We identified apolipoprotein E (ApoE) as one of the proteins that are found in complex with complement component C4d in pooled synovial fluid of rheumatoid arthritis (RA) patients. Immobilized human ApoE activated both the classical and the alternative complement pathways. In contrast, ApoE in solution demonstrated an isoform-dependent inhibition of hemolysis and complement deposition at the level

The European Spallation Source requires a pulsed linac with an average beam power on the target of 5 MW, which is about five times higher than the most powerful spallation source in operation today. Over 97 % of the acceleration occurs in superconducting cavities. ESS will be the first accelerator to employ double spoke cavities to accelerate beam. Accelerating gradients of 9 MV/meter is required

This scientific note aims to briefly introduce the concept of urban hibernation, published recently (September 2015) in an article with the same name in European Planning Studies (Routledge). By outlining some general characteristics, the purpose of this note is merely to put the reader’s attention to this concept, whom we remit to the original article for a comprehensive walk-through. The reason

We discuss γ ∗γ ∗→ ηc(1S) ; ηc (2S) transition form factor for both virtual photons. The general formula is given. We use difierent models for the cc̄ wave function obtained from the solution of the Schrödinger equation for diffierent cc̄ potentials: harmonic oscillator, Cornell, logarithmic, power-law, Coulomb and Buchmüller{Tye. We showed some examples of wave functions in the Light Front repres

There is an increasing demand from the user community for high quality FEL radiation. The spectrum of this radiation can prove to be a useful tool in characterizing the FEL process. Starting from a tool initially developed at FERMI we extend its capabilities to be able to analyze the modal components of the FEL spectrum. In this paper we will describe and compare two different figures of merit and

Due to the stochastic nature of SASE radiation its longitudinal coherence is limited to a small fraction of the electron bunch. By pre-bunching the electrons before entering a radiator, the FEL radiation is ensured to have the same initial phase all through the bunch. Echo enabled harmonic generation (EEHG) is a technique that, by cleverly using two modulators and two dispersive sections, creates

Background Some evidence suggests that chronic kidney disease is a risk factor for lower-extremity peripheral artery disease. We aimed to quantify the independent and joint associations of two measures of chronic kidney disease (estimated glomerular filtration rate [eGFR] and albuminuria) with the incidence of peripheral artery disease. Methods In this collaborative meta-analysis of international

Aim: To examine international time trends in the incidence of renal replacement therapy (RRT) for end-stage renal disease (ESRD) by primary renal disease (PRD). Methods: Renal registries reporting on patients starting RRT per million population for ESRD by PRD from 2005 to 2014, were identified by internet search and literature review. The average annual percentage change (AAPC) with a 95% confide