Development and validation of an ultrahigh-performance liquid chromatography method for identity, assay and impurity testing of nicotine and preservatives in nicotine nasal spray
The topic of this study is to develop and validate an analysis method of nicotine nasal spray produced at McNeil AB. When developing the analysis method, several parameters were determined in advance to make the method more similar to other analysis methods at the company, making it more practical. However, other parameters were adjusted with the aim to improve the resolution and to fulfil the upd
