Microservice applications consist of a set of smaller services interacting in a graph structure to deliver the full application. Jobs will traverse this graph in different paths, both depending on the type of job, but also on the current load of different service replicas. Different paths will incur different scenario-specific costs, dependent on, e.g., deployment and the underlying cloud system.

Using hydraulic models in control design in district heating networks can increase pumping efficiency and reduce sensitivity to hydraulic bottlenecks. These models are usually white-box, as they are obtained based on full knowledge of the district heating network and its parameters. This type of model is time-consuming to obtain, and might differ from the actual behavior of the system. In this pap

Key points• Obsessive-compulsive disorder is a disabling mental disorder with a lifetime prevalence of around 2% with similar rates across age groups and countries.• Diagnosis is made based on a pattern of time-consuming, clinically distressing, or impairing obsessions and compulsions and most cases emerge during puberty or early adulthood.• Obsessions are recurrent, persistent, and intrusive thou

In this survey, we present the current status on robots performing manipulation tasks that require varying contact with the environment, such that the robot must either implicitly or explicitly control the contact force with the environment to complete the task. Robots can perform more and more manipulation tasks that are still done by humans, and there is a growing number of publications on the t

Lung transplantation is currently the only option for patients with end-stage respiratory diseases, but owing to various complications and adverse effects of the treatment in combination with the increasing demand for and limited access to donor organs, new strategies are needed. Recent advances in materials science, culture techniques, cell-phenotyping and isolation techniques, bioreactor enginee

Early and accurate diagnoses are important for successful cancer treatment. Lymph node involvement is often critical, and magnetomotive ultrasound (MMUS) has been proposed for its detection and characterization. MMUS relies on a magnetic contrast agent, for example, iron oxide nanoparticles, delivered to the tissue of interest, magnetically set in motion and detected using ultrasound. The magneto-

Side-channel resilience is a crucial feature when assessing whether a postquantum cryptographic proposal is sufficiently mature to be deployed. In this paper, we propose a generic and efficient adaptive approach to improve the sample complexity (i.e., the required number of traces) of plaintext-checking (PC) oracle-based sidechannel attacks (SCAs), a major class of key recovery chosen-ciphertext S

Background: The nature of free, uncomplexed prostate-specific antigen (s) in the circulation is still unknown. In this study, we developed novel anti-PSA antibodies using PSA produced by a metastasized cancer cell line, LNCaP, as an immunogen. Methods: Hybridoma cell lines were screened with different methods that aimed at finding antibodies specific for the forms of free PSA produced by LNCaP cel

Purpose: Prostate specific antigen (PSA) exists in the serum in several molecular forms that can be measured by immunodetectable assays: free PSA, PSA complexed to alpha 1-antichymotrypsin (complexed PSA) and total PSA, which represents the sum of the free and complexed forms. We determined the normal distribution of values and established the appropriate reference ranges for these 3 molecular for

Den psykiska ohälsan hos barn och unga i Sverige uppges öka över tid och är ett av vår tids största folkhälsoproblem. Men vad menas egentligen med psykisk ohälsa och hur har begreppet konstruerats inom den sociala barn- och ungdomsvårdens rättsliga normering? I den här rapporten visar författarna hur synen på psykisk ohälsa ges mening och förändras över tid i samspel med rådande samhällsnormer och

Lundquist and Seedorff [1] demonstrated the presence of a zymogen in human seminal fluid, that could be activated into an active enzyme by acidification to pH 2. As the enzyme was purified, it became evident that it was in fact equivalent to the minor gastric enzyme originally named as progastricsin (EC 3.4.23.3) [2–6].This report provides a short review on the similarities and differences between

Background: In ultra-rare sarcomas (URS) the conduction of prospective, randomized trials is challenging. Data from retrospective observational studies (ROS) may represent the best evidence available. ROS implicit limitations led to poor acceptance by the scientific community and regulatory authorities. In this context, an expert panel from the Connective Tissue Oncology Society (CTOS), agreed on

Differences by sex in lung cancer incidence and mortality have been reported which cannot be fully explained by sex differences in smoking behavior, implying existence of genetic and molecular basis for sex disparity in lung cancer development. However, the information about sex dimorphism in lung cancer risk is quite limited despite the great success in lung cancer association studies. By adoptin

In this study, a model „ADM606M Portable Multifunction Ratemeter /Scalar“ (Gamma GP110 Detector) was used to estimate the effective dose rate in (µSv.h-1). The data were analyzed for three specified hours per day (9:00 a.m., 11:00 a.m., and 1:00 p.m.) from January 2009 to June 2016. In July 2019, the gamma scout radiation meter (dosimeter) was used to measure the outdoor gamma effective dose rate

Introduction: Impaired functioning is seen in patients following replantation surgery to the thumb or fingers. Our aim was to explore long-term consequences and adaptation in daily life after a thumb and/or multiple finger amputation followed by replantation surgery during young age. Methods: Semi-structured interviews were conducted with nine recruited individuals and analysed using content analy