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Hemodynamic forces using four-dimensional flow MRI : An independent biomarker of cardiac function in heart failure with left ventricular dyssynchrony?

Patients with heart failure with left ventricular (LV) dyssynchrony often do not respond to cardiac resynchronization therapy (CRT), indicating that the pathophysiology is insufficiently understood. Intracardiac hemodynamic forces computed from four-dimensional (4-D) flow MRI have been proposed as a new measure of cardiac function. We therefore aimed to investigate how hemodynamic forces are alter

Coopted! : Mission-drift in a social entrepreneurial initiative engaged in a cross-sectoral partnership

Social entrepreneurship research highlights the collaborative nature of social entrepreneurial efforts. Further, acknowledging the embeddedness of social ventures in the wider socio-economic and cultural context, the literature stresses the need to move our analysis from the micro-level of intra-organisational practices to the meso-level of inter-organisational dynamics. To answer to these calls,

ABO-identical matching has no superiority in long-term survival in comparison to ABO-compatible matching in lung transplantation

Background: Even though identical blood group matching between recipient and donor is preferred, it is still not clear by how much this improves the outcome for patients who received a lung transplant (LTx), or whether there is any survival benefit. Earlier studies have yielded ambiguous results and few have investigated long-term survival. The aim of this study is, therefore, to explore the diffe

Micro-finance in a developed welfare state : A hybrid technology for the government of the outcast

Although microfinance is often thought of as a tool to address poverty in developing countries, it is also being introduced in a number of countries in the developed world. The paper presents a qualitative study of the first year of the introduction of microfinance to address vulnerable groups in Sweden. Savings banks and nonprofit organisations collaborated in the introduction of microfinance as

Orienting to polarized light at night - matching lunar skylight to performance in a nocturnal beetle

For polarized light to inform behaviour, the typical range of degrees of polarization observable in the animal's natural environment must be above the threshold for detection and interpretation. Here, we present the first investigation of the degree of linear polarization threshold for orientation behaviour in a nocturnal species, with specific reference to the range of degrees of polarization mea

Politicising Social Entrepreneurship : Three Social Entrepreneurial Rationalities toward Social Change

Scholars in the field of social entrepreneurship are challenging the researchers to produce empirical research on the social dimension of this phenomenon. Drawing on Foucault, this paper proposes the notion of ‘social entrepreneurial rationality’ to capture the social dimension of social entrepreneurship. The article builds on a comparative case study of three social ventures, each adopting a diff

The Psychic Life of Resistance : The Ethnic Subject in a High-Tech Region

The last 20 years have seen a flood of studies of resistance, ranging from collective to individual acts of resistance, from the study of material aspects to its more ideational ones. Yet students of resistance have neglected the psychological dimension of everyday individual acts of resistance to power. This article is a first step to remedy that oversight. Inspired by Butler’s reading of Foucaul

Prevention of Pancreatic β-Cell Failure in Type 2 Diabetes. By Targeting a Mitochondrial Voltage Gated Channel 1 and a Novel class of GPCRs.

It has been long known that hyperglycaemia-induced β-cell dysfunction precipitates type 2 diabetes (T2D) in insulin-resistant obesity, although the underlying mechanisms are still poorly defined. The few frequently used antidiabetic drugs on the market have still not satisfactorily demonstrated any long-lasting improvements of β-cell function and prevention of the disease. Islets synthesise and se

Non-uniform seasonal warming regulates vegetation greening and atmospheric CO2 amplification over northern lands

The enhanced vegetation growth by climate warming plays a pivotal role in amplifying the seasonal cycle of atmospheric CO2 at northern lands (>50° N) since 1960s. However, the correlation between vegetation growth, temperature and seasonal amplitude of atmospheric CO2 concentration have become elusive with the slowed increasing trend of vegetation growth and weakened temperature control on CO2 upt

Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients : an explorative analysis of a randomized trial

OBJECTIVE: Exposure to hyperoxemia and hypoxemia is common in out-of-hospital cardiac arrest (OHCA) patients following return of spontaneous circulation (ROSC), but its effects on neurological outcome are uncertain, and study results are inconsistent. METHODS: Exploratory post hoc substudy of the Target Temperature Management (TTM) trial, including 939 patients after OHCA with return of spontaneou

Characterization of the Combustion of Light Alcohols in CI Engines : Performance, Combustion Characteristics and Emissions

Alternative fuels for combustion engines are becoming increasingly popular as society is pushing to phase out fossil energy to reduce CO2 emissions. The compression ignition (CI) engine has a high overall efficiency which makes it a valuable option for the transport fleet, despite the well known NOx and soot pollutants it emits. These two pollutants are emitted due to a combination of high local cAlternative fuels for combustion engines are becoming increasingly popular as society is pushing to phase out fossil energy to reduce CO2 emissions. The compression ignition (CI) engine has a high overall efficiency which makes it a valuable option for the transport fleet, despite the well known NOx and soot pollutants it emits. These two pollutants are emitted due to a combination of high local c

Quantifying the effect of forest age in annual net forest carbon balance

Forests dominate carbon (C) exchanges between the terrestrial biosphere and the atmosphere on land. In the long term, the net carbon flux between forests and the atmosphere has been significantly impacted by changes in forest cover area and structure due to ecological disturbances and management activities. Current empirical approaches for estimating net ecosystem productivity (NEP) rarely conside

’Cultural diversity’ at work : ‘National culture’ as a discourse organizing an international project group

Research to date concurs in maintaining that performance of nationally homogeneous workgroups differs if compared to heterogeneous ones. Yet, results are mixed on the relationship between cultural diversity and workgroup outcomes. The article argues that cultural differences are given explanatory authority, cultural diversity acquiring a positivist status, and group members being treated as ‘dopes

Kista: The two sides of the Network Society

The term “network society” is often discussed as the society of the future, with technological saturation, knowledge-based work, and network structure being its defining characteristics. The network society implies a world populated by engineers, global telecom companies, highly mobile workers, cultural diversity, spin-offs, high-tech clusters, and venture capital. Theoretical approaches and empir