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The association between sleep duration, insulin sensitivity, and β-cell function : The EGIR-RISC study

Context: In the past decade, over 3 dozen studies reported a relationship between self-reported short sleep and disturbed glucose metabolism. A study with insulin sensitivity assessed according to the gold standard hyperinsulinemic-euglycemic clamp is, however, still missing. Objective: To evaluate the cross-sectional association of sleep duration with insulin sensitivity and β-cell function in th

Proposed ICDRG Classification of the Clinical Presentation of Contact Allergy

The International Contact Dermatitis Research Group proposes a classification for the clinical presentation of contact allergy. The classification is based primarily on the mode of clinical presentation. The categories are direct exposure/contact dermatitis, mimicking or exacerbation of preexisting eczema, multifactorial dermatitis including allergic contact dermatitis, by proxy, mimicking angioed

Vernacular architecture Reflections : Challenges and Future

Interest in vernacular structures has grown steadily over the past two decades. Vernacular structures around the world are the amalgamation of accumulated cultural, social and religious beliefs as well as practices. The valuable heritage embodied in the vernacular structures has served as sources of inspiration for centuries not only for architects, but also for a diverse, multi-disciplinary commu

Minus carbon and plus energy refugee shelter

This study discusses a proposal for a 37 m² refugeeearth shelter that could be built with the help of sevenpeople in 11 working days. The study is an experimental, participatory, living lab methodology for creating an eco-cycle shelter. The building’s skeleton is made from a minus carbon earth mix and is equipped with renewables that produce more energy than what the building consumes. No waste is

The circulatory system and a new cell type of the cephalocarid crustacean Hutchinsoniella macracantha

The circulatory system of Hutchinsoniella macracantha consists of a tubular heart in thoracic segments 1–6, a dorsoposterior channel, and body fluid (“haemocoelic”) sinuses. The heart, which is possibly closed anteriorly, has three paired ostia dorsolaterally in thoracic segments 2–4. The heart wall is formed by two cellular layers: an inner myocardium and an outer epicardium. The myofibrils are o

Baring it all- undressing Cambrian ´Orsten´phosphatocopine arthropods using synchrotron X-ray tomographic microscopy

Synchrotron radiation X-ray tomographic microscopy (SRXTM) was used to virtually dissect and peel the shields off of the microscopic, bivalved phosphatocopine crustaceans in the Cambrian ‘Orsten’ type of preservation of Sweden. Doing so opened up for an array of concealed internal structures to be observed in a fully enclosed specimen of Hesslandona ventrospinata and a semi-enclosed specimen of He

A novel ultrastructure on the corneocyte surface of mammalian nasolabial skin.

In many mammals, the skin of the rhinarium includes a thick epidermal layer. The skin surface can be smooth but can also display a structure formed of domes, ridges, and polygonal areas: a dermatoglyphic or rhinoglyphic pattern. Each structure consists of an easily visible, large area of the epidermis. The abdominal epidermis may or may not have a dermatoglyphic pattern. The abdominal skin examine

Using GIS as a decision making support tool for LEED credits

Green building rating systems are voluntary tools intended to promote sustainable building process through approaching several environmental issues that include sustainable design parameters related to the construction site and others related to its surrounding context. Decision making software support tools and methods are needed to guide practitioners on minimizing building’s environmental impac

Four sustainability goals in a Swedish low-growth/degrowth context

Continual environmental degradation and an unfair distribution of environmental burdens and benefits are two great challenges for humanity. Economic growth is often taken for granted when planning for the future. However, it is often argued that maintaining economic growth conflicts with keeping human activities adjusted to ecological boundaries and finite resources, at least for the more-develope

Neuropsychological findings in frontal lobe dementia

Neuropsychological investigations were performed on 18 patients with a clinical diagnosis of frontal lobe dementia supported by regional cerebral blood flow measurements. Nature and degree of cognitive impairment were examined with a comprehensive test battery. The results of the neuropsychological assessment could be described as three levels of cognitive impairment. The increasing levels of cogn

Neuropsychological tests as discriminators between dementia of Alzheimer type and frontotemporal dementia

The aim of this study was to examine whether cognitive test performance alone could distinguish patients with dementia of Alzheimer type (DAT) from those with frontotemporal dementia (FTD). Scores from three neuropsychological tests were used as discriminating variables in 28 cases with postmortem verified diagnoses. The selected tests measured verbal ability, visuospatial ability and verbal memor

Robust Time-of-Arrival Self Calibration with Missing Data and Outliers

The problem of estimating receiver-sender node positionsfrom measured receiver-sender distances is a key issue indifferent applications such as microphone array calibration, radioantenna array calibration, mapping and positioning using ultrawidebandand mapping and positioning using round-trip-timemeasurements between mobile phones and Wi-Fi-units. Thanks torecent research in this area we have an i

Smartphone Positioning in Multi-Floor Environments Without Calibration or Added Infrastructure

Indoor positioning for smartphone usershas received a lot of attention in recent years. Whilemany solutions have been developed, most rely on aneed for pre-deployment of infrastructure or collectingground truth data to train on. In this paper we see whatcan be done using existing WiFi-infrastructure andReceived Signal Strength from these to smartphones,not using any calibration of the signal envir

Performance on neuropsychological tests related to single photon emission computerised tomography findings in frontotemporal dementia

BACKGROUND: This study examines relations between regional cerebral blood flow (rCBF) and neuropsychological test results, age at onset and duration of disease in patients with frontotemporal-type dementia (FTD).METHOD: Sixteen patients with a diagnosis of probable FTD were examined using single photon emission computerised tomography (SPECT) with 99mTc-HMPAO as the tracer. The rCBF of 14 regions