Search results
Filter
Filetype
Your search for "*" yielded 533384 hits
RIFM fragrance ingredient safety assessment, p-isobutyl-α-methyl hydrocinnamaldehyde, CAS Registry Number 6658-48-6
A Damping Ratio Bound for Networks of Masses and Springs
The damping ratio is a key performance measure in systems that can be modelled as networks of masses and springs. We derive a lower bound on this quantity that applies to such networks when the masses are subject to viscous damping. The result allows the size of the damping ratio to be understood as a function of the system parameters. We use this to derive a decentralised criterion which, if sati
Mono endo-6- And bis endo,endo-12-N,N-diethylcarbamoyl derivatives of Tröger’s Base. Synthesis and exo-endo isomerization study
An efficient synthetic route to the mono-endo-6- and bis-endo,endo-6,12-N,N-diethylcarbamoyl derivatives of Tröger’s base (TB), endo-7 and endo-8, is reported. Studies of reaction time, proton source, and additive allowed establishment of optimized conditions for the conversion of exo-7 into the corresponding isomer endo-7. With a longer reaction time, the exo,exo-6,12 bis-carbamoyl derivative exo
Male Breast Carcinoma after Irradiation and Long-Term Phenothiazine Exposure : A Case Report
We present a young male patient with breast cancer having several risk factors likely acting in consort: irradiation of the breast for gynecomastia in adolescence and a life-long administration of phenothiazine for schizophrenia from the age of 16 years, with elevated serum prolactin level resulting in breast cancer development 24 years after irradiation.
Computing the boolean product of two n × n boolean matrices using o(N2) mechanical operations
We study the problem of determining the Boolean product of two n × n Boolean matrices in an unconventional computational model allowing for mechanical operations. We show that O(n2 ) operations are sufficient to compute the product in this model.
Significance of EGFR/HER2 Expression and PIK3CA Mutations in Giant Cell Tumour of Bone Development
Giant Cell Tumour of Bone (GCTB) is a rare bone tumour. Locally aggressive and recurrent, it might evolve into pulmonary metastases. Our present work is aimed at investigating the involvement of the epidermal growth factor receptor (ErbB) family and its downstream effectors in the development and recurrence of GCTB. For this purpose, we used a cohort of 32 GCTB patients and we evaluated the clinic
Imaging in gynecological disease (18) : clinical and ultrasound characteristics of urinary bladder malignancies
Objective: To describe the clinical and ultrasound characteristics of urinary bladder malignancies diagnosed on transvaginal ultrasound in women presenting with suspected gynecological problems. Methods: This was a multicenter retrospective study of women with a histological diagnosis of urinary bladder malignancy that was suspected on transvaginal ultrasound examination. The cases were collected
Understanding tenants’ responses to energy efficiency renovations in public housing in Sweden : From the resigned to the demanding
This study focuses on the experiences of tenants in renovation projects of public housing rental apartments in Sweden. Tenants’ perspectives are under-researched in the context of energy efficiency renovation projects, which is a considerable oversight given the many ways in which such projects impact their lives. The aim of the paper is to reveal rare qualitative insights into tenants’ experience
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans
Genomic instability is a characteristic of a majority of human malignancies. Chromosomal instability is a common form of genomic instability that can be caused by defects in mitotic checkpoint genes. Chromosomal aberrations in peripheral blood are also indicative of genotoxic exposure and potential cancer risk. We evaluated associations between inherited genetic variants in 33 mitotic checkpoint g
Photoresponses in the radiolar eyes of the fan worm Acromegalomma vesiculosum
Fan worms (Annelida: Sabellidae) possess compound eyes and other photoreceptors on their radiolar feeding tentacles. These eyes putatively serve as an alarm system that alerts the worm to encroaching threats, eliciting a rapid defensive retraction into their protective tube. The structure and independent evolutionary derivation of these radiolar eyes make them a fascinating target for exploring th
Time Trends in the Use of Coronary Procedures, Guideline-Based Therapy, and All-Cause Mortality following the Acute Coronary Syndrome in Patients with Schizophrenia
AIM: Schizophrenia is associated with high cardiovascular mortality predominantly as a result of acute coronary syndrome (ACS). The aim of this study is to analyze time trends of coronary procedures, guideline-based therapy, and all-cause mortality in patients diagnosed with schizophrenia.METHODS AND RESULTS: This Danish nationwide register-based study analyzed 734 patients with a baseline diagnos
Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causing Coronavirus Disease 19 (COVID-19), emerged at the end of 2019 and quickly spread to cause a global pandemic with severe socio-economic consequences. The early sequencing of its RNA genome revealed its high similarity to SARS, likely to have originated from bats. The SARS-CoV-2 non-structural protein 10 (nsp10) displays high sequ
Warming weathers changes the chemical composition of oat hulls
The current threats of climate change are driving attention away from the petrochemical industry towards more sustainable and bio‐based production processes for fuels and speciality chemicals. These processes require suitable low‐cost starting material. One potential material assessed here is the oat hull. Its overall chemical composition has so far not been fully characterized. Furthermore, it is
Durability and design parameters of a Steel/PEEK gear pair
The parameters necessary for the reliable design of PEEK gears were determined. The effect of a steel gear's surface on the polymer gear's wear was investigated. Values for the wear coefficient of a steel/PEEK gear pair in dry and lubricated conditions are proposed. Testing showed that, on average, grease lubrication extends the lifespan of PEEK gears by a factor of 1.23, while the additional trea
The role of beliefs, expectations and values in decision-making favoring climate change adaptation : implications for communications with European forest professionals
Beliefs, expectations and values are often assumed to drive decisions about climate change adaptation. We tested hypotheses based on this assumption using survey responses from 508 European forest professionals in 10 countries. We used the survey results to identify communication needs and the decision strategies at play, and to develop guidelines on adequate communications about climate change adBeliefs, expectations and values are often assumed to drive decisions about climate change adaptation. We tested hypotheses based on this assumption using survey responses from 508 European forest professionals in 10 countries. We used the survey results to identify communication needs and the decision strategies at play, and to develop guidelines on adequate communications about climate change ad
Agile product development process transformation to support advanced one-of-a-kind manufacturing : International Journal of Computer Integrated Manufacturing
ABSTRACT Increased competition in the global market has forced companies to diversify their product ranges to meet the customers? changing needs and adopt product development strategies for mass customization or even one-of-a-kind production, which inevitably requires designing modular products. Product modularity is achieved via platform-based systems, in which various combinations of different m
Deterministic Lateral Displacement : Challenges and Perspectives
The advent of microfluidics in the 1990s promised a revolution in multiple industries from healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous-flow microfluidic particle separation method discovered in 2004 that has been applied successfully and widely to the separation of blood cells, yeast, spores, bacteria, viruses, DNA, droplets, and more. Deterministic
RIFM fragrance ingredient safety assessment, 4-phenyl-3-buten-2-ol, CAS Registry Number 17488-65-2
Novel Methods for the Quantification of Dipeptidyl Peptidase 3 (DPP3) Concentration and Activity in Human Blood Samples
BACKGROUND: The ubiquitously expressed dipeptidyl peptidase 3 (DPP3) is involved in protein metabolism, blood pressure regulation, and pain modulation. These diverse functions of DPP3 are attributed to the degradation of bioactive peptides like angiotensin II. However, because of limitations in currently available assays for determination of active DPP3 in plasma, the exact physiological function