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Evolution of the Serbian pharmaceutical market alongside socioeconomic transition

INTRODUCTION: South-eastern European socioeconomic transition followed by extensive health systems reforms has completely changed the pharmaceuticals market landscape in the region. Serbia, as the largest Western Balkans market, may serve as an example of such changes.METHODS: Descriptive trend analysis of national-level dispensing of medicines in Serbia 2004-2012 was performed.RESULTS: Total publ

Contemporary generic market in Japan - key conditions to successful evolution

The Japanese pharmaceutical market, the world's second largest, is traditionally renowned for the domination of patented drugs and the weakest generics share among major established economies. An in-depth observation of published evidence in Japanese/English language provided closer insight into current trends in Japanese domestic legislation and pharmaceutical market development. Recent governmen

Assessment of viral genotype impact to the cost-effectiveness and overall costs of care for PEG-interferon-2α + ribavirine treated chronic hepatitis C patients

BACKGROUND: Pegylated interferon alfa plus ribavirin protocol is currently considered the most efficient hepatitis C treatment. However, no evidence of costs comparison among common viral genotypes has been published.OBJECTIVES: We aimed to assess core drivers of hepatitis C medical care costs and compare cost effectiveness of this treatment among patients infected by hepatitis C virus with genoty

Cross-sectional survey on complementary and alternative medicine awareness among health care professionals and students using CHBQ questionnaire in a Balkan country

OBJECTIVE: To conduct a study on attitudes, knowledge, and use of complementary and alternative medicine (CAM) therapies in Serbia. Available data about CAM therapies in the region are scarce, opinions lacking from health sector. Balkan region countries had a delay in issuing national policies on CAM therapies.METHODS: The questionnaire used was based on previously validated CAM Health Belief Ques

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INTRODUCTION: The aim of our study was to develop and use a population pharmacokinetic model for assessment of individual valproate clearance in children and young adults suffering from epilepsy.MATERIAL AND METHODS: The analysis was performed using 52 steady-state concentrations of valproate collected from 26 epileptic patients during the routine clinical practice in our hospital. The mean values

Inverse correlation of valproic acid serum concentrations and quality of life in adolescents with epilepsy

BACKGROUND: Correlation between steady-state serum concentrations of antiepileptic drugs and both seizure control and adverse drug reactions frequency (two major determinants of quality of life in patients with epilepsy) is still matter of controversy.OBJECTIVE: The aim of our study was to investigate whether a correlation exists between steady-state serum concentration of valproic acid and qualit

Cost-effectiveness of ritodrine and fenoterol for treatment of preterm labor in a low-middle-income country : a case study

OBJECTIVES: In countries with high income, tocolytic therapy with beta-mimetic agents is a cost-effective strategy compared to placebo. In our study, the cost-effectiveness of two beta-mimetic agents, ritodrine and fenoterol, used in the management of preterm labor was compared in the setting of a low-middle-income transitional country, Serbia & Montenegro.METHODS: This case study was conducte

Inhibitory effects of selected antiepileptics on spontaneous motility of isolated human oviducts

OBJECTIVE: Spontaneous motility of the human oviduct is an important factor in the regulation of fertility that can be influenced by a variety of substances. In this study we examined the effects of several antiepileptic drugs on spontaneous contractions of isolated human oviducts.METHODS: The isolated ampullar and isthmic segments of Fallopian tubes, taken from 34 patients with extensive uterine

Solvent-induced toxic encephalopathy : Electrophysiological data in relation to neuropsychological findings

Male subjects with type 2A (n = 12) and 2B (n = 12) solvent-induced toxic encephalopathy and a reference group of healthy men (n = 12) without previous solvent exposure were studied using quantitative EEG and event- related potentials from an odd-ball and a dual-task paradigm. Subjects with toxic encephalopathy of types 2A and 2B showed markedly lower P300 amplitudes than did controls in both para

När spåren förskräcker. Visualiseringar av gränssättande händelser

Artikel om möten mellan historia och konst, framför allt med fokus på såväl nationella, triumfatoriska och monumentala historier som traumatiska historier som har tolkats konstnärligt med referenser till bland annat historiemåleri och monument. Texten är skriven i anslutning till utställningen Memory Matters på Skissernas museum i Lund.

TRUST IS GOOD, CONTROL IS BETTER, TRUST AND CONTROL IS BEST

Presentation at panel on Nordic Trust, International Anti-corruption Conference, Copenhagen. This paper argues that trust and control should not be seen as opposites, and that formulating a theory of Nordic corruption (which is based on networks and cronyism rather than bribery) a better approach is a hybrid concept of 'trusted control' or 'controlled trust'

European postgraduate curriculum in geriatric medicine developed using an international modified Delphi technique

Background: the European Union of Medical Specialists (UEMS-GMS) recommendations for training in Geriatric Medicine were published in 1993. The practice of Geriatric Medicine has developed considerably since then and it has therefore become necessary to update these recommendations.Methods: under the auspices of the UEMS-GMS, the European Geriatric Medicine Society (EuGMS) and the European Academy

Carbohydrates in food

Carbohydrates in Food, Third Edition provides thorough and authoritative coverage of the chemical analysis, structure, functional properties, analytical methods, and nutritional relevance of monosaccharides, disaccharides, and polysaccharides used in food. Carbohydrates have become a hot topic in the debate about what to eat. This new edition includes increased treatment of resistant starch, dieta