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Genetic regulation of spermine oxidase activity and cancer risk : a Mendelian randomization study
Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention. Here we test causality of SMOX levels with cancer risk using a Mendelian randomization analysis. We performed a GWAS of spermidine/spermine ratio to
RIFM fragrance ingredient safety assessment, cyclohexadecanone, CAS Registry Number 2550-52-9
RIFM fragrance ingredient safety assessment, 3-propylidenephthalide, CAS Registry Number 17369-59-4
Evidence for genetic integration of mating behavior and morphology in a behaviorally plastic alternative reproductive tactic
Alternative reproductive tactics (ARTs) often exhibit more than one mating behavior depending on social context (i.e., behavioral plasticity). It has been hypothesized that by constraining an ART from reaching optimal morphological states, intralocus tactical conflict could promote the maintenance of behavioral plasticity in ARTs, rather than the use of a fixed mating behavior to match an optimal
Coordination at the 10-year mark of the JHLSCM–from global response to local preparedness
Purpose: At the inception of the Journal of Humanitarian Logistics and Supply Chain Management (JHLSCM), logistics coordination was identified as important, both in practice and research, but few studies on the topic had been published. Ten years later, many, if not most, papers in the journal mention the topic. So the picture has changed, but to what extent? This paper discusses how coordination
Postoperative Endophthalmitis in Immediate Sequential Bilateral Cataract Surgery : A Nationwide Registry Study
Purpose: To report the incidence of postoperative endophthalmitis (PE) after immediate sequential bilateral cataract surgery (ISBCS) in Sweden. Design: Retrospective cohort registry study. Participants: Patient data from 1 457 172 cataract extractions, including 1 364 934 unilateral surgeries and 92 238 ISBCSs. Methods: Endophthalmitis cases reported to the Swedish National Cataract Register (NCR)
RIFM fragrance ingredient safety assessment, cinnamyl propionate, CAS Registry Number 103-56-0
RIFM fragrance ingredient safety assessment, p-menthan-2-one, CAS Registry number 499-70-7
Remissyttrande: Effektivare tillsyn över diskrimineringslagen – aktiva åtgärder och det skollagsreglerade området (SOU 2020:79)
The case for ending evaluation
RIFM fragrance ingredient safety assessment, 2-hexylidenecyclohexan-1-one, CAS Registry Number 16429-07-5
RIFM fragrance ingredient safety assessment, ethyl heptanoate, CAS Registry Number 106-30-9
Dyspnoea-12 and Multidimensional Dyspnea Profile : Systematic Review of Use and Properties
Context: The Dyspnoea-12 (D-12) and Multidimensional Dyspnea Profile (MDP) were specifically developed for assessment of multiple sensations of breathlessness. Objectives: This systematic review aimed to identify the use and measurement properties of the D-12 and MDP across populations, settings and languages. Methods: Electronic databases were searched for primary studies (2008-2020) reporting us
RIFM fragrance ingredient safety assessment, caryophyllene acetylated, CAS Registry Number 75975-83-6
Changes in numbers and distribution of wintering waterbirds around Gotland 1969–2020
THE COASTAL AREAS of the island of Gotland in the center of the Baltic Sea is an important wintering site for water-birds in Sweden. Gotland offers extensive areas of shallow feeding grounds and, due to its location, some open waters remain available even during harsh winters. Wintering waterbirds have been counted annually on the island since the start of the international waterbird counts in 196
Grazing incidence small angle neutron scattering as a tool to study curved biomembranes on nanostructured surfaces
Curvature in lipid-based biomembranes provides compartmentalization in cells and can act as regulator of biological activity in living systems. The study of these biomembranes require novel model systems and new methods. In this work I have used a supported phospholipid bilayer on a hexagonal array of silicon nanowires. The nanowires impose curvature on the supported lipid bilayer and the resultin
Analysis on breakup dynamics of hydrogen taylor bubble formation in a cross-junction microchannel
The pinch-off dynamics during hydrogen bubble formation was experimentally investigated in a cross-junction microchannel. A binarization interface recognizing and key frame tracking method was established. By analyzing the breakup dynamics through spatial and time domains, the effects of interfacial tension and viscosity on hydrogen bubble pinch-off were revealed. A transitional stage between a li
Is the Nagoya Protocol designed to conserve biodiversity?
We have entered a monumental era in terms of realizing the impact of biodiversity loss on our everyday lives. We suffer from the consequences of biodiversity loss due to overexploitation of natural resources as we continue failing to restore biodiversity. One of the major consequences of biodiversity loss is the emergence of global pandemics. We are in urgent need of realizing the full potential o
Decreased Pain Sensitivity and Alterations of Cerebrospinal Fluid and Plasma Inflammatory Mediators After Total Hip Arthroplasty in Patients with Disabling Osteoarthritis
Background: Proinflammatory mechanisms are implicated in pain states. Recent research indicates that patients with osteoarthritis (OA) with signs of central sensitization exhibit elevated cerebrospinal fluid (CSF) levels of interferon gamma-induced protein 10 (IP-10), Fms-related tyrosine kinase 1 (Flt-1), and monocyte chemoattractant protein 1 (MCP-1).Methods: The current prospective cohort study