OBJECTIVE:: To evaluate effect on comorbid disease and weight loss 5 years after Roux-en-Y gastric bypass (RYGB) surgery for morbid obesity in a large nationwide cohort. BACKGROUND:: The number patients having surgical procedures to treat obesity and obesity-related disease are increasing. Yet, population-based, long-term outcome studies are few. METHODS:: Data on 26,119 individuals [75.8% women,

In the quest for deciphering disease-associated biomarkers, high-performing tools for multiplexed protein expression profiling of crude clinical samples will be crucial. Affinity proteomics, mainly represented by antibody-based microarrays, have during recent years been established as a proteomic tool providing unique opportunities for parallelized protein expression profiling. But despite the pro

In this paper, we study how foreign ownership of Swedish companies affects employment and wages. To study these effects, we specify a model based onthe assumption that the Swedish labour market can be described as one wheretrade unions and employers bargain over employment and wages. Our hypothesis isthat bargaining power is affected by institutional settings and the ownership of thefirm. To test In this paper, we study how foreign ownership of Swedish companies affects employment and wages. To study these effects, we specify a model based on the assumption that the Swedish labour market can be described as one where trade unions and employers bargain over employment and wages. Our hypothesis is that bargaining power is affected by institutional settings and the ownership of the firm. To t

Some argue that the Stoics founded linguistics in the modern sense. The central notions of their understanding of language are found and preserved in the works of others, such as Diogenes Laertius, Sextus Empiricus and the work of the commentator Stephanos.This paper looks into the Stoic understanding of language and how the Greek verbal system fits into it. The Greek verbal system is put into the

Etzel Cardeña and Lauren Reid investigate how literature can open up different models of thinking about time. These models of time are brought to life by clips from the spectacular films of the one-and-only director and choreographer - Busby Berkeley.

The LIM-only protein Lmo2, originally identified as an oncogenic protein in human T cell leukemia, is essential for erythropoiesis. A possible role for Lmo2 in transcription during erythropoiesis has been investigated. Direct interaction of Lmo2 was observed in vitro and in vivo with the zinc finger transcription factor GATA-1, as well as with the basic helix-loop-helix (bHLH) transcription factor

The LMO2 gene associated with T cell acute leukaemia has been used as an example of a gene activated by association with the T cell receptor genes after chromosomal translocations. The gene is shown to encode a LIM protein which is involved in protein interactions and during normal haematopoiesis is necessary for erythroid development. LMO2 has been shown to cause tumours when aberrantly expressed

Experiments for measuring gas diffusion through porous alumina ceramics are described. With the gas in scattering media absorption spectroscopy (GASMAS) technique, gaseous oxygen signals are measured continuously during the gas diffusion process. It is experimentally demonstrated that the time-dependence of the transient oxygen signal is described by an exponential curve. Moreover, the effect on g

We develop a model to study tetraquark production in hadronic collisions. We focus on double parton scattering and formulate a version of the color evaporation model for the production of the X(3872) and of the T4c tetraquark, a state composed by the cc¯cc¯ quarks. We find that the production cross section grows rapidly with the collision energy s and make predictions for the forthcoming higher en

Den här rapporten analyserar bedömningsprocessen och bedömningskriterier i tillsättningsärenden av universitetslektorer vid Ekonomihögskolan vid Lunds universitet med särskilt fokus på sju tillsättningsärenden av universitetslektorer vid den Företagsekonomiska institutionen. Rapporten gör en genomgång av regelverket och lokala föreskrifter kring tillsättningar av universitetslektorer samt hur man

Background & Aims: BCAT1 initiates the catabolism of branched-chain amino acids. Here, we investigated the function of BCAT1 and its transcriptional regulatory mechanism in hepatocellular carcinoma (HCC). Methods: RNASeq was used to evaluate BCAT1 mRNA levels in HCC and normal matched specimens. After the exogenous expression of BCAT1 in BEL-7404 cells and the suppression of endogenous BCAT1 e

We have developed over the past years an experimental magnetic resonance imaging (MRI) and polarized gases compatible mechanical respirator for the study of the small experimental animal. The respirator has been successfully used for experiments both in the MRI setting for polarized (3)He, (19)F, and proton imaging as well as for functional measurements of the lungs. The new main pneumatic valve w

The influence of flip angle and flow velocity on the signal intensity achieved when imaging a hyperpolarized substance with a spoiled gradient echo sequence was investigated. The study was performed both theoretically and experimentally using hyperpolarized xenon dissolved in ethanol. Analytical expressions regarding the optimal flip angle with respect to signal and the corresponding signal level

PURPOSE: To evaluate MRI-based techniques for visual guidance, thermal monitoring, and assessment during transurethral ultrasound thermal therapy of implanted tumors in an in vivo canine prostate model.MATERIALS AND METHODS: Transmissible venereal tumors (TVT) were grown in the right lobe of the prostate in four dogs. High-temperature thermal therapy was selectively applied to the tumor-bearing lo

MR image nonuniformity can vary significantly with the spin-echo pulse sequence repetition time. When MR images with different nonuniformity shapes are used in a T1-calculation the resulting T1-image becomes nonuniform. As shown in this work the uniformity TR-dependence of the spin-echo pulse sequence is a critical property for T1 measurements in general and for ferrous sulfate dosimeter gel (FeGe