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In this work, the diblock copolymer methoxy-poly(ethylene glycol)-block-poly(ϵ-caprolactone) (MPEG-b-PCL) was synthesized with a block composition that allows this polymer in aqueous media to possess both an upper critical solution temperature (UCST) and a lower critical solution temperature (LCST) over a limited temperature interval. The value of the UCST, associated with crystallization of the P

Förklaringen till kronförsvagningen är enklare än vad de flesta tror, skriver nationalekonomerna Fredrik N G Andersson och Lars Jonung.

Previous research has focused on how governments and public authorities can limit civil society organisations’ (CSOs) autonomy by shrinking their operational civic space and their democratic functions. There has been less attention paid to how other external actors and types of pressure might restrict access to civic space and how it can induce coping responses on both an individual and organizati

The lion’s share of entrepreneurship research highlights conditions in core regions, while entrepreneurship in peripheral areas has been less studied. This longitudinal study aims at exploring the interplay between the peripheral contexts of island and archipelago communities and firm outcomes - paying special attention to spatial variations and non-linear temporal dimensions. We focus on the surv

Predictor screening rules, which discard predictors before fitting a model, have had considerable impact on the speed with which sparse regression problems, such as the lasso, can be solved. In this paper we present a new screening rule for solving the lasso path: the Hessian Screening Rule. The rule uses second-order information from the model to provide both effective screening, particularly in

Numerical validation is at the core of machine learning research as it allows to assess the actual impact of new methods, and to confirm the agreement between theory and practice. Yet, the rapid development of the field poses several challenges: researchers are confronted with a profusion of methods to compare, limited transparency and consensus on best practices, as well as tedious re-implementat

A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule's extent and cellular composition in 263 patients with colorectal cancer liver metastases to investigate its clinical significance and origin. We show that survival improves proportionally with increasing encapsulation and decreasing tumo

Methylglyoxal (MG) is a reactive and toxic compound produced in carbohydrate, lipid, and amino acid metabolism. The glyoxalase system is the main detoxifying route for MG and consists of two enzymes, glyoxalase I (GlxI) and glyoxalase II (GlxII). GlxI catalyzes the formation of S-d-lactoylglutathione from hemithioacetal, and GlxII converts this intermediate to d-lactate. A relationship between the

This paper presents a database with the probably most up-to date and reliable consumer price indices for a large sample of European countries since 1870. The database is a compilation but a contribution by going back to original or ignored works. For some Eastern European countries, where CPIs have been missing, new provisional indices are constructed. It critically examines historical CPIs in oft

Overactive bladder syndrome with and without urinary incontinence and related conditions, signs, and disorders such as detrusor overactivity, neurogenic lower urinary tract dysfunction, underactive bladder, stress urinary incontinence, and nocturia are common in the general population and have amajor impact on the quality of life of the affected patients and their partners. Based on the deliberati

Importance: Obsessive-compulsive disorder (OCD) is associated with adverse health-related outcomes. However, pregnancy and neonatal outcomes among women with OCD have been sparsely studied. Objective: To evaluate associations of maternal OCD with pregnancy, delivery, and neonatal outcomes. Design, Setting, and Participants: Two register-based cohort studies in Sweden and British Columbia (BC), Can

Context. β Pictoris is a young nearby system hosting a well-resolved edge-on debris disk, along with at least two exoplanets. It offers key opportunities for carrying out detailed studies of the evolution of young planetary systems and their shaping soon after the end of the planetary formation phase. Aims. We analyzed high-contrast coronagraphic images of this system, obtained in the mid-infrared

Using functional imaging and neural circuit reconstructions, a recent study reveals head direction neurons in the anterior hindbrain of zebrafish that resemble insect head-direction cells to a surprising degree.

Background: Gambling disorder is associated with increased suicidality, especially in women who also are more likely to have psychiatric comorbid disorders and more often have experiences of traumatic life events. Although suicidality is increased and several risk factors have been identified, knowledge of the suicidal process is lacking, especially for women. Aim: To explore the lived experiences

In addition to peripheral neuropathy of various manifestations, diabetes is also associated with central neuropathy. This can manifest as premature cognitive decline, although the role of hyperglycemia in this process remains ambiguous. Notwithstanding that the link between diabetes and cognitive decline was discovered 100 years ago, and has important clinical implications, this co-morbidity remai

This article examines the Norwegian climate fiction television series Okkupert [Occupied](2015–), focusing on the ways in which it reveals the complicity of Nordic subjects in an ecological dystopia. I argue that in illuminating this complicity, the series reimagines the Norwegian national self-conception rooted in a discourse of Norway’s exceptionalist relation to nature. I show how Norway’s gree

Addressing representations of Russia and neighbouring Eastern Europe in post-1989 Nordic cinemas, this ground-breaking volume investigates their hitherto-overlooked transnational dimension. Departing from the dark stereotypes that characterise much of ‘Eastern noir’, the author presents Russia and Eastern Europe as imagined spaces depicted with a surprisingly rich, but previously neglected, cinema

Paper 1Several problems emerge when a paperboard package is modeled by means of the nite element method. One of the issues that one has to deal with is the constitutive model of the paperboard. Paperboard and paper in general areorthotropic materials, which means that constitutive parameters in three orthogonal directions must be determined. Furthermore, the geometry of papersheets makes it dicult