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Prevalence and treatment of diabetes mellitus and hypertension among older adults with intellectual disability in comparison with the general population

BACKGROUND: Diabetes mellitus and hypertension are risk factors for cardiovascular disease, which is the most common cause of death in the world. People with intellectual disability (ID) have been reported to have high rates of both these disorders. The aim of this study was to describe and compare prevalence ratios of diabetes mellitus and hypertension between older adults with ID and their age p

Heritability of End-Stage Renal Disease : A Swedish Adoption Study

Background/Aims: The heritability of end-stage renal disease (ESRD) among adoptees has not been examined so far. By studying adoptees and their biological and adoptive parents, it is possible to differentiate between the genetic causes and environmental causes of familial aggregation. This nationwide study aimed to disentangle the genetic and shared environmental contribution to the familial trans

The effect of the size of square microchannels on hydrodynamics and mass transfer during liquid-liquid slug flow

The present study investigated the influence of square microchannel (MC) size on hydrodynamics and mass transfer in the liquid-liquid slug flow regime. Three square MCs with the hydraulic diameters of 200, 400, and 600 μm were used. The employed method for estimating mass-transfer coefficients remarkably increased the accuracy of the results. The findings revealed that decreasing the MC size impro

Long term azathioprine maintenance therapy in ANCA-associated vasculitis : combined results of long-term follow-up data

Methods: Three hundred and eighty newly diagnosed ANCA-associated vasculitis patients from six European multicentre studies treated with AZA maintenance were included; 58% were male, median age at diagnosis 59.4 years (interquartile range: 48.3-68.2 years); granulomatosis with polyangiitis, n = 236; microscopic polyangiitis, n = 132; or renal limited vasculitis, n = 12. Patients were grouped accor

Magnetic deformation of the white dwarf surface structure

The influence of strong, large-scale magnetic fields on the structure and temperature distribution in white dwarf atmospheres is investigated. Magnetic fields may provide an additional component of pressure support, thus possibly inflating the atmosphere compared to the non-magnetic case. Since the magnetic forces are not isotropic, atmospheric properties may significantly deviate from spherical s

Two methods for normalisation of measured energy performance-Testing of a net-zero energy building in Sweden

An increasing demand for energy-efficient buildings has led to an increasing focus on predicted energy performance once a building is in use. Many studies have identified a performance gap between predicted energy use and actual measured energy use once buildings are in the user phase. However, none of the identified studies normalise measured energy use for both internal and external deviating bo

Transplantation of reprogrammed neurons for improved recovery after stroke

Somatic cells such as fibroblasts, reprogrammed to induced pluripotent stem cells, can be used to generate neural stem/progenitor cells or neuroblasts for transplantation. In this review, we summarize recent studies demonstrating that when grafted intracerebrally in animal models of stroke, reprogrammed neurons improve function, probably by several different mechanisms, e.g., trophic actions, modu

Outcome of peripheral T-cell lymphoma in first complete remission : a Danish-Swedish population-based study

In the present study, we investigate the outcome of 109 Danish and 123 Swedish patients with nodal PTCL in first complete remission (CR), and examine the impact of imaging-based follow-up (FU) strategies. The patients were selected by the following criteria: (a) newly diagnosed nodal PTCL from 2007 to 2012, (b) age ≥18 years, and (c) CR after CHOP or CHOEP therapy. FU guidelines in Sweden included

A nationwide structure for valid Long-Term oxygen therapy : 29-Year prospective data in Sweden

Background: Long-term oxygen therapy (LTOT) improves prognosis in COPD with severe hypoxemia. However, adherence to criteria for eligibility and quality of LTOT is often insufficient and varies between countries. The aim of this study was to evaluate a national structure for prescription and management of LTOT over three decades in Sweden. Methods: The study was a prospective, population-based stu

Balancing authority and autonomy in higher education by implementing an agile project management approach

This article develops and implements an agile management approach in higher education. Such an approach follows core practices, such as project plans. The project manager has to identify the agility drivers that represent changes and pressures; prioritize agility capabilities to take advantage of changes; identify agility providers to obtain agility capabilities; and make managerial choices to man

Defect-induced infrared electroluminescence from radial GaInP/AlGaInP quantum well nanowire array light- emitting diodes

Radial GaInP/AlGaInP nanowire array light-emitting diodes (LEDs) are promising candidates for novel high-efficiency solid state lighting due to their potentially large strain-free active emission volumes compared to planar LEDs. Moreover, by proper tuning of the diameter of the nanowires, the fraction of emitted light extracted can be significantly enhanced compared to that of planar LEDs. Reports

Political participation on Facebook during Brexit : Does user engagement on media pages stimulate engagement with campaigns?

This study investigates, over an 18-month period surrounding the 2016 Brexit referendum, the commenting activity of nearly 2 million Facebook users engaging with political news from British media or with the posts of referendum campaigns. We ask whether citizens’ engagement with political news on Facebook motivates their participation with political campaign posts, and we examine whether users com

Role and impact of the environment on entrepreneurial learning

This article is presenting an overview of the literature devoted to entrepreneurial learning and, more speci cally, those research bringing environmental elements into the study of the entrepreneurial learning process. Then, it shows how each of the four Special Issue selected research papers contribute to enhancing our knowledge of the complexity of the learning process vis-à-vis entrepreneurial This article is presenting an overview of the literature devoted to entrepreneurial learning and, more speci cally, those research bringing environmental elements into the study of the entrepreneurial learning process. Then, it shows how each of the four Special Issue selected research papers contribute to enhancing our knowledge of the complexity of the learning process vis-à-vis entrepreneurial

Mainstreaming climate adaptation : taking stock about “what works” from empirical research worldwide

Adaptation to a changing climate is unavoidable. Mainstreaming climate adaptation objectives into existing policies, as opposed to developing dedicated adaptation policy, is widely advocated for public action. However, knowledge on what makes mainstreaming effective is scarce and fragmented. Against this background, this paper takes stock of peer-reviewed empirical analyses of climate adaptation m

Carbon stocks and fluxes in the high latitudes : Using site-level data to evaluate Earth system models

It is important that climate models can accurately simulate the terrestrial carbon cycle in the Arctic due to the large and potentially labile carbon stocks found in permafrost-affected environments, which can lead to a positive climate feedback, along with the possibility of future carbon sinks from northward expansion of vegetation under climate warming. Here we evaluate the simulation of tundra

Microfluidics-based approaches to the isolation of African trypanosomes

African trypanosomes are responsible for significant levels of disease in both humans and animals. The protozoan parasites are free-living flagellates, usually transmitted by arthropod vectors, including the tsetse fly. In the mammalian host they live in the bloodstream and, in the case of human-infectious species, later invade the central nervous system. Diagnosis of the disease requires the posi

PUFA status and methylmercury exposure are not associated with leukocyte telomere length in mothers or their children in the seychelles child development study

Background: Leukocyte telomere length (TL) is associated with age-related diseases and early mortality, but there is a lack of data on the determinants of TL in early life. Evidence suggests that dietary intake ofmarine n-3 (v-3) polyunsaturated fatty acids (PUFAs) is protective of telomere attrition, yet the effect of methylmercury exposure, also found in fish, on TL is unknown. Objective: The ai