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KlimaSeniorinnen and the Question(s) of Causation

In my blog post, I turn to a more technical aspect of the judgment, namely the question of causation. I will untangle the analytical gymnastics that the Court performs regarding this question. I will argue that the reasoning regarding causation is confusing and that it is not clear how specifically the ‘real prospect’ test is applied for finding a breach.

Destination transitions and resilience following trigger events and transformative moments

Disasters and crises are increasingly seen as opportunities for transformation of the tourism system at various scales. From a resilience perspective, crises and disasters may act as trigger events for system change, sometimes described as the “disaster-reform hypothesis”. An integrative framework informed by different fields is used to analyse the destination development pathways following the Ka

In Situ Study of Growth Dynamics in Au-Seeded GaSb Nanowires

Understanding the growth dynamics of III-V nanowires is crucial to attaining the atomistic control of nanowire growth required for the fabrication of high-quality devices. In situ studies allow us to monitor the individual processes of the cyclic layer-by-layer growth, which permits us to gain more insight into the growth dynamics than using conventional growth studies. Here, we demonstrate how th

The myth of ‘Jacobin Kemalism’? : influence of the French Revolution on Kemalist elite and ideology during the early republican period

This study examines the first-hand sources of Kemalism to understand how and to what extent the French Revolution inspired the Kemalist elite and influenced Kemalism during the early republican period. In the literature, there is a general perception that the French Revolution and Jacobinism were highly influential on the Kemalists, but this perception mainly depends on broad interpretations witho

Similar parasite communities but dissimilar infection patterns in two closely related chickadee species

Hemosporidian parasite communities are broadly similar in Boulder County, Colorado, between two common songbirds-the Black-capped Chickadee (Poecile atricapillus) and Mountain Chickadee (Poecile gambeli). However, Mountain Chickadees appear more likely to be infected with Plasmodium and potentially experience higher infection burdens with Leucocytozoon in contrast to Black-capped Chickadees. We fo

Stability Analysis of Trajectories on Manifolds with Applications to Observer and Controller Design

This paper examines the local exponential stability (LES) of trajectories for nonlinear systems on Riemannian manifolds. We present necessary and sufficient conditions for LES of a trajectory on a Riemannian manifold by analyzing the complete lift of the system along the given trajectory. These conditions are coordinate-free which reveal fundamental relationships between exponential stability and

Kapacitetsbyggande för ekosocial integration : Utmaningar och möjligheter för Lunds kommun

Klimatförändringar och social rättvisa är två sammanlänkade utmaningar för städer och kommuner. I takt med att miljö- och klimatkriserna förvärras blir behovet av att sammanlänka ekologisk och social hållbarhet alltmer centralt för städers och kommuners omställning. Tidigare separata åtgärder för dessa områden har ofta misslyckats med att tillvarata synergier och hantera motsättningar. Projektet u

Inability to start or complete upper secondary school strongly predicts unemployment and psychosocial and psychiatric adversities – A register-based follow-up study from southwestern Sweden

Aim: To study academic, social and psychiatric outcomes among adults in the general population in southwestern Sweden. Groups of individuals born in 1998 and ineligible, eligible but not completed, and eligible and completed upper secondary school were followed in 2020. Methods: Data were retrieved from Statistics Sweden, the Swedish National Agency for Education, the Longitudinal Integrated Datab

Structure-functional characterization of Lactococcus AbiA phage defense system

Bacterial reverse transcriptases (RTs) are a large and diverse enzyme family. AbiA, AbiK and Abi-P2 are abortive infection system (Abi) RTs that mediate defense against bacteriophages. What sets Abi RTs apart from other RT enzymes is their ability to synthesize long DNA products of random sequences in a template- and primer-independent manner. Structures of AbiK and Abi-P2 representatives have rec

The Sulphur Threat To The 17th Century Warship Vasa

The royal warship Vasa sank on her maiden voyage in 1628. She was discovered in 1956 and in 1961, after 333 years at the bottom of the sea in the Stockholm harbour she was salvaged. Vasa, built mainly of oak, was one of the first major objects to be conserved with polyethylene glycol. She was sprayed continuously for 17 years followed by an 11 year long controlled drying procedure HBfors,[l]). In

Cystectomy for bladder cancer in Sweden - short-term outcomes after centralization

OBJECTIVE: Radical cystectomy (RC) for bladder cancer is associated with an inherent risk of complications and even postoperative mortality. The number of hospitals performing RC has decreased in Sweden over time, and since a formal regional centralization in 2017 cystectomy care is currently provided by nine hospitals. MATERIAL AND METHODS: In the Swedish National Urinary Bladder Cancer Register

Single-cell genomics of a bloom-forming phytoplankton species reveals population genetic structure across continents

The study of microbial diversity over time and space is fundamental to the understanding of their ecology and evolution. The underlying processes driving these patterns are not fully resolved but can be studied using population genetic approaches. Here we investigated the population genetic structure of Gonyostomum semen, a bloom-forming phytoplankton species, across two continents. The species ap

Gene fusions and microRNAs in cancer

The genome of cancer cells is unstable. Flaws in the DNA repair mechanisms of these cells can lead to the creation of gene fusions, where parts of two different genes are erroneously combined. Additionally, the expression of microRNAs (miRNAs), small regulatory molecules that control gene activity, is often dysregulated in cancer. In this thesis, we investigate miRNAs, gene fusions, and the interp

Swedish crisis preparedness planners' understanding and sense-making of preparedness work in a public organisation : Implications for future development

The sometimes rapid development of (new) threats and extraordinary events calls for a robust, flexible, and well-equipped civil crisis preparedness system to respond and limit the damage of crisis events. To achieve this, Swedish municipalities and regions are required by law to regularly perform and report risk and vulnerability analysis ‘bottom up’ to governmental agencies. When performed in lar

Noninvasive Pressure-Volume Loops Predict Major Adverse Cardiac Events in Heart Failure With Reduced Ejection Fraction

Background: Heart failure with reduced ejection fraction (HFrEF) is characterized by ventricular remodeling and impaired myocardial energetics. Left ventricular pressure-volume (PV) loop analysis can be performed noninvasively using cardiovascular magnetic resonance (CMR) imaging to assess cardiac thermodynamic efficiency. Objectives: The aim of the study was to investigate whether noninvasive PV

L-type Amino Acid Transporter 1 as a Therapeutic Target in Pancreatic Cancer

Metabolic rewiring is a key feature of cancer cells to support the demands of growth and proliferation. The metabolism of amino acids is altered in many cancers, including pancreatic cancer. The cellular uptake of amino acids is regulated by amino acid transporters, such as L-type amino acid transporter 1 (LAT1). Accumulating evidence suggests that LAT1 is overexpressed in pancreatic cancer and co