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The use of ultra-high frequency ultrasound in identifying aganglionosis in Hirschsprung’s disease

To make surgery more precise and to shorten anesthesia-times for children undergoing surgery for Hirschsprung’s disease, ultra-high frequency ultrasound (UHFUS) has been suggested to replace peroperative biopsy. The study’s aim was to determine quantitatively whether aganglionic and ganglionic bowel segments could be distinguished by UHFUS. Bowel specimens of 23 children operated on for rectosigmo

Equality of specialist orthodontic care for adolescents in the Swedish public dental service : a cohort study

Background: In Sweden, dental care for children and adolescents, including specialist orthodontic treatment, is publicly funded. This study aims to analyze the impact of sociodemographic factors on the distribution of publicly funded specialist orthodontic treatment in a mid-sized Swedish region. Methods: A registry-based cohort study was conducted in Region Östergötland, including individuals bor

Characterization of the Mmalton carrier’s cohort within the EARCO (European Alpha- 1 Antitrypsin Research Collaboration) registry

Introduction: The PI*Mmalton variant is a rare form of alpha-1-antitrypsin (AAT) deficiency, caused by a mutation in the SERPINA1 gene and associated with reduced AAT levels. Its clinical significance remains uncertain due to the limited number of reported cases. Methods: This study characterizes PI*Mmalton carriers within the EARCO (European Alpha-1 Antitrypsin Research Collaboration) registry an

Reversal of Roux-en-Y Gastric Bypass to Normal Anatomy-Experience of 70 Patients

BACKGROUND: A limited subset of patients undergoing Roux-en-Y gastric bypass (RYGB) may develop intractable symptoms that ultimately require reversal to normal anatomy. Existing literature on this subject is characterized by small cohort sizes, substantial variation in surgical techniques, and limited follow-up durations. However, this study presents the largest single-center series to date, compr

Time for a paradigm shift in shared decision-making in trauma and emergency surgery? : Results from an international survey

BACKGROUND: Shared decision-making (SDM) between clinicians and patients is one of the pillars of the modern patient-centric philosophy of care. This study aims to explore SDM in the discipline of trauma and emergency surgery, investigating its interpretation as well as the barriers and facilitators for its implementation among surgeons.METHODS: Grounding on the literature on the topics of the und

Attosecond temporal structure of non-consecutive harmonic combs revealed by multiple near-infrared photon transitions in two-color photoionisation

The metrology of attosecond pulse trains is based on a cross-correlation technique between a comb of extreme ultraviolet harmonics generated by the high-order harmonic generation process and a synchronised infrared field. The approach, usually referred to as reconstruction of attosecond beating by interference of two-photon transitions (RABBIT), allows one to recover the relative phase between the

Surgeons' perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts : results from an international survey

BACKGROUND: Artificial intelligence (AI) is gaining traction in medicine and surgery. AI-based applications can offer tools to examine high-volume data to inform predictive analytics that supports complex decision-making processes. Time-sensitive trauma and emergency contexts are often challenging. The study aims to investigate trauma and emergency surgeons' knowledge and perception of using AI-ba

Fallbeskrivning : yngling överlevde direktträffar av kniv i hjärta och lunga

In Sweden, penetrating injuries to the lung and especially to the heart are fortunately rare. We hereby present a case-report on a young man who was stabbed in the right lung and heart. The paramedics arrived at the scene one minute after the alarm and instituted mechanical ventilation and fluid infusion. Ten minutes later the young man arrived at the emergency department. By then the patient was

Arts on prescription intervention for primary healthcare patients with poor mental health or social isolation : a mixed-method study

Background: Primary healthcare providers are increasingly challenged in supporting patients with psychosocial needs. Arts on Prescription (AoP) has been shown to improve primary healthcare patients’ mental health wellbeing. The aim of the current study is to understand the psychosocial effect of participating in an Arts on Prescription programme. Methods: A total of 112 primary healthcare patients

Core-valence double ionization of carbon suboxide

We have measured the core-valence double ionization spectra of carbon suboxide above both the O 1s and C 1s edges. Following several core-valence cases known in the literature, to begin with the spectra are compared with the well-known single ionization valence photoelectron spectrum of this system, from which they surprisingly differ quite strongly. This motivates a comparison to electronic struc

A comprehensive review of Schisandra chinensis lignans : pharmacokinetics, pharmacological mechanisms, and future prospects in disease prevention and treatment

Lignans derived from Schisandra chinensis have attracted significant attention for their diverse pharmacological activities and clinical potential. This review presents a comprehensive analysis of the pharmacological properties of Schisandra chinensis lignans, including their antioxidant, anti-inflammatory, neuroprotective, hepatoprotective, antibacterial/viral, antidiabetic and anticancer effects

Self-supervised representation learning for geospatial objects : A survey

The proliferation of various data sources in urban and territorial environments has significantly facilitated the development of geospatial artificial intelligence (GeoAI) across a wide range of geospatial applications. However, geospatial data, which is inherently linked to geospatial objects, often exhibits data heterogeneity that necessitates specialized fusion and representation strategies whi

Perivascular macrophages in the central nervous system : insights into their roles in health and disease

Perivascular macrophages (PVMs) are a specialized subset of macrophages situated near blood vessels in the brain. Their strategic positioning around these vessels enables them to perform key functions in immune surveillance and response to inflammation and injury. These cells are crucial for modulating the immune response within the brain, contributing to normal central nervous system (CNS) proces

Communication aspects of feedback from workers’ health surveillance due to hand-arm vibration exposure − a scoping review

Background: The feedback of the surveillance results to the employee and the employer largely determines the impact of workers’ health surveillance on workers’ health and exposure. We are unaware of any guidebooks or articles on performing feedback on regulated workers’ health surveillance, e.g., for vibration-exposed workers. Objectives: To identify existing knowledge of the communication aspects

Case study on challenges in research with public partners : A personal data incident during recruitment for a survey study on ageing and housing

Objective: To highlight experiences from a personal data incident, which occurred during recruitment for a project focused on how housing choices and relocation are related to active and healthy ageing. Results: Based on established collaboration, the researchers and representatives of housing companies planned for recruitment. Invitations to participate was distributed to persons registered with

An echo state network for synthesizing the standard 12-lead ECG from a two-lead ECG obtained from a single touch of a wrist-worn device

Background: With the availability of a wrist-worn device capable of acquiring two ECG leads with a single touch, synthesis of the 12-lead ECG may be accomplished to facilitate clinical interpretation. Objective: This study proposes an echo state network (ESN) for synthesizing the 12-lead ECG from two leads simultaneously acquired using a wrist-worn device. Methods: The wrist-worn device, equipped

Weather warning archives reveal spatio-temporal hot spots of compound natural hazards

Individual natural hazards may be combined in different ways, leading to cascading or co-occurring effects, turning them into compound hazards. However, assessment of individual as well as compound hazards is often hampered by short or incomplete observational records of actual hazards, and records of various hazards that do not easily combine. In this study we propose an alternative way to detect

Association between a mobile team intervention in Swedish municipal home care and the effect on emergency department visits and hospitalizations among older adults

Background: Elderly individuals with chronic conditions or acute illnesses are major drivers of hospitalization, with frail patients frequently utilizing emergency department (ED) services. To ease this burden, many countries offer home-based medical services. In Region Halland, Sweden, a mobile team intervention in municipal home care (MHC) was introduced to support frail elderly patients. This s

Six propositions for care-centric planning and governance that promote sustainable cities

This Perspective suggests six conceptual propositions to advance care-centric planning and governance in support of SDG 11. By prioritizing relationships, responsiveness, and collective well-being, while also integrating empowerment, environmental stewardship, and cultural diversity, a care-centric approach fosters more inclusive and sustainable cities. Drawing on selected practice-based examples,

Testing the utility of GPT for title and abstract screening in environmental systematic evidence synthesis

In this paper we show that OpenAI’s Large Language Model (LLM) GPT perform remarkably well when used for title and abstract eligibility screening of scientific articles and within a (systematic) literature review workflow. We evaluated GPT on screening data from a systematic review study on electric vehicle charging infrastructure demand with almost 12,000 records using the same eligibility criter