Oorganiska karbonylkomplex med en antimalarisk ligand Under 2022 insjuknade 249 miljoner människor i Malaria, varav 608 000 avled. Malaria orsakas av parasiter från släktet Plasmodium och sprids via myggor. Redan på 1600-talet användes kinin, som extraherades från det sydamerikanska Kinaträdet, för att behandla Malaria. Fram till det tidiga 1900talet var kinin den huvudsakliga behandlingen för sjuAbstract Malaria, caused by the Plasmodium parasite infects hundreds of millions of people each year. Chloroquine is the commonly used drug therapy but resistance to the medication has been rising steadily. New antimalarial candidates have been found by creating inorganic complexes with different transition metals and chloroquine analogues as ligands. In this project, five new complexes were creat

In this master's thesis, my main objective is to broaden the understanding of early Franciscan spirituality. I achieve this by utilizing the sermons of Anthony of Padua as a source. By studying his sermons, we gain a deeper understanding of his thoughts. The research question of the thesis is: What is Anthony's perspective on poverty and wisdom based on his sermons? These two aspects of An

The purpose of this master thesis in practical theology is to investigate the reasons for choices of hymns made by parents baptising their children in the Church of Sweden. From earlier data on baptisms and hymns we do know which hymns are most commonly chosen, but no one to date has interviewed parents on their choices. The method used is semi structured interviews of eleven parents whose childre

Hyperbolic paraboloids, “hypars,” are special types of ruled surfaces. Their geometric properties provide them with loadbearing and stabilizing capacities, as well as distinct esthetic qualities. These attributes become evident in numerous applications in buildings, in many of which concrete or timber is used for the construction of the hypars. Hypars could also be relevant in the context of circu

A major difficulty in assessing road traffic safety is the scarcity of historical accident data. xxThis is a common problem in contexts where a certain level of safety has been reached or where exposure is low, such as mixed traffic conditions with different levels of transport automation. Recent studies have demonstrated how severe interactions between road users and/or road users and infrastruct

Background: The PI*S variant is one of the most prevalent mutations within alpha-1 antitrypsin deficiency (AATD). The risk of developing AATD-related lung disease in individuals with the PI*SS genotype is poorly defined despite its substantial prevalence. Our study aimed to characterize this genotype and its risk for lung disease and compare it with the PI*ZZ and PI*SZ genotypes using data from th

The ring-like peripheral light-harvesting complex 2 (LH2) expressed by many phototrophic purple bacteria is a popular model system in biological light-harvesting research due to its robustness, small size, and known crystal structure. Furthermore, the availability of structural variants with distinct electronic structures and optical properties has made this group of light harvesters an attractive

The translational stem cell research field has progressed immensely in the past decade. Development and refinement of differentiation protocols now allows the generation of a range of cell types, such as pancreatic β-cells and dopaminergic neurons, from human pluripotent stem cells (hPSCs) in an efficient and good manufacturing practice-compliant fashion. This has led to the initiation of several

Context. White-light stellar flares are proxies for some of the most energetic types of flares, but their triggering mechanism is still poorly understood. As they are associated with strong X and ultraviolet emission, their study is particularly relevant to estimate the amount of high-energy irradiation onto the atmospheres of exoplanets, especially those in their stars’ habitable zone. Aims. We u

Disruptions in energy homeostasis can lead to diseases like obesity and diabetes, affecting millions of people each year. Tanycytes, the adult stem cells in the hypothalamus, play crucial roles in assisting hypothalamic neurons in maintaining energy balance. Although tanycytes have been extensively studied in rodents, our understanding of human tanycytes remains limited. In this study, we utilized

We demonstrate experimentally nonequilibrium transport in unipolar quasi-1D hot electron devices reaching the ballistic limit at room temperature. The devices are realized with heterostructure engineering in nanowires to obtain dopant- and dislocation-free 1D-epitaxy and flexible bandgap engineering. We show experimentally the control of hot electron injection with a graded conduction band profile

The COVID-19 pandemic showed us that maintaining and increasing individual and community resilience is essential, particularly in cities. Access to urban green spaces such as parks and gardens supports resilience and well-being. Here, we studied how the pandemic influenced the attitudes towards and outcomes of urban box gardening in the city of Turku in Finland. We analyzed this small-scale social

Machine Learning (ML) algorithms are generally designed for scenarios in which all data is stored in one data center, where the training is performed. However, in many applications, e.g., in the healthcare domain, the training data is distributed among several entities, e.g., different hospitals or patients’ mobile devices/sensors. At the same time, transferring the data to a central location for