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Pupil size and search performance in low and high perceptual load

The ability to focus on a task while disregarding irrelevant information is an example of selective attention. The perceptual-load hypothesis argues that the occurrence of early or late selection mechanisms is determined by task-relevant perceptual load. Additionally, evidence shows that pupil size serves as proxy of locus coeruleus-norepinephrine (LC-NE) activity, a system associated with cogniti

Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition

Insulin-like growth factor-I (IGF-I) regulates cell proliferation and apoptosis, and is thought to play a role in tumour development. Previous prospective studies have shown that higher circulating concentrations of IGF-I are associated with a higher risk of cancers at specific sites, including breast and prostate. No prospective study has examined the association between circulating IGF-I concent

Transurethral resection of the prostate : Are we following the guidelines? - Outcomes from the Global Prevalence of Infections in Urology (GPIU) study

Transurethral resection of the prostate (TURP) is one of the most common urological procedures. With the increasing rate of multiresistant infections including urosepsis, it is essential for all surgeons to adhere to the relevant international guidelines to prevent infectious complications. The aim of this prospective, multinational, multicentre study was to evaluate compliance with recommended in

CA19-9 and apolipoprotein-A2 isoforms as detection markers for pancreatic cancer : a prospective evaluation

Recently, we identified unique processing patterns of apolipoprotein A2 (ApoA2) in patients with pancreatic cancer. Our study provides a first prospective evaluation of an ApoA2 isoform (“ApoA2-ATQ/AT”), alone and in combination with carbohydrate antigen 19–9 (CA19-9), as an early detection biomarker for pancreatic cancer. We performed ELISA measurements of CA19-9 and ApoA2-ATQ/AT in 156 patients

Ett pilgrimsbesök i Vadstena år 1432

During a fictional visit to Vadstena in the year 1432 we learn about indulgences, see the future insurgent Engelbrekt, hear the adventures of some shipwrecked Venetians, and listen to a sermon at the Birgittine abbey church.

Linking life-history theory and metabolic theory explains the offspring size-temperature relationship

Temperature often affects maternal investment in offspring. Across and within species, mothers in colder environments generally produce larger offspring than mothers in warmer environments, but the underlying drivers of this relationship remain unresolved. We formally evaluated the ubiquity of the temperature–offspring size relationship and found strong support for a negative relationshipacross a