Few modifiable risk factors have been implicated in the etiology of pancreatic cancer. There is little evidence for the effects of caffeinated coffee, decaffeinated coffee, or tea intake on risk of pancreatic cancer. We investigated the association of total coffee, caffeinated coffee, decaffeinated coffee, and tea consumption with risk of pancreatic cancer. METHODS: This stu

Diffusive-ballistic heat transport in thin films using energy conserving dissipative particle dynamics

Diffusive-ballistic heat transport in thin films was simulated using energy conserving dissipative particle dynamics (DPDe). The solution domain was considered to be two-dimensional with DPD particles distributed uniformly under constant temperature boundary conditions at the top and bottom walls and periodic boundaries at the side walls. The effects of phonon mean free path were incorporated by i

Depression and health-related quality of life in elderly patients suffering from heart failure and their spouses: a comparative study

Background: Little is known about the factors that influence the health outcome of elderly patients suffering from heart failure or the health of their spouses. The aim of this comparative study was to determine if older patients suffering from heart failure and their spouses experience similar levels of health-related quality of life (HRQOL) and depression. The aim was also to identify those fact

Människan på gott och ont : Freuds tragiska antropologi

Vårvintern 1915 författar Freud ett par essäer där han sammanfattar sina reflektioner över kriget, vilka han senare under året publicerar under rubriken ”Tidsligheter om krig och död”. Artikeln tar sitt avstamp i denna text och reflekterar över Freud som kultur- och civilisationskritiker i relation till vår europeiska samtid – hundra år efter att första världskriget bröt ut.

Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study

Objective: Previously, we observed an association between family history of type 1 diabetes and development of non-insulin-dependent diabetes. The aims of this study were to assess whether type 1 diabetes susceptibility gene variants explain this association and investigate the effect of the variants on insulin secretion and presence of glutamic acid decarboxylase autoantibodies (GADA) in nondiabe

Using 915 nm Laser Excited Tm3+/Er3+/Ho3+-Doped NaYbF4 Upconversion Nanoparticles for in Vitro and Deeper in Vivo Bioimaging without Overheating Irradiation

Successful further development of superhigh-constrast upconversion (UC) bioimaging requires addressing the existing paradox: 980 nm laser light is used to excite upconversion nanoparticles (UCNPs), while 980 nm light has strong optical absorption of water and biological specimens. The overheating caused by 980 nm excitation laser light in UC bioimaging is computationally and experimentally investi

Performance Analysis of Aluminum and Graphite Foam Heat Exchangers Under Countercurrent Arrangement

Due to the increasing power requirement and the limited available space in the vehicles, a countercurrent heat exchanger (HEX) is proposed for the position on the roof of the vehicle compartment. Furthermore, a new material, graphite foam with high thermal conductivity and low density, is a potential material for HEXs in vehicles. In order to evaluate the performance of the graphite foam HEX, the

Dystrophia Smolandiensis: a novel morphological picture of recurrent corneal erosions

Purpose: The aim of this study was to describe morphological changes in Dystrophia Smolandiensis, a corneal disease that is characterized by recurrent corneal erosive episodes and the formation of central corneal keloid-like opacities in approximately half of those affected. Methods: The corneas of seven affected individuals were examined using in-vivo confocal microscopy. Specimens of one primary

Control of an ideal activated sludge process in wastewater treatment via an ODE–PDE model

The activated sludge process (ASP), found in most wastewater treatment plants, consists basically of a biological reactor followed by a sedimentation tank, which has one inlet and two outlets. The purpose of the ASP is to reduce organic material and dissolved nutrients (substrate) in the incoming wastewater by means of activated sludge (microorganisms). The major part of the discharged flow throug

High-throughput method for the analysis of ethylenethiourea with direct injection of hydrolysed urine using online on-column extraction liquid chromatography and triple quadrupole mass spectrometry.

Ethylenethiourea (ETU) is of major toxicological concern, since in experimental animal studies, ETU has shown a large spectrum of adverse effects. High occupational exposure can be found among agricultural workers or during manufacturing of ethylenbisdithiocarbamates (EBDC). For the general public, sources of environmental exposure may be residues of ETU in commercial products, food and beverages.

The Multiple Streams Framework and the problem broker

John Kingdon's Multiple Streams Framework (MSF) constitutes a powerful tool for understanding the policy process, and more specifically, agenda-setting, through three separate streams: problems, policies and politics. This article argues that the MSF would benefit from further development of the problem stream. It introduces a clearer conception of agency into the problem stream by suggesting the

Arsenic Exposure through Drinking Water Is Associated with Longer Telomeres in Peripheral Blood

Inorganic arsenic is a strong carcinogen, possibly by interaction with the telomere length. The aim of the study was to evaluate how chronic arsenic exposure from drinking water as well as the arsenic metabolism efficiency affect the individual telomere length and the expression of telomere-related genes. Two hundred two women with a wide range in exposure to arsenic via drinking water (3.5-200 mu

Locomotives of local growth: The short- and long-term impact of railroads in Sweden

This paper studies the impact of railroads on 150 years of urban growth in Sweden, identifying the short- and long-term effects of a first wave of railroad construction. Difference-in-differences and instrumental variable estimates show that towns that gained access experienced substantial relative increases in population, though such growth mainly reflected a relocation of economic activity. Over

Assessment of the 3-D shape and mechanics of the proximal femur using a shape template and a bone mineral density image

Measurement of bone mineral density (BMD) by DXA (dual-energy X-ray absorptiometry) is generally considered to be the clinical golden standard technique to diagnose osteoporosis. However, BMD alone is only a moderate predictor of fracture risk. Finite element analyses of bone mechanics can contribute to a more accurate prediction of fracture risk. In this study, we applied a method to estimate the