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The value of travel guidebooks in the digital age

Travel guidebooks are both travel information channels and objects of consumption. In contemporary tourism, Information and Communication Technologies (ICT) make information abundant and mostly free of charge. Therefore, as tourists still buy them, there must be something that makes guidebooks a valuable object. This research aims at understanding the value of travel guidebooks in the digital age.

Determination of the Distance Between the Cytochrome and Dehydrogenase Domains of Immobilized Cellobiose Dehydrogenase by Using Surface Plasmon Resonance with a Center of Mass Based Model

Changes in the tertiary conformation of adsorbed biomolecules can induce detectable shifts (Δθr) in the surface plasmon resonance (SPR) angle. Here it is shown how to calculate the corresponding shifts in the adsorbate's center of mass (Δzavg) along the sensing surface normal from the measured Δθr. The novel developed model was used for determining the mean distance between the cytochrome (CYT) an

Radical radiotherapy for prostate cancer : patterns of care in Sweden 1998–2016

Introduction: Radiotherapy is an established treatment option for prostate cancer (PCa), both as primary treatment and secondary treatment after radical prostatectomy (RP). Since 1998, detailed data on radiotherapy delivered to Swedish men with PCa (e.g. treatment modalities, absorbed doses, fractionation) have been collated within PCa data Base Sweden (PCBaSe). This study reports patterns of radi

The role of advocacy in critical care nursing : a caring response to another

With the aim of clarifying critical care nursing, six critical care nurses, working in a Swedish intensive care unit (ICU) were each asked to narrate a care situation with which they had been satisfied or dissatisfied. The stories were tape-recorded and analysed using a phenomenological-hermeneutic approach inspired by the philosophy of Ricoeur. The themes uncovered in the analysis describe the nu

Accurate solution-adaptive finite difference schemes for coarse and fine grids

We introduce solution dependent finite difference stencils whose coefficients adapt to the current numerical solution by minimizing the truncation error in the least squares sense. The resulting scheme has the resolution capacity of dispersion relation preserving difference stencils in under-resolved domains, together with the high order convergence rate of conventional central difference methods

Yttrande över remissen: En ny Riksbankslag (SOU 2019:46)

Lunds universitet har uppmanats att ge synpunkter på rubricerad remiss. Universitetet lämnar här följande kommentarer vilka har utarbetats vid Ekonomihögskolan vid Lunds universitet av docent Fredrik N G Andersson och professor emeritus Lars Jonung. Inflationsmålet infördes för över 25 år sedan. Villkoren för att bedriva penningpolitik har förändrats på ett omvälvande sätt under detta kvartssekel.

Identification of the high risk hip fracture patients

Background: Hip fractures are common in older individuals entailing considerable risk of morbidity and mortality. Instruments are needed to enhance risk stratification of hip fracture patients. There is limited knowledge of the role of biomarkers as risk prognosticators for mortality in hip fracture patients.Aims: We assessed how well two well known risk stratification tools performed in a cohort

Six commonly used empirical body surface area formulas disagreed in young children undergoing corrective heart surgery

Aim: Formulas for empirical body surface area (BSA), which is used to estimate body size and standardise physiological parameters, may disagree in children. We compared six commonly used BSA formulas—Du Bois, Boyd, Costeff, Haycock, Meban and Mosteller—in a surgical cohort. Methods: This retrospective single-centre cohort study comprised 68 children who had corrective heart surgery at Skåne Univer

Imagination

Imagination is a human capacity that reproduces and transforms experiences and thoughts. The capacity is manifested in children’s pretend play and is an important part of adults’ ability to process the past, and to plan the future. A first step in the development of imagination is the ability to represent objects and events and to change these representations into alternatives to reality. For adap

Transsynaptic tracing and its emerging use to assess graftreconstructed neural circuits

Fetal neural progenitor grafts have been evaluated in preclinical animal models of spinal cord injury and Parkinson’s disease for decades, but the initial reliance on primary tissue as a cell source limited the scale of their clinical translatability. With the development of robust methods to differentiate human pluripotent stem cells to specific neural subtypes, cell replacement therapy holds ren

Coordination crosslinking of helical substituted oligoamide nanorods with Cu(II)

Substituted oligoamides are short sequences of unnatural amino acids. Oligoamides made entirely of β3 amino acids yield helical monomers that, if N-acylated, assemble into nanorod structures via a supramolecular assembly motif. In this work, coordination crosslinking was used to create complex nanomaterials from oligoamides WKLWEL (KE) and WELWEL (EE) (the letters denote the analogous α-amino acid

Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice

AIMS/HYPOTHESIS: Obesity during pregnancy increases offspring type 2 diabetes risk. Given that nearly half of women of child-bearing age in many populations are currently overweight/obese, it is key that we improve our understanding of the impact of the in utero/early life environment on offspring islet function. Whilst a number of experimental studies have examined the effect of maternal obesity

Physical exercise as a preventive strategy for disorders affecting the brain. The effect on neuroinflammation.

Physical activity is associated with lower risks of developing dementia, Parkinson’s disease (PD) and depression. Furthermore, being physically active prior to brain ischemia appears to help the recovery process. However, previous studies do not differentiate between the two most common forms of dementia, Alzheimer’s disease (AD) and vascular dementia (VaD), when it comes to the association betwee

Hyperparathyroidism and parathyroidectomy in patients on renal replacement therapy

Background. Secondary hyperparathyroidism (sHPT) is characterized by over function of the parathyroid glands and disturbances in mineral metabolism as a result of renal failure. It is common among patients with end-stage renal disease (ESRD) and it often persists after successful renal transplantation. sHPT is associated with osteoporosis and cardiovascular morbidity and mortality. There are two mBackground. Secondary hyperparathyroidism (sHPT) is characterized by over function of the parathyroid glands and disturbances in mineral metabolism as a result of renal failure. It is common among patients with end-stage renal disease (ESRD) and it often persists after successful renal transplantation. sHPT is associated with osteoporosis and cardiovascular morbidity and mortality. There are two m