One of the most important challenges for modern society is how to feed the world in a sustainable manner. Agriculture is an essential part of food production, but at the same time it has many negative impacts on the environment, through for example pollution, nutrient leaching, and greenhouse gas emissions, and it is a big driver of biodiversity loss. Organic farming is a farming system that in ma

Cancer presently represents a significant global health challenge, illustrated by the high incidence and mortality rates associated with lung and breast cancer. Technological advances and concerted large-scale initiatives have yielded vast amounts of cancer data to be used for research purposes. The objective of this thesis is to capitalize on the current state of the bioinformatics field to devel

Radical right populist parties have often been treated as “pariahs,” being excluded from coalition politics in parliamentary democracies. We argue that negative rhetoric targeted at radical right populist parties in legislative debates is used by the established parties to distance themselves from such parties and that the incentives to do so depend on the political context. Using sentiment analys

Environmentally friendly InP/ZnSe core/shell quantum dots (QDs) with high absorption coefficients and tunable band gaps have demonstrated great potential for photoelectrochemical (PEC) water splitting. However, the tightly bound excitonic feature by inherent type I band alignment tends to reduce the charge separation efficiency, limiting their PEC performance. Herein, we devised heterovalent In3+

Sweden’s child welfare services are characterised by intra-organisational specialisation and collaboration with Barnahus as a standard procedure in cases of child abuse. This chapter examines what happens with social workers’ risk assessments when they are both filtered internally at different units and in relation to Barnahus and a criminal law-oriented logic. Various organisational tensions are

Treatment with the anti-angiogenic drug bevacizumab in addition to chemotherapy has shown efficacy for breast cancer in some clinical trials, but better biomarkers are needed to optimally select patients for treatment. Here, we present an omics approach where DNA methylation profiles are integrated with gene expression and results from proteomic data in breast cancer patients to predict response t

Background and Purpose: Differentiating idiopathic normal pressure hydrocephalus (iNPH) from neurodegenerative disorders such as progressive supranuclear palsy (PSP), Multiple System Atrophy—parkinsonian type (MSA-P), and vascular dementia (VaD) is challenging due to overlapping clinical and neuroimaging findings. This study assesses if quantitative brain stem and cerebellum metrics can aid in thi

Interleukin-1 (IL-1)-family cytokines are potent modulators of inflammation, coordinating a vast array of immunological responses across innate and adaptive immune systems. Dysregulated IL-1-family cytokine signaling, however, is involved in a multitude of adverse health effects, such as chronic inflammatory conditions, autoimmune diseases, and cancer. Within the IL-1 family of cytokines, six—IL-1

Defining minimal standards for data collection is key to creating interoperative, searchable genomic and clinical databases. We highlight here the 1+Million Genomes Minimal Dataset for Cancer, encompassing 140 items in 8 domains to foster the collection of cancer data, inform transnational cooperation and advance precision cancer medicine.

In November 2022 the European Commission launched a new regulatory framework proposal for packaging and packaging waste, EU Packaging and Packaging Waste Regulation, which includes mandatory reuse and refill targets of packed food products. With specific focus on perishable liquid food products, such as dairy, plant-based beverages, juices, and nectars, which are currently primarily available in s

This special issue explores the intertwining reconfigurations of labour and welfare in the Global South by bringing together eight empirical studies of different national and transnational contexts and three commentaries. It asks how Global South people and states alike have come to prioritize market logics as guiding principles for welfare systems, moving away from collective risk-pooling towards

One of the major open problems in complexity theory is proving super-logarithmiclower bounds on the depth of circuits (i.e., P⊈NC1). Karchmer et al. (Comput Complex 5(3/4):191–204, 1995) suggested to approach thisproblem by proving that depth complexity behaves “as expected”with respect to the composition of functions f◊g. They showedthat the validity of this conjecture would imply that P⊈NC1.Seve

Conventional dendritic cells (cDC) play key roles in immune induction, but what drives their heterogeneity and functional specialization is still ill-defined. Here we show that cDC-specific deletion of the transcriptional repressor Bcl6 in mice alters the phenotype and transcriptome of cDC1 and cDC2, while their lineage identity is preserved. Bcl6-deficient cDC1 are diminished in the periphery but

Business continuity management (BCM) is an analytic process capable of fostering the resilience of critical societal functions. While previous research on BCM primarily has focused on its applications within individual organizations, today's modern society involves networks of interdependent actors collectively delivering these essential functions to end users. This necessitates an expansion of BC

Cerium doped (Lu,Y)2SiO5 (or LYSO) single crystals have been studied by means of luminescence excitation spectroscopy in the temperature range from 7 up to 300 K. Vacuum ultraviolet excitations in 4.5–8 eV energy range from synchrotron radiation of 1.5 GeV storage ring of MAX IV synchrotron facility. It is shown that both type of Ce3+ emission centers (seven and six coordinated centers) are excite

Radio signals are used broadly as navigation aids, and current and future terrestrial wireless communication systems have properties that make their dual-use for this purpose attractive. Sub-6 GHz carrier frequencies enable widespread coverage for data communication and navigation, but typically offer smaller bandwidths and limited resolution for precise estimation of geometries, particularly in e

We construct a set of Wigner 6j symbols with gluon lines (adjoint representations) in closed form, expressed in terms of similar 6j symbols with quark lines (fundamental representations). Together with these Wigner 6j symbols with quark lines, this gives a set of 6j symbols sufficient for treating QCD color structure for any number of external particles, in or beyond perturbation theory. This faci

Multimorbidity, i.e., two or more non-communicable diseases (NCDs), is an escalating challenge for society. Venous thromboembolism (VTE) is a common cardiovascular disease and it is unknown which multimorbidity clusters associates with VTE. Our aim was to examine the association between different common disease clusters of multimorbidity and VTE. The study is an extended (1997–2015) cross-sectiona

The electronic structure of high-quality van der Waals multiferroic CuCrP2S6 crystals was investigated by applying photoelectron spectroscopy methods in combination with DFT analysis. Using X-ray photoelectron and near-edge X-ray absorption fine structure (NEXAFS) spectroscopy at the Cu L2,3 and Cr L2,3 absorption edges, we determine the charge states of ions in the studied compound. Analyzing the

Background Acute kidney injury (AKI) is a common and severe complication in patients treated at an Intensive Care Unit (ICU). The pathogenesis of AKI has been reported to involve hypoperfusion, diminished oxygenation, systemic inflammation, and damage by increased intracellular iron concentration. Hepcidin, a regulator of iron metabolism, has been shown to be associated with sepsis and septic shoc