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Cerebrovascular lesions in stroke-prone spontaneously hypertensive rats

The cerebrovascular lesions of severe chronic hypertension were studied by light microscopy in perfusion-fixed, subserially sectioned brains from stroke-prone spontaneously hypertensive rats (SHRSP). The leakage and spread of plasma proteins were visualized by immunohistochemical detection of extravasated fibrinogen and by using an exogenous marker (Evans blue injected i.v.) for blood-brain barrie

Zero-range potentials with internal structures and the inverse scattering problem

The inverse scattering problem on the half-axis is solved for scattering matrices which result from scattering on a zero-range potential with an internal structure. The solutions are constructed as pointwise limits of Bargmann potentials and form a one-parameter family, We obtain a class of potentials decreasing slowly at infinity.

On the geometry of the Gauss map of conformal foliations by lines

Let F be an oriented conformal foliation of connected, totally geodesic and 1-dimensional leaves in Rn+1. We prove that if n greater than or equal to 3 then the Gauss map phi: U --> S-n of F is a non-constant n-harmonic morphism if and only if it is a radial projection.

Lake productivity and water chemistry as governors of the uptake of persistent pollutants in fish

Factors influencing uptake and levels of persistent pollutants (PCBs, p,p'-DDE) were investigated in 341 northern pike from 61 lakes in southern Scandinavia. Although the inflow of pollutants from the atmosphere was similar throughout the area studied, large differences in levels of PCBs and DDE in predatory fish were found between lakes. The factors primarily responsible for this variation appear

Left atrial appendage outflow velocity index is superior to conventional criteria for prediction of maintenance of sinus rhythm after cardioversion. An echocardiographic study in patients with atrial fibrillation of a few months' duration

OBJECTIVE: To investigate whether left atrial appendage outflow velocity alone or in relation to left atrial diameter is a superior predictor of sinus rhythm maintenance after cardioversion compared with traditional clinical or echocardiography parameters. DESIGN: Sixty-two patients with their first episode of atrial fibrillation were examined using echocardiography before DC-cardioversion. At one

Cognitive modeling with context sensitive reinforcement learning

We describe how a standard reinforcement learning algorithm can be changed to include a second contextual input that is used to modulate the learning in the original algorithm. The new algorithm takes the context into account during relearning when the previously learned actions are no longer valid. The algorithm was tested on a number of cognitive experiment and shown to reproduce the learning in

Soy product consumption in 10 European countries: the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Objective:. The aim of this study was to describe the variation of soy product intake in 10 European-countries by using a standardised reference dietary method. A subsidiary aim was to characterise the pattern of soy consumption among a sub-group of participants with a habitual health-conscious lifestyle (HHL), i.e. non-meat eaters who are fish eaters, vegetarians and vegans. Design: A 24-hour die

Heat Flow in Building Components, Experiment and Analysis

Three building components exposed to natural climate were studied: a dynamic insulation in the ceiling of a house, an outer wall and one window in the same wall. The term dynamic insulation implies that part of the inlet or exhaust air passes through the insulation of a house. A house with dynamic insulation was continuously measured for approximately a year and a half. The performance of the dyna

Vacuum-assisted closure therapy guided by C-reactive protein level in patients with deep sternal wound infection.

BACKGROUND: Deep sternal wound infection is a serious and potentially lethal complication of cardiac surgery when performed through a median sternotomy. We describe the outcome of a new treatment strategy with C-reactive protein level-guided vacuum-assisted closure used at our department. METHODS: Data from 16 consecutive adult patients who had deep sternal wound infections after cardiac surgery w

Electroatriography - Time-frequency analysis of atrial, fibrillation from modified 12-lead ECG configurations for improved diagnosis and therapy

Current atrial fibrillation (AF) management guidelines suggest that initially a decision must be made to apply either a rate control or rhythm control strategy in the individual patient. However, patients' selection remains substantially empirical and the strategy initially chosen often proves unsuccessful and alternative therapies must be adopted. Thus, it seems desirable to develop and apply tes

Ionic binding of C3 to the human pathogen Moraxella catarrhalis is a unique mechanism for combating innate immunity

Moraxella catarrhalis ubiquitous surface proteins A1 and A2 (UspA1/A2) interfere with the classical pathway of the complement system by binding C4b-binding protein. In this study we demonstrate that M. catarrhalis UspA1 and A2 noncovalently and in a dose-dependent manner bind both the third component of complement (C3) from EDTA-treated serum and methylamine-treated C3. In contrast, related Moraxe

Retinal nitro blue tetrazolium staining and catalase activity in rat models of diabetes

BACKGROUND: Recent studies have suggested that reactive oxygen species may be involved in the development of diabetic retinopathy. METHODS: Nitro blue tetrazolium (NBT) staining, a marker of reductants which may be induced by free radicals such as superoxide, and catalase activity, as an indirect measure of hydrogen peroxide (H2O2) generation, were studied in the rat retina in three conditions kno

Detection of autonomic modulation in permanent atrial fibrillation

A new signal processing method for the detection of cyclic variations in atrial fibrillation frequency is presented. The objective was to investigate whether or not respiration, through the autonomic nervous system, modulates the fibrillation frequency in patients with permanent atrial fibrillation. A group of eight patients with permanent atrial fibrillation, atrioventricular block III and a perm