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Dabigatran, rivaroxaban and apixaban vs. high TTR warfarin in atrial fibrillation

Introduction: New oral anticoagulants are non-inferior compared with warfarin regarding stroke prevention in atrial fibrillation, with similar or decreased risk of bleeding. However, it is unclear whether high TTR warfarin is as effective and safe as NOACs. Our objective was to investigate efficacy and safety of apixaban, dabigatran or rivaroxaban compared with warfarin in clinical practice. Mater

Chernobyl as the Beginning of the End of the Soviet Union

The belief in technology was fundamental in Soviet culture. When the nuclear reactor exploded and harvested souls and spread illness throughout a vast area, over the course of many years, an image of the collapse of the Soviet Union was thereby created. Chernobyl became an image of the apocalypse of communism

Self-reported nonsuicidal self-injury (NSSI) and sex as self-injury (SASI) : Relationship to abuse, risk behaviors, trauma symptoms, self-esteem and attachment

This study focuses on a conceptually unexplored behavior among adolescents who report deliberately using sex as a means of self-injury. In a large high school-based sample (n = 5743), adolescents who engaged in sex as self-injury (SASI, n = 43) were compared to adolescents who reported direct nonsuicidal self-injury (NSSI, n = 933) and those who reported both NSSI and SASI (n = 82). Results showed

A Western dietary pattern is prospectively associated with cardio-metabolic traits and incidence of the metabolic syndrome

The aim of this study was to derive dietary patterns associated with cardio-metabolic traits and to examine whether these predict prospective changes in these traits and incidence of the metabolic syndrome (iMetS). Subjects from the Malmö Diet and Cancer Study cardiovascular cohort without cardio-metabolic disease and related drug treatments at baseline (n 4071; aged 45-67 years, 40 % men) were in

The combined effects of FADS gene variation and dietary fats in obesity-related traits in a population from the far north of Sweden : the GLACIER Study

Background: Recent analyses in Greenlandic Inuit identified six genetic polymorphisms (rs74771917, rs3168072, rs12577276, rs7115739, rs174602 and rs174570) in the fatty acid desaturase gene cluster (FADS1-FADS2-FADS3) that are associated with multiple metabolic and anthropometric traits. Our objectives were to systematically assess whether dietary polyunsaturated fatty acid (PUFA) intake modifies

Acute inflammatory biomarker responses to diffuse traumatic brain injury in the rat monitored by a novel microdialysis technique

Neuroinflammation is a major contributor to the progressive brain injury process induced by traumatic brain injury (TBI), and may play an important role in the pathophysiology of axonal injury. The immediate neuroinflammatory cascade cannot be characterized in the human setting. Therefore, we used the midline fluid percussion injury model of diffuse TBI in rats and a novel microdialysis (MD) metho

Constructing Authority in Times of Crisis : A Genre Analysis of Government Crisis Communication in China

Purpose: This study investigates how the Chinese government generates authority during a crisis through discursive practices expressed in social media. Design/methodology/approach: Using the theoretical framework of authority and the method of genre analysis, this study examined the top 100 forwarded posts on Weibo about a highprofile murder to determine the mechanisms involved in generating autho

Warfarin monitoring with viscoelastic haemostatic assays, thrombin generation, coagulation factors and correlations to Owren and Quick prothrombin time

The anticoagulant warfarin is commonly monitored with prothrombin time (PT). Viscoelastic haemostatic assays (VHA) are primarily used in situations of acute bleeding to guide haemostatic therapy. Much research has focused on VHA monitoring of new oral anticoagulants. However, many patients are still anticoagulated with warfarin and effect of warfarin anticoagulation on VHA is uncertain. The aim of

Differences in attenuation pattern in myocardial SPECT between CZT and conventional gamma cameras

Background: In myocardial perfusion imaging (MPI), single-photon emission tomography (SPECT) soft-tissue attenuation by the abdomen, breasts, and lateral chest wall may create artifacts that mimic true perfusion defects. This may cause misdiagnosis of myocardial perfusion. The aim of the present study was to compare the localization, extent, and depth of attenuation artifacts in MPI SPECT for a mu

A tool for sourcing sustainable building renovation : The energy efficiency maturity matrix

The success of sustainable building renovation is inevitably dependent on the capabilities of the involved stakeholders throughout the entire project. Therefore, any building client with intentions of sustainable building renovations must reflect on sourcing the adequate capabilities for a sustainable renovation project. The question in focus is: how to facilitate a sourcing strategy for energy-ef

Transgender and gender diverse people's experience of non-transition-related health care in Sweden

Introduction: The transgender population is a marginalized group in society and research suggests that they experience significant barriers when accessing health care. However, little is known about transgender and gender-diverse people and their experiences of encounters with healthcare professionals in Sweden. Aim: To explore transgender and gender-diverse people's experiences of accessing healt

Mitt och ditt : etnologiska perspektiv på ägandets kulturella betydelse

Boken syftar till att öka kunskapen och förståelsen för ägandets kulturella betydelse och organisation. Hur sociala relationer, maktförhållanden, identiteter, ideal och normer påverkas och påverkar vad som uppfattas som mitt, ditt och vårt diskuteras med hjälp av aktuell etnologisk forskning om gemenskapande och gränser i villaträdgården och måltiden, mikropraktiker i samband med lånade prylar, cy

Assistive technology policy : a position paper from the first global research, innovation, and education on assistive technology (GREAT) summit

Increased awareness, interest and use of assistive technology (AT) presents substantial opportunities for many citizens to become, or continue being, meaningful participants in society. However, there is a significant shortfall between the need for and provision of AT, and this is patterned by a range of social, demographic and structural factors. To seize the opportunity that assistive technology

Identification and characterization of diverse coherences in the Fenna–Matthews–Olson complex

The idea that excitonic (electronic) coherences are of fundamental importance to natural photosynthesis gained popularity when slowly dephasing quantum beats (QBs) were observed in the two-dimensional electronic spectra of the Fenna–Matthews–Olson (FMO) complex at 77 K. These were assigned to superpositions of excitonic states, a controversial interpretation, as the strong chromophore–environment

Wideband Sparse Reconstruction for Scanning Radar

Recently, the generalized sparse iterative covariance-based estimation algorithm was extended to allow for varying norm constraints in scanning radar applications. In this paper, further to this development, we introduce a wideband dictionary framework which can provide a computationally efficient estimation of sparse signals. The technique is formed by initially introducing a coarse grid dictiona