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The use of consultants in the public sector is a growing field of study, but their influence in the energy sector remains underexplored. Public agencies face significant pressure to design, implement, and coordinate the energy transition. Thus, they increasingly rely on consultants to provide specialised expertise, additional capacity, and external legitimacy. This article examines how consultants
Utvecklingen av ett hållbart energisystem kräver en omställning mot mer resurseffektiva och cirkulära lösningar. Industriell och urban symbios har lyfts fram som en central strategi för att minska energianvändning, utsläpp och resursförbrukning genom att koppla samman material- och energiflöden mellan olika aktörer. Trots stor potential har implementeringen varit begränsad, och många initiativ sta
Factor IX (FIX) is a relatively small molecule (55 kDa) that distributes physiologically beyond the plasma pool into the extravascular space. This contrasts with factor VIII, which is confined to the bloodstream as a consequence of its larger size (∼300 kDa) and binding to von Willebrand factor. The extravascular distribution of FIX may be significant in relation to factor replacement therapy in p
Background Subcutaneous emicizumab prophylaxis is increasingly used for early prophylaxis in infants with severe hemophilia A (SHA). Although the HAVEN 7 trial (NCT04431726) reported on 55 infants with SHA, real-world information regarding factor (F)VIII exposure, inhibitor development, and bleeding on this age group remains limited. Objectives To describe FVIII exposure, model-based annualized bl
In their book Barnavård till salu: förlossningshem och barnpensionat 1900-1975 (translated as‘Childcare for sale: maternity homes and children’s boarding houses 1900-1975’), Johanna Sköldand Johanna Sjöberg analyse the commercial market for childcare which existed in tandem with,at first, the philanthropic and, later, the increasingly state-subsidised childcare institutions whichwere part of Swede
This artistic research project asks: How can a care-oriented artistic practice based on listening facilitate the shaping of lived experience into artistic material? The question has developed through a research process spanning 2020–2026 and through three artistic projects: My Deer Hunter (2020), Stille slag (Quiet Beats) (2021) and Lyttekor (Listening Choir) (2024–25). Each project takes lived ex
INTRODUCTION: Guidelines often recommend patient education in the management of hip or knee replacement, despite evidence of its effectiveness is scarce. The aim of this study was to assess the effectiveness of postoperative patient education on pain, function, quality of life, and psychosocial issues.METHODS: We performed a systematic review and meta-analysis of RCTs investigating the effects of
BACKGROUND: The quality of evidence supporting recommendations for conservative hip osteoarthritis management limits the treatment options available to patients prior to surgery. The care individuals receive prior to their eventual total hip replacement (THR) is likely to be variable and complex. These long-term care patterns remain undefined.METHODS: A population-based retrospective case-control
OBJECTIVES: To map how sleep has been assessed in osteoarthritis (OA) and/or inflammatory arthritis (IA), and to synthesise the evidence on the prevalence, characteristics, and relationships between sleep disturbances and these conditions.METHODS: We conducted a scoping review following the JBI guidelines and reported it following the PRISMA extension guidelines for scoping reviews (PRISMA-ScR). M
OBJECTIVE: Use of neuropathic pain medications is increasing in OA patients, but it is unclear if this is driven by OA-specific use or presence of comorbidities. We aimed to investigate the use of neuropathic pain medications attributable to knee and hip OA pain.DESIGN: We included all residents aged ≥35 years of the Skåne region, Sweden, in 2018. After exclusions, 645,991 individuals remained, wh
OBJECTIVE: To estimate the associations of diabetes and/or hypertension with (i) initiating opioid therapy and (ii) progressing to long-term opioid use, after an osteoarthritis (OA) diagnosis.METHODS: Population-based open cohort study using Swedish registers. We followed 48,778 opioid-naïve individuals, aged 35-75, with incident OA between 2008 and 2019 in the Skåne region. The associations of di
Large language models (LLMs) can generate executable source code from natural language prompts, fueling a fast-growing ecosystem of AI-assisted software development tools. However, evaluation practices for these systems remain largely one-dimensional, focusing almost exclusively on functional correctness. This narrow lens overlooks critical aspects of software performance and readiness, notably ru
Background: Myocardial injury activates the complement lectin pathway (LP) in acute coronary syndrome (ACS) and LP inhibition improved cardiac function in experimental studies, suggesting a direct pathogenic role. The clinical consequences of LP activation are insufficiently defined. We investigated how plasma levels of the LP activators mannose-binding lectin (MBL) and ficolin-2 (FCN2) relate to
For centuries there has been great interest in the dissolution of cellulose. Regarding industrial uses, water-based solvents remain the primary focus. It has long been known that concentrated solutions of sodium hydroxide can dissolve significant amounts of cellulose, but only at temperatures well below ambient conditions. This review discusses a general thermodynamic framework for cellulose disso
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease targeting multiple organ systems, including the nervous system. The cerebellum may be involved in prevalent neuropsychiatric manifestations, such as depression and cognitive dysfunction, alongside other prevalent SLE manifestations such as pain and fatigue. We aim to compare cerebellar volumes in SLE patients and healt
Background: Adenosquamous carcinoma of the pancreas (ASCP) is a rare and aggressive subtype of pancreatic cancer with a dismal prognosis. Futility in ASCP has been inadequately studied. The aim is to assess the incidence of futility in ASCP cases within a European cohort. Methods: Retrospective, multicenter European study including all consecutive patients who underwent surgery for ASCP between 20
Natural enemies provide an important ecosystem service, limiting the population densities of insect pests in agricultural crops. In white clover (Trifolium repens L.) grown for seed production, the white clover seed weevil (Protapion fulvipes Geoffrey) is a major factor limiting seed yields. We explored the abundances and parasitism rates of P. fulvipes in relation to local field management and la
AIMS: Inflammasome activation has emerged as a promising therapeutic target to reduce residual cardiovascular (CV) risk in patients on guideline lipid-lowering therapy. IL-1β and IL-6 have been intensively studied, whereas the role of the inflammasome-related cytokine IL-18 has gained less attention. Here we aimed to assess the associations of IL-18 with risk of coronary events and severity of ath
AIMS: Aging is a major risk factor for cardiovascular disease (CVD) and is also linked to a functional decline of the immune system. B cells contribute to atherosclerosis progression by antibody secretion, antigen presentation and T-cell regulation. During aging, CD11c+CD21low B cells accumulate, but it is unclear whether these age-associated B cells (ABCs) are linked with incident cardiovascular
