Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a characteristic network, interact with blood cells, and initiate tissue repair. The fibrin network is porous and highly permeable, but the spatial arrangement of the external clot face is unknown. Here we show that fibrin transitioned to the blood-air interface through Langmuir film formation, producing a protective film

Nanostructures are found everywhere in our environment, of either natural oranthropogenic origin. Volcanoes emit them, breakdown of plastic releases them, andthey are even produced in candlelight. Designed nanostructures are used in sunscreen,food products, electronics and many more readily available products. Still, there are alot of things we do not know about their behavior. To call them miniscThis thesis presents the results of studies done on various biomolecules and their interactions with nanomaterials. The biomolecule sources are everything from purified, single proteins to the complicated mixture of blood serum and cell culture media. Similarly, the nanomaterial sources vary from spherical titanium dioxide, gold, and polystyrene nanoparticles to novel nanowires of gallium arsenide

EAN-kodens betydelse vid scanning av varorAtt arbeta som kassör vid utgångskassa anses vara ergonomiskt belastande. En vanlig uppfattning är att om kunden lägger varorna en och en på bandet samt vänder EAN-koden mot scannern, så minskar kassörens arbetsbelastning.Arbets- och miljömedicin Syd har i samarbete med Handelsanställdas Förbund genomfört en pilotstudie i kassaarbete vid scanning av varor.

The Paris Climate Agreement defined an ambition of limiting global warming to 1.5 °C above preindustrial levels. This has triggered research on stringent emission reduction targets and corresponding mitigation pathways across energy economy and societal systems. Driven by methodological considerations, supply side and carbon dioxide removal options feature prominently in the emerging pathway liter

The most frequent type of cerebellar infarcts involved the posterior inferior cerebellar artery (PICA) and superior cerebellar artery territories but bilateral involvement of lateral or medial branches of PICA is extremely rare. In this report, we present a 55-year-old male who admitted to hospital with vomiting, nausea and dizziness. On examination left-sided hemiparesia and ataxic gait were dete

In the cell, γ-tubulin establishes a cellular network of threads named the γ-string meshwork. However, the functions of this meshwork remain to be determined. We investigated the traits of the meshwork and show that γ-strings have the ability to connect the cytoplasm and the mitochondrial DNA together. We also show that γ-tubulin has a role in the maintenance of the mitochondrial network and functIn the cell, γ-tubulin establishes a cellular network of threads named the γ-string meshwork. However, the functions of this meshwork remain to be determined. We investigated the traits of the meshwork and show that γ-strings have the ability to connect the cytoplasm and the mitochondrial DNA together. We also show that γ-tubulin has a role in the maintenance of the mitochondrial network and funct

Blastocystis is a ubiquitous enteric protozoan found in the intestinal tracts of humans and a wide range of animals. Evidence accumulated over the last decade suggests association of Blastocystis with gastrointestinal disorders involving diarrhea, abdominal pain, constipation, nausea, and fatigue. Clinical and experimental studies have associated Blastocystis with intestinal inflammation, and it h

BackgroundHewes flap is a tarsoconjunctival eyelid flap, based at the lateral canthal tendon, and rotated and stretched to repair lateral defects in the lower eyelid commonly following tumor surgery. The aim of the present study was to monitor perfusion in a Hewes flap during reconstruction, which to the best of our knowledge, has not previously been done.MethodsA Hewes tarsoconjunctival eyelid fl

The tumor microenvironment consists of several interacting cell types. Cancer research focssed mainly on the malignant cell in the past. The importance of the tumor microenvironment is increasingly appreciated, as endothelial cells and immune cells were identified as targets for anti-tumor therapy. Targeted therapy against cancer-associated fibroblasts (CAFs) are not in clinical use for the treatm

Aims/hypothesis: Coronary artery disease (CAD) is a common complication among individuals with diabetes. A better understanding of the genetic background of CAD in this population has the potential to suggest novel molecular targets for screening, risk assessment and drug development. Methods: We performed a genome-wide association study of CAD in 15,666 unrelated individuals (3,968 CAD cases and