OBJECTIVE: To discover common genetic variants associated with poststroke outcomes using a genome-wide association (GWA) study. METHODS: The study comprised 6,165 patients with ischemic stroke from 12 studies in Europe, the United States, and Australia included in the GISCOME (Genetics of Ischaemic Stroke Functional Outcome) network. The primary outcome was modified Rankin Scale score after 60 to

Introduction: The purpose of this study was to investigate potential associations between body composition and current smoking in young healthy women from high-risk families. Cigarette smoke contains >7000 chemicals of which 69 are established carcinogens and smoke also acts as an aromatase inhibitor. Smoking is now recognized as a carcinogen for the breast and influences both risk and prognosis.

Fossil fuel companies’ existence is incompatible with the planet’s survival, says Bill McKibben Paris 2015 will be one step along the line, not the thing that solves all the problemsWe now have solutions we didn’t have 25 years ago, we should deploy them with all possible speed

AIMS: To evaluate the effect of adding insulin to sulphonylurea (SU) and the effect of SU withdrawal on glycaemic control in Type 2 diabetic patients who failed on treatment with SU alone.METHOD: One hundred and seventy-five patients were included in a placebo-controlled multicentre study. During phase I (4 months), premixed insulin was added to glibenclamide therapy; during phase II (1-4 months,

Despite the fact that the observed gradient in water content among the Galilean satellites is globally consistent with a formation in a circum-Jovian disk on both sides of the snowline, the mechanisms that led to a low water mass fraction in Europa (∼8%) are not yet understood. Here, we present new modeling results of solids transport in the circum-Jovian disk accounting for aerodynamic drag, turb

S2 has been observed for decades in comets, including comet 67P/Churyumov-Gerasimenko. Despite the fact that this molecule appears ubiquitous in these bodies, the nature of its source remains unknown. In this study, we assume that S2 is formed by irradiation (photolysis and/or radiolysis) of S-bearing molecules embedded in the icy grain precursors of comets and that the cosmic ray flux simultaneou

It is important to study the factors affecting estimates of wetness since wetness is crucial in climate change studies. The availability of digital elevation models (DEMs) generated with high resolution data is increasing, and their use is expanding. LIDAR earth elevation data have been used to create several DEMs with different resolutions, using various interpolation parameters, in order to comp

I senere tid har spørsmålet om ulvens oppførsel overfor mennesker og nær bebyggelse vært sentralt i diskusjonen om norsk ulveforvaltning. Det har blitt framholdt at en del ulver er nærgående, på den måten at de synes å oppsøke bebodde områder, og ikke viker unna i møte med mennesker. Det sies at nærgående ulver er skremmende, og bidrar til redusert livskvalitet. Denne studiens formål har vært å ka

Ökande rovdjurspopulationer innebär att fler människor kommer att beröras av de stora rovdjurens närvaro. Detta skapar hos en del människor oro och rädsla. Rovdjursförvaltningen behöver hitta olika vägar för att svara på allmänhetens oro. Syftet med föreliggande projekt var att utvärdera hur informationsmöten utformade enligt psykologiska principer inverkar på allmänhetens rädsla för att möta björ

This paper proposes a cohesive and comprehensive framework for perceptual product experience (PPE). The framework aims at bringing together the variety of perceptual experiences that we may have when encountering products and objects. Apart from the core sensorial, cognitive and affective modes, the framework takes into account that any experience has dimensions of presentation and representation,